European Journal of Molecular & Clinical Medicine

Meningioma comprises majority of the intracranial tumors. They arise from the meningothelial cells (MECs) and are usually slow growing and benign in nature. Few meningiomas have a complicated histology and occur in compromising locations are very difficult to treat. Such cases have poor prognostic outcomes. This necessitates prompt diagnosis of the tumor and a proper understanding of its severity that can help in better management of the patients in future.

Background:Ovaries are one of the commonest sites of neoplastic lesions. Ovary is complex in its embryology, histology, steroidogenesis and potential for malignancy and presents wide variation in the clinical and morphological features The clinical stage of the neoplasm per se is inadequate to evaluate the optimum mode of therapy and to compare the therapeutic results. Histological classification of ovarian tumors forms an integral part of this evaluation Determination of various histopathologic patterns of ovarian tumors is very important in diagnosis as well as prognosis of ovarian tumors.Aims and Objectives: To classify and to study the histomorphology of various types of benign, borderline and malignant ovarian tumors and their relation to age and distribution of ovarian neoplasm.
Materials and Methods: During the period of three years from June 2019 to May 2022, 150 ovarian tumors were studied in the department of Pathology ACSR Govt Medical College, Nellore, AP, India.
Results: The overall incidence of ovarian tumors was 14.83% of total hysterectomy and oophorectomy specimens. The surface epithelial tumor formed the commonest tumor type accounting for 92 (66.67%) of ovarian tumors followed by germ cell tumors with 39 (28.26%) cases. The most frequent presentation of ovarian tumors was in the age group of 21-30 year in both benign and malignant tumours. Majority, 122 (88.4%) were benign and 16 (11.59%) were malignant. 94.93%of the tumors were unilateral, of which majority (85.51%) were benign. Majority of benign tumors 84.06%cases had cystic consistency,majority of malignant tumors 7.97%had mixed consistency.Other rare tumours Transitional cell carcinoma, undifferentiated carcinoma, immatureteratoma Haemangioma and lymphangioma were encountered.
Conclusion: A proper histological diagnosis and categorization of ovarian neoplasms in conjunction with clinical findings and recent diagnostic modalities assist in making accurate diagnosis which helps in the proper management.