Online ISSN: 2515-8260

Keywords : Bisphosphonates


Surgical outcome assessment in femoral fracture patients with or without teriparatide treatment

Dr. SAMUDRALA SREENIVAS, Dr. SAINATH REDDY MANDA, Dr. SAMUDRALA VIPANCHI

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 1445-1450

Introduction: Femoral fracture and atypical subtrochanteric fracture are thought to be uncommon side effects of long-term bisphosphonate treatment. Delay in bone healing may be caused by a decreased rate of bone turnover. Limited research has shown that teriparatide therapy may counteract the effects of bisphosphonates and promote bone repair.
Methods: A retrospective assessment of individuals with atypical subtrochanteric and femoral fractures associated with the use of bisphosphonates were examined. There were 18 female patients signed up. The characteristics of an unusual fracture were congruent with the radiographic findings. All underwent surgical intervention, and teriparatide usage was suggested after surgery. Perioperative results, clinical, and radiographic outcomes were all considered outcome indicators.

Retrospective evaluation of atypical periprosthetic femoral fractures and its associated risk factors

Dr. SAMUDRALA SREENIVAS, Dr. SAINATH REDDY MANDA, Dr. SAMUDRALA VIPANCHI

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 1451-1458

Aim: To evaluate atypical periprosthetic femoral fractures, its outcomes and its associated risk factors.
Methodology: This is a retrospective observational study carried out during duration of 2 years (April 2020 - March, 2022 at the Traumatology Department of college. All consecutive adult patients admitted with subtrochanteric or shaft fractures were evaluated with respect to the following inclusion and exclusion criteria. Inclusion criteria are based on the clinical and radiological features of AFF as defined by the American Society for Bone and Mineral Research major criteria. During the study period, 90 patients with subtrochanteric or femoral shaft fractures treated in the hospital that met the inclusion criteria. Of these, 10 patients had bilateral fractures on presentation. Surgeries were performed by trauma surgeons, and patients underwent standard rehabilitation following the procedure. Demographic information and surgical details were recorded from the hospital electronic records. The quality of reduction was evaluated by the postoperative standard X-rays in the anteroposterior (AP) and lateral views using digital pictures.