European Journal of Molecular & Clinical Medicine

Introduction: The aim of the study is to compare the outcomes of arthroplasty performed through medial parapatellar approach versus subvastus with oblique cut approach.
Materials and Methodology: After obtaining the permission from the institutional ethical committee, the study was carried out in those patients with osteoarthritis. This study was conducted as a prospective comparative study in assessing the factors influencing the total knee replacement surgeries through medial parapatellar and subvastus oblique approach. A total of 150 patients were included in the study and the proposed study period was about 12 months.
Results: A total of 150 patients were included in the study who are all underwent total knee replacement in our study centre and 109 patients were included in group – I that is MP approach (24 males and 85 females) group – II included 41 patients (7 males and 34 females) with the mean age observed at 71.6 ± 6.3 years and 73.3 ± 5.1 years. The pre-operative levels of haemoglobin level was observed to be potent significant risk factor as observed in this study which indicated that for every 1 unit rise in Hb, the probability of deferring the transfusion increases by 2.6 times. This result was in concordance with the results obtained from the earlier studies.
Conclusion: when comparing the subvastus approach with the medial parapatellar surgical approach in managing the total knee arthroplasty patients, early active straight leg raising for up to over 10 days after the surgical procedure had been reported.

Knee osteoarthritis is a common cause of severe pain and functional limitation. Total knee arthroplasty is an effective procedure to relieve pain, restore knee function, and improve quality of life for patients with end stage knee arthritis. The aim of this study was to investigate the inflammatory process in patients with primary knee osteoarthritis before surgery and in subsequent periods following total knee arthroplasty. A prospective study of 14 patients undergoing primary total knee replacements was conducted from October 2014 to May 2015 in our institution. The patients were evaluated by monitoring serum C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), knee skin temperature and clinical status. Measurements were carried out preoperatively and postoperatively on day 2 and 2nd week, 6th week, 14th week and 24th week during follow-up review. The CRP was elevated on the 2nd postoperative day but fell to preoperative values at two weeks postoperatively. CRP returned to within the normal range by six weeks postoperatively. In addition, the postoperative ESR showed a slow rise with a maximum level at two weeks after surgery and returned to within normal range at 14 weeks postoperatively. The difference in skin temperature between operated and contralateral knee had a mean value of 3.9C at two weeks. The mean value decreased to 3.4C at six weeks, 2.3C at 14 weeks, and 1.0C at 24 weeks. The difference in skin temperature decreased gradually and eventually there was no statistically significant difference at 24 weeks after surgery. A sustained elevation in serum CRP, ESR, and skin temperature must raise the concern of early complication and may suggest the development of postoperative complication such as haematoma and or infection.

Knee osteoarthritis is one of the most common joint disorders, and it causes severe pain and immobility. Total knee replacement (TKA) is very effectively relieves pain and improves knee function in patients with late-stage knee osteoarthritis. However, TKA is expensive and complex, and some patients need a second revision. The study included patients with medial compartment osteoarthritis, who were treated by proximal fibular osteotomy. The patients were diagnosed of knee osteoarthritis by American College of Rheumatology criteria and severity of disease was graded by Kellgren and Lawrence grading system. In our study, total number of patients was 27. Among them 3 were bilateral cases. Hence total number of knees was 30. Among 30 knees, 14 were right knees and 16 were left knees. The diagnosis of stage of osteoarthritis was done by using Kellgren and Lawrence classification system. Among 30 knees, 16 cases were in Stage 2, 13 cases were in Stage 3 and 1 case was in Stage 4