Online ISSN: 2515-8260

Keywords : Fine needle aspiration cytology (FNAC)


Dr K Lalitha Sree MD Dr Jyoti Brahmaiah MD Dr K Dileep DNB

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 2542-2549

To calculate the incidence of different types of thyroid lesions in rural people.In the diagnosis and characterisation of various thyroid lesions, ultrasonography is frequently utilised as the first investigative modality.
Objective :To assess the diagnostic accuracy of ultrasonography in distinguishing benign and malignant thyroid nodules by correlating sonographic findings with pathological diagnosis as a reference..
Method: From June 2020 to  December 2021, a prospective study was conducted on 100 patients who visited the  Apollo medical college and District head quarters hospital,              in the OPD of the department of radio diagnostics. All patients with thyroid swelling, mass, or enlargement were examined with  USG before undergoing FNAC.
Results: Of the 120 Thyroid disease patients in my study, 77 percent were females and 23 percent were males. The patients with the highest number of instances were between the ages of 41 and 50, accounting for 37 percent of all cases. 'Lump in the neck' was the most common complaint. Euthyroidism was the most common diagnosis (73). Solitary Thyroid Nodule was the most prevalent disease found on thyroid sonography (42percent ). The diagnostic accuracy of high resolution sonography in thyroid disorders was 84 percent Sensitivity and 96 percent Specificity.
Conclusion: Many malignant or potentially malignant thyroid nodules can be detected with ultrasonography. Although there is some overlap in the appearance of benign and malignant nodules on ultrasonography, some ultrasonography features can aid distinguish between the two. Even though it can report malignancy of the follicular variety, FNAC can diagnose benign disorders and can also be used as a supplement to ultrasonography features to signal malignancy.


Dr G Prathima, Dr N. Sailarekha

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 2825-2838

The most common target organs where fine needle aspiration cytology (FNAC) is performed are salivary glands because of their superficial location and easy accessibility introduced into a mass, cellular material is aspirated, and a cytological diagnosis is rendered as It separates reactive and inflammatory processes that do not require surgical intervention from neoplasia and benign from malignant tumors.
To study the cytomorphological features in lesions of salivary glands. To correlate the cytological features with histopathological features wherever possible. To evaluate the diagnostic utility of fine needle aspiration cytology of lesions in the salivary glands.
A total of 120 patients with salivary gland diseases were included in the study. This is a retrospective cohort study, undertaken in the Department of Pathology, Fathima Institute of Medical sciences, Kadapa during the period of Jan 2016 to Feb 2020. The sensitivity, specificity and overall diagnostic accuracy was calculated using Galen and Gambino method.
Our study included 120 patients with salivary gland diseases. Age group of patients with salivary gland diseases ranged from 10 years to 88 years with the mean age of 44.62 years. Majority of the patients belonged to the age group of 31-40 years (35%). Male to Female ratio was 1.25: 1. Among the 120 patients, most common non neoplastic 67.52%, benign 71.79% and malignant 28.20% lesions.
FNAC of salivary gland is a reliable and sensitive diagnostic method for diagnosis of salivary gland lesions. It not only provides preoperative diagnosis for management but also can prevent unnecessary surgeries.