European Journal of Molecular & Clinical Medicine

Acute appendicitis is a commonly encountered surgical emergency it has a lifetime prevalence of 1 in 7. With an incidence of 1.5-1.9 per 1000 in male and female population, and 1.4 times more common in men. The diagnosis is based on a thorough clinical history and examination. It is well supported with efficient laboratory investigations like elevated leucocyte count and ultrasound of the abdomen. Acute appendicitis is a common problem yet a difficult diagnosis at times specially in young and elderly females. Females of reproductive group are more prone for other genitourinary problems that may mimic acute appendicitis. Any delay in performing an appendicectomy to improve its diagnostic accuracy, can increase the risk of complications like appendicular lump, perforation and sepsis, which will in turn increase the morbidity and mortality

Background: As an alternative to surgical removal of the appendix, antibiotic medication has been suggested for the management of appendicitis. Those participants in the study who had an appendicolith were at a greater risk for complications and appendectomy than those participants who did not have an appendicolith

Background: Given the foregoing, the aims of the present study were to (1) establish whether hyperbilirubinemia is associated with acute appendicitis; (2) evaluate its validity as a diagnostic marker for acute appendicitis; and (3) establish whether elevated bilirubin levels might predict appendicular perforation. The goal of this study is to determine whether or not preoperative serum bilirubin levels are useful for diagnosing appendicular perforation. The goals of this study were to (1) determine whether serum bilirubin is associated with acute appendicitis, and (2) evaluate its usefulness as a diagnostic marker for this illness. For the purpose of determining whether or not elevated serum bilirubin levels can be used as a predictor of appendicular perforation.
Results: Eighty individuals who were diagnosed with acute appendicitis or appendicular perforation and needed immediate appendectomy were included in our analysis. Subjects were given proper resuscitation prior to participation in the study. In order to collect and record patient data, we employed the standard proforma. Patients with complex appendicitis often require a longer recovery time (9.5 days) than those with acute appendicitis (5.5 days). The postoperative diagnosis is statistically significantly related to the length of hospital stay (p0.0001). This highlights the need for a novel diagnostic aid for acute appendicitis. Hyperbilirubinemia has been linked to acute appendicitis, and its significance to the condition has been hypothesised in the medical literature. The hope that serum bilirubin would be useful as a new laboratory marker in the diagnosis of acute appendicitis prompted the current investigation. The purpose of this research was to investigate the association between hyperbilirubinemia and acute appendicitis, to test its validity as a diagnostic marker for this condition, and to determine whether or not elevated bilirubin levels are a reliable predictor of appendicular perforation.
Conclusion: Eighty patients hospitalised with a preoperative diagnosis of acute appendicitis who underwent emergency appendectomy between November 2019 and October 2021 will be included in a two-year prospective study conducted by the Department of General Surgery at NRI Medical College, Chinakakani. The total blood bilirubin levels of individuals with perforated and gangrenous appendicitis were substantially greater than those of those with acute appendicitis. When predicting gangrenous or perforated appendicitis, a high total serum bilirubin level has a high negative predictive value but low specificity. Total blood bilirubin is therefore a valuable indicator in patients suspected of perforated or gangrenous appendicitis, and should be used in conjunction with the clinical examination and other laboratory techniques to evaluate patients suspected of appendicitis.

Aim: To study the efficacy of laparoscopic appendectomy as well as conversion rate of laparoscopic appendectomy to open appendectomy.