Online ISSN: 2515-8260

Keywords : Nanocomposite

Smart Biosensor for Monitoring Human Health- A Review

Dr. Kamala Mitra

European Journal of Molecular & Clinical Medicine, 2023, Volume 10, Issue 1, Pages 3414-3421

The importance of biosensor research is expanding, as it benefits from cutting-edge knowledge that enables innovative biosensing approaches. Biosensors are classified according to their biorecognition pathway, with the biocatalyst group consisting of enzymes, the bio-specific subset consisting of nucleic acids and antibodies as well as the microbiomes consisting of microbial species. The uniqueness, responsivity, and fast reaction of various electrochemical devices, combined with the specificity of bioreceptor molecules,gave advantage to electrochemical biosensors. The use of electrochemical sensors in diagnostic purposes also provide a precise and efficient response for biomarker assessment, with glucose sensors for diabetics being the most effective. This paper provides a review of biophotosensors for sample matrix  such as lactate, glucose, Acetyl Choline Esterase (AChE), or protein kinase, collagenase, and others


Sneha Sinha; Dr.Kimaya Kakde; Dr.Akshata Sharma; Dr. Pavan Bajaj

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 1795-1801

The concept of nanocoatings was given by Chai et al., 1995 so as to enhance the mechanical as well as biological properties of Hap (hydroxapetite). This material does not have ideal mechanical properties and due to its bulk porosity, HAp can’t be used to take up load, and is therefore used for coating for utilizing its ductility of the substrate level. One can increase the mechanical properties of HAp by forming HAp nanocoatings. It can be achieved when HAp is united with other nanoscale based materials as secondary phase. Thin films of polymer(biodegradable) with gentamicin have been mixed to function as ‘composite coatings’ for metallic implants as well as devices which fix fractures to keep away from infections associated with implants. Calcium phosphate can imitate structure as well as composition of bone mineral called normal hydroxyapatite (HAp). Thus, it becomes a perfect alternative when thinking of an appropriate biomaterial in order to replace and imitate bone such as in case of an implant. Calcium phosphate has a special consideration on its introduction in the dental fields as it is chemically similar to bone of a human being, especially in terms of its characteristics of dissolution which enables the growth as well as regeneration in bones. Calcium phosphate nanocomposite coatings are merged with other materials which are micro or nanosized which increases its mechanical properties. Development of a newer generation of nanocomposite coating is recently being known which have nanomaterials like bioglass, carbon nanotubes as well as collagen to enhance ‘osseointegration’. The initiative of nanocoatings and nanocomposites is to develop the biological and mechanical properties of calcium phosphate and alter properties related to surface of implants which are used in dentistry to speed up the process of healing and thus nanocoatings are being introduced in dentistry