Keywords : Cold Pressor Test
Sympathetic Activity and Heart Rate Variability in Response to Cold Pressor Test and Hand Grip Test among Obese and Non-obese Adults: An Original Research Study
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 7, Pages 952-958
Background: Obesity is a health hazard throughout the world. weight gain and obesity are responsible for a growing threat to health throughout the world objectives: To evaluate and compare the cardiovascular autonomic response to cold pressor test and hand grip test among obese and non-obese adults.Methodology: Cardiovascular sympathetic function tests were carried out in 100 obese adults and 100 non obese adults aged between 28-58 years. Recording of ECG was performed in normal breathing, deep breathing and in condition of cold pressor.Time-domain method was used to record HRV Results: Study demonstrated significant decreased BP(BP)(systolic and diastolic) to cold pressor and to sustained handgrip. Responses in cases were significantly correlated to Body Mass Index. Our findings shows increased sympathetic activity was seen in obese patients and vagal activity was also withdrawn. Conclusion: There is remarkable change observed in the cardiac autonomic dysfunction responses between obese and non-obese subjects. Normal BMI showed a better HRV response to cold pressor test, indicating a better parasympathetic activity as compared to obese subjects. In cold pressor test BP was reduced in obese compared to non-obese individuals suggesting decreased vascular sensitivity to the amplified adrenergic activity in healthy obese individuals(adults).