Keywords : transdermal administration
Efficacy of fentanyl transdermal patch in impacted mandibular third molar surgery- A original research
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 7, Pages 8724-8729
Aim: The purpose of the present study was to assess the efficacy of fentanyl transdermal patch in case of impacted mandibular third molar surgery.
Methodology: 20 patients within the age group of 18–40 years with asymptomatic impacted mandibular third molars were equally divided into 2 groups as group A & group B which underwent surgery in Local Anaesthesia. In every patient one side belonged to group A and other side belonged to group B. 50 μg FTS was applied in group A while placebo patch was applied in group B.
Results: Patients in group A performed significantly better than group B in terms of mean pain intensity scores assessed by VAS and VRS along with minimum need of post-operative rescue analgesics.
Conclusion: It was found that FTS resulted in significantly better pain relief, longer pain-free intervals, and lesser post-operative analgesic consumption.