Online ISSN: 2515-8260

Keywords : Pregnancy


Prevalence of Urinary Tract Infection and Its Associated Risk Factors In Pregnant Women

DR UMESH SURESH SABALE, DR PRASHANT SURYARAO, Ms. RUTUJA SAMPAT WALKE

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 989-996

Urinary tract infections (UTI) are the most common bacterial infections during pregnancy.
Untreated UTI can be associated with serious obstetric complications. This cross-sectional
study was carried out to determine the prevalence of UTI among pregnant women. UTI was
diagnosed using mid stream urine (MSU) culture. Using >10’5 colony forming unit per millilitre
as a significant level of bacteriuria, the prevalence was found to be. There was a high
incidence of infection in 21-25 years age group (43.75%). There was also a high incidence of
infection in the third trimester of pregnancy (51.56%) compared to first (17.18%) and second
trimester (31.25%). Multiparty is associated with increased urinary tract infections in pregnancy.
Regarding education 10% were literate and 90 % were illiterate. Prevalence of bacteriuria
was 94% in women who had past history of urinary tract infection.80% were sexually
active. E.coli was the most frequently isolated pathogen. These findings underscores the importance
of screening all pregnant women for significant bacteriuria, so that positive cases
should be treated subsequently with antibiotics in order to reduce the adverse effects on both
maternal and fetal health.

Manual vacuum aspiration with medical method of abortion in termination of pregnancy up to 9 weeks of gestational age: A comparative study

Soubhagya Talawar,Rashmi Naganagoudar,Hanumant V Nipanal

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 1109-1118

Introduction:Unsafe abortions are a serious public health issue in India, involving the expulsion or extraction of the product of conception and causing controversy.Unmet demand exists for a simple, effective early pregnancy termination method that is both accessible and safe. Medical abortion using mifeprostone and misoprostol and surgical abortion using manual vacuum aspiration are two procedures that meet this need.
Materials and Methods:All requirements outlined in the MTP Act of 1972 by the Government of India were followed in this study. On the first day of the medical abortion, the patient was given 200 mg of mifepristone orally. After 48 hours at home, the patient was told to keep using Tab. Misoprostol 800ug vaginally.A 60ml double-valved manual vacuum aspiration syringe was used for MVA. Following the MVA syringe's attachment, the contents were aspirated. Villi on fresh tissue served as proof that the procedure was successful.The aspirated uterine contents were placed on a piece of gauze and examined to determine the gestational sac. Each woman was under observation for at least four hours following the procedure. The vital signs were examined before discharge. Inj. Women with Rh negative blood groups received 300ug of anti-D within 72 hours of the abortion.

EVALUATION OF OUTCOME IN PREGNANCY COMPLICATED BY FIBROID UTERUS: AN OBSERVATIONAL STUDY

Piyush Vohra, Geetika Gupta Syal, Rita Mittal, Binakshi Nevatia, Shivika Mittal

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 1831-1835

Background: The present study was conducted with the aim of assessing the outcome of pregnancy complicated by fibroid uterus.
Materials & methods: 50 subjects with presence of fibroid uterus were enrolled. Complete demographic details of all the patients were obtained. Assessment of the increase in the size of the fibroid and degeneration and other obstetric complications was done. All the results were recorded in Microsoft excel sheet and were analysed by SPSS software. 
Results: Pain abdomen was found to be present in 18 percent of the patients, while spontaneous miscarriage occurred in 6 percent of the patients. Postpartum occurred in 8 percent of the patients while threatened preterm labor occurred in 6 percent of the patients.
Conclusion: Fibroid uterus increases the risk of associated complications.

Prevalence of asthma and respiratory symptoms during pregnancy: An observational study

Dr. ILA Agarwal, Dr. Shalini Nagpal, Dr. Abdul Wahab Mirza

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 2105-2108

Background: Asthma attack is the most common respiratory symptom observed and is of great concern. Throughout the world asthma cases are increasing during pregnancy. The major issue is that the control levels of asthma is changing during pregnancy so the management is a little difficult during pregnancy.
Objective: The present study was undertaken to observe the prevalence of asthma and respiratory symptoms during pregnancy.
Materials and methods: 40 pregnant women attending OPD in the hospital were part of the study after obtaining the written informed consent. Confidentiality of the data was maintained. Willing pregnant women were included in the study. Pregnant women with any other complications severe were excluded from the study. Respiratory symptoms were examined during the general physical examination by an expert physician.
Results: The age group of the participants ranges from 22-30 years. 25% of individuals have asthma. 37.5% of individuals have wheeze without cold, 15% of individuals have nasal allergies. 27.5% have shortness of breath. 5% of individuals have a history of smoking. 15% of individuals are currently under the medication for asthma.
Conclusion: The present study results explained that wheezing without cold and shortness of breath are the most common respiratory symptoms during pregnancy. Further detailed studies with a higher sample size are recommended to understand better the respiratory symptoms during pregnancy.

A Study on Maternal and Fetal Outcome in Women with Severe Anaemiain Labour

Viplava, Siddula Shireesha, Leela Regalla

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 825-834

Background: In pregnancy, anaemia has a significant impact on the health of fetus as
well as that of mother. It is one of the leading causes responsible for maternal and
perinatal morbidity and mortality. The objectives of the study are to find out the effect
of severe anaemia on women in labour affecting maternal and fetal outcome.
Materials and Methods: This a prospective case control study undertaken in the
Department of Obstetrics and Gynaecology, Govt Maternity Hospital, Petlaburz
attached to Osmania Medical College, Hyderabad. The period of study was from 1st
December 2019 to 31st December 2021.There were a total of 160 study subjects, 80 cases
of severe anaemia (Hb<7gm %) and 80 non anaemic controls (Hb≥ 11gm %).
Results: Low socio economic status (86.25%), inadequate antenatal care (38.75%),
multiparity (71.25%) and no iron supplementation (52.5%) were associated with severe
anaemia cases. Microcytic hypochromic anaemia was more prevalent (76.25%),
suggesting nutritional inadequacies as a cause of anaemia. It was seen that the incidence
of preterm labour (22.5%), atonic PPH (2.5%), sub involution of the uterus (2.5%),
CCF (1.25%), abruptio placentae (1.25%) and maternal mortality (1.25%) was more in
cases of severe anaemia than in the control group. Adverse fetal outcome in the form of
preterm birth (22.5%), low birth weight babies (41.25%), IUGR (13.75%), birth
asphyxia (11.25%), and perinatal mortality (11.25%) was more in the anaemic group
than the controls.

Acute kidney injury in obstetrics: Varied pathologies and outcomes.

Somashekhar HK, Chandrashekhar Shrivastava, Pragyan Paramita Pradhan, Pavan Bhargava Chandramohan

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 1984-1987

Background: Acute Kidney Injury (AKI) is the sudden loss of renal function. Multiple causes of AKI exist that include those that afflict the general population, and those that are associated with pregnancy. AKI in pregnancy is of particular challenge as there are physiological alterations of renal function in pregnancy. The diagnosis is by abnormalities of renal function tests in addition to the abnormalities reflecting underlying pathologies. Management depends on underlying causes and the prognosis can often be positive.
Material and methods: We present three cases of AKI in pregnancy, their evaluation and management.
Results: The first patient had AKI due to septic abortion and was treated by dialysis. The second patient had AKI due to preeclampsia with severe features and was treated by termination of pregnancy and multiple anti-hypertensives. The third patient had AKI due to hyperemesis gravidarum and was treated aggressively with fluids and anti-emetics.
Conclusion: Early recognition and initiation of appropriate therapy can lead to favourable outcomes in AKI.

Risk factors of intrauterine growth restriction in term pregnancy

Dr. Sahana PR, Dr. Jeevitha H, Dr. Prajwal M, Dr. Chandrashekar K

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 1620-1624

Fetal growth restriction (FGR) is a pathological condition in which a fetus has not achieved his genetic growth potential, regardless of fetal size (1) Worldwide FGR is observed in about 24% of newborns; approximately 30million infants suffer from FGR every year. The burden of FGR is concentrated mainly in Asia which accounts for nearly 75% of all affected infants. National neonatal perinatal database of India reported the incidence of FGR to be 9.65% among hospital born live birth infants. Study was conducted for all cases with clinical/ Sonological term FGR admitted under department of OBG. A detailed history as per questioner will be taken with general physical examination and investigations will be done as per requirement. The accumulated data was evaluated and statistically analyzed. In the present study 70 patients with term gestation with FGR were recruited. Maternal (74.28%) was the commonest cause followed by Idiopathic (11.43) and Placental (10%) and Fetal (4.29%) causes. Among Maternal causes Pre Eclampsia was found to be in 50% cases. Most of the patients (50.7%) required caesarean section. A total of 9 (12.86%) neonate had birth weight of <1.5 kg, 48.6% had Birth weight between 1.6 to 1.9kg, 38.5% had birth weight between 2-2.4kg and 95.8% had asymmetrical FGR, 4.2% were symmetrical. 26 (40%) neonates had morbidity with 17(24.3%) neonatal mortality with Respiratory distress syndrome (41.18%) being most common cause. No Maternal Mortality.

Assessment of thyroid functions in early pregnancy

Dr Ramakant Rawat, Dr Vijay Kumar Verma, Dr Rajani Rawat, Dr. Amit Varshney, Dr Anima Dayal

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 2090-2095

Background: Measurement of serum free T4 concentrations and TSH is helpful in
assessing thyroid function. During the first trimester of pregnancy, free T4 levels
measured by analog immunoassays may be unreliable, as measurements using 2
different assays were not reproducible. The present study was conducted to assess
thyroid functions in early pregnancy.
Materials & Methods:
Results: Age group 18- 21 years had 28, 22-25 years had 25, 26- 29 years had 20 and 30-
33 years had 7 patients. Subclinical hypothyroidism was seen in 20, euthyroidism in 4,
overt hypothyroidismin 8, subclinical hyperthyroidism in 45 and overt hyperthyroidism
in 3. The mean TSH (mIU/l) in subclinical hypothyroidism was 4.31, in euthyroidism
was 1.48, in overt hypothyroidism was 10.32, in subclinical hyperthyroidism was 0.016
and in overt hyperthyroidism was 0.06. The mean FT3(pg/ml) level in subclinical
hypothyroidism, euthyroidism, overt hypothyroidism, subclinical hyperthyroidism and
overt hyperthyroidism was 4.08, 3.94, 1.54, 4.2 and 7.52 respectively. The mean
S.FT4(ng/dl) level in subclinical hypothyroidism, euthyroidism, overt hypothyroidism,
subclinical hyperthyroidism and overt hyperthyroidism was 1.20, 1.28, 0.48, 1.6 and 4.2
respectively.
Conclusion: The high prevalence of thyroid disorders in pregnant women makes it
necessary to screen all the pregnant women in early pregnancy.

A Study of Maternal and Foetal Outcomes in Cases of Asymptomatic Bacteriuria

Dandi Amitha Kumari, Jalli Padmaja, Kranthi Talari

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 9981-9989

Background:To determine the number of women with asymptomatic bacteriuria
(Group A) and the number of women with symptomatic bacteriuria (Group B) (Group
B). To identify the most common pathogenic organism in women with asymptomatic
bacteriuria. To compare the outcomes of pregnancies in groups A and B (maternal and
foetal morbidity).
Materials and Methods: Pregnant women visiting the antenatal clinic of the Department
of Obstetrics and Gynecology in Govt Medical College/General Hospital Suryapet for
the first time in 20 weeks to 36 weeks were the subjects of this prospective study.
Results: The study included 250 pregnant women starting at 20 weeks of gestation.
Urine culture and sensitivity testing were performed to check for asymptomatic
bacteriuria. Asymptomatic bacteriuria was found in 8.8 percent of the study population.
E.Coli was the most common pathogen, accounting for 63.63 percent of all cases.
Asymptomatic bacteriuria was associated with increased maternal morbidity (18.18
percent ). Those who did not have asymptomatic bacteriuria had lower morbidity (9.1
percent ). Fetal morbidity was higher (21.4 percent) in kids whose mothers had
asymptomatic bacteriuria than in those whose mothers did not have silent bacteriuria
(9.3 percent ). Preterm labour was the most prevalent maternal morbidity (18.18
percent), while low birth weight was the most common foetal morbidity (18.18 percent ).
There was no maternal or foetal death.

Acute kidney injury in obstetrics: Varied pathologies and outcomes

Somashekhar HK, Chandrashekhar Shrivastava, Pragyan Paramita Pradhan, Pavan Bhargava Chandramohan

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 1848-1851

Background: Acute Kidney Injury (AKI) is the sudden loss of renal function. Multiple causes of AKI exist that include those that afflict the general population, and those that are associated with pregnancy. AKI in pregnancy is of particular challenge as there are physiological alterations of renal function in pregnancy. The diagnosis is by abnormalities of renal function tests in addition to the abnormalities reflecting underlying pathologies. Management depends on underlying causes and the prognosis can often be positive.
Material and methods: We present three cases of AKI in pregnancy, their evaluation and management.
Results: The first patient had AKI due to septic abortion and was treated by dialysis. The second patient had AKI due to preeclampsia with severe features and was treated by termination of pregnancy and multiple anti-hypertensives. The third patient had AKI due to hyperemesis gravidarum and was treated aggressively with fluids and anti-emetics.
Conclusion: Early recognition and initiation of appropriate therapy can lead to favourable outcomes in AKI.

A study on analysing the outcomes of maternal nutrition on infant's birth weight

Dr Ranjana Bhardwaj, Dr Vijay Bhardwaj, Dr. Meeta Agnihotri, Dr. S.K. Pathak

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 10293-10298

Background:Health & nutritional status of mother during & before pregnancy is
considered to be strongly associated with pregnancy outcomes. Poor nutritional status
& inadequate intake of food in pregnancy not only affect women’s health but also effect
birth weight & development of infant. The present study was conducting to analyse the
outcomes of maternal nutrition on infant's birth weight.
Material and methods: The present cross-sectional study was conducted among 350
pregnant women. Socio-demographic characteristics and obstetrics information of the
pregnant women were collected using pretested questionnaires. Anthropometric
measurements were carried out using appropriate measuring instruments. All statistical
analyses were performed using SPSS version 20. Multiple linear regressions analysis
was also performed to explore independent effects of maternal factors. A p value< 0.05
was considered to be significant.
Results: In this study, the mean weight and height of pregnant women were 63.25kg and
156.32cm, respectively. Overall, the mean pre-pregnancy BMI of the study participants
was 24.43kg/m2. The study also revealed that the mean weight gain of the mothers was
9.45kg, within the weight gain range of 4–16kg. The mean maternal hemoglobin level
was 11.76g/dL. Moreover, the mean total serum cholesterol level of the mothers was
187.32mg/dL. Maternal blood sample analysis also revealed that the mean total serum
protein level was 5.70g/dL, with 81.42% and 18.58% of women having total protein
level less than 6.7 g/dL and between 6.7 and 8.7 g/dL, respectively. In multivariate
linear regression analysis, birth weight was significantly associated with parity,
maternal BMI, weight gain during pregnancy, hemoglobin level.
Conclusion: The present study concluded that birth weight was significantly associated
with parity, maternal BMI, weight gain during pregnancy, hemoglobin level. Therefore,
nutritional status of the pregnant women should be improved to reduce the risk of low
birth weight.

Clinical Study of Maternal and Perinatal Outcome in Heart Disease Complicating Pregnancy at Tertiary Referral Center

Malathi Jonna, Akila B, VanajakshammaVelam

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 10371-10377

Background:Cardiac disease is an important cause of maternal mortality and morbidity
both in ante partum and postpartum period. The overall incidence of heart disease in
pregnancy is <1%. Objective of present study was to determine maternal outcome in
pregnant women with heart diseases in terms of fetal complication, maternal
complication and Mode of delivery. Aims: The aim of this study is to evaluate the
influence of biological factors inPerinatal Outcome in Heart Disease Complicating
Pregnancy.
Materials and Methods: This study wasconducted between January 2018 to
Decmber2021,ina tertiary care centre, SVIMS, Sri Padmavathi Medical college for
women. It is a retrospective observational study. Sample size is 55.
Results: In the present study, age distribution varied from 20-40 yrs. majority of women
(52.72%) are in the age group 20-25 years, followed by 23.63% in the age group of 26-30
years, 12.72% in the age group 31-35 years and 1.81% in the age group 36-40 years.
90.90% of cases are booked cases and 9.10% of cases are booked cases.
Conclusion: Preconceptional counselling, accurate risk assessment, regular antenatal
checkups,prevention, early recognition and aggressive treatment of complications
during pregnancy are crucial in reducing themorbidity. Surgical correction of the
cardiac lesion prior to pregnancy is associated with better pregnancy outcome.

Pregnancy Outcome in Thyroid Disorder -A Clinical Study

Neelima Varaganti, Himabindu Sangabathula, Anatalaxmi Porla

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 844-854

Background: The objectives is to Screening of all the antenatal pregnant women for
thyroid dysfunction, To study the maternal and fetal noutcome in pregnancy thyroid
dysfunction, To provide adequate treatment and there by reduce adverse outcome,
Follow up of cases six weeks post partum.
Materials and Methods: Prospective, observational study. 110 patients were included.
The study was conducted at Department of Obstetrics and Gynecology (OBG), Modern
Govt MaternityHopsital, Petlaburz attached to Osmania Medical College, Hyderabad,
Telangana, India during the period from 1st December 2019 to 30th June 2021.Mothers
attending for ante-natal check-up and having either a detected or documented thyroid
dysfunction. An Institutional Ethics Committee approval was obtained. Written
informed consent was obtained from all the study participants. The mothers during
their first visit were included for detailed history, clinical examination and blood
investigations as follows.
Results: No age related influence in the presence of thyroid dysfunction, there was no
statistical significance. it was observed that 68% of abortions were in primigravida, it
was found that with increase in gravida abortion rate was less. the mode od delivery
had no significant variations in both hypo/hyperthyroidism. it was noted that
subclinical hypothyrid and overt hypothroid cases resulted in more preterm deliveries
than hyperthyroid patients.the study showed no significance difference in newborn
thyroxine levels among thyroid dysfunction groups.
Conclusion: The study showed that thyroid dysfunction is more among the pregnant
women. Hypothyroidism is the major thyroid dysfunction among the antenatal women.
The women with thyroid dysfunction had more incidents of adverse outcomes of
pregnancy like increased abortion rates, caesarean deliveries on the mothers and
preterm babies and lbw on the newborn.

A study of insulin resistance in women with preeclampsia

Dr. G.S.Snigdha,Dr. Duggasani Padmaja, Dr .P. Saritha

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 57-64

Background: Preeclampsia isa state of insulin resistance. Insulin resistance features like
Hypertension, hyperinsulinemia, glucose intolerance, and lipid abnormalities are
associated with pregnancy-induced Hypertension.
Aimsandobjectivesofthestudy:
1. Tostudyinsulinresistanceinwomenwith pre-eclampsia.
2. TocompareandevaluatetheroleofmeasuringIR amongwomenwith
preeclampsiaandnormalpregnancy.
Methodology: AProspectiveandobservational one year study conducted in
GovernmentGeneralHospital.Kurnool. Atotalof 50Womenwith
preeclampsiaand50women withnormalpregnancy. Women were instructed for 12hrs
overnight fasting about 2ml of venous blood was collected in a
fluorideethylenediaminetetraacetic acid vial using proper aseptic precautions. Plasma
was separated by centrifugationand usedforestimationof
plasmaglucoseandplasmainsulinlevels. Values are presented as mean ± standard deviation
(SD) and the statistical analysis was done using SPSS 17.0software. Student’s unpaired ttest
was used for comparison of parameters between two groups. The p-value
oflessthan0.05was consideredas statistically significant.

A Comparative Study of Serum Creatinine, Serum Uric Acid and Blood Urea in Normal Pregnant and Pregnancy Induced Hypertensive Subject

Bonala Sharat Babu, Azmatulla Shaik, Naveed Altaf, Md. Siddique Ahmed Khan

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 1280-1285

Background: Standard assessment of renal function in pregnancy is by measurement of
serum creatinine concentration yet normal gestational ranges have not been established.
The aim of this systematic review was to define the difference in serum creatinine in a
healthy pregnancy compared with concentrations in non-pregnant women to facilitate
identification of abnormal kidney function in pregnancy.
Materials and Methods: The study was performed on 70 pregnant women. Out of which
35 women were pregnancy induced hypertensive and 35 were normal pregnant women.
Results: The result showed significantly high blood pressure (SBP-197.21±21.7 VS
187.28±8.69, DBP 124.36±9.41 VS 99.2±6.28) and Blood urea (42.31 ±7.81 mg% VS
41.30±9.29 mg%), serum creatinine (3.45 ±1.19 mg% VS 3.18±1.38 mg%), serum uric
acid level (9.89±3.16 mg% VS 7.34±0.9 mg%) in pregnancy induced hypertensive
women compares to normal pregnant women. In the present study, in pre-eclampsia,
there is elevation of serum uric acid and serum creatinine elevated values are
statistically significant.
Conclusion: There is a renal derangement of parameters in preeclampsia so it may be
advised to renal function test to confirm involvement of renal dysfunctions.
Measurement of renal function Test could be used as a biochemical indicator in
pregnancy induced hypertensive women.

Fetomaternal outcome of pregnancy with COVID-19

Dr. ChhaviBhomia,Dr. Neelima Shah, Dr. Prashant Shah, Dr. Vasudha Sawant

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 1, Pages 695-700

Objective: To study the Feto maternal outcome of Covid-19 in Pregnancy.
Methodology: This is a retrospective study done on 53 pregnant patients who tested positive
for SARS-CoV-2 and were delivered in D. Y. Patil Hospital, Kolhapur from April 2020 to
July 2020. Maternal and fetal characteristics and the outcome of Covid-19 infection in
pregnancy was studied.
Results: Among the 53 patients, 49 patients (92%) were asymptomatic. Remaining presented
with fever, sore throat, cough. 69% were primigravida and 30% were multigravida. 66%
underwent LSCS while 28% were delivered normally. In majority, LSCS was done for
oligohydramnios and fetal distress. All the patients were discharged after negative swab
report and no maternal death was reported. About 32% of neonates required NICU admission
for hyperbilirubinemia, pneumonia and sepsis. There was no neonatal death and none of the
neonates turned out to be positive for covid-19.
Conclusion: The severity of SARS-CoV-2 was seen to be mild to moderate in pregnant
women. Majority of the women infected with coronavirus disease were asymptomatic. The
risk of vertical transmission to the neonate was also found to be low. Oligohydramnios and
fetal distress were commonly seen in the patients, pointing towards the lack of antenatal
follow up visits due to restricted mobility in the covid era.

To study incidence of patients with recurrent pregnancy loss with respect to antenatal patient & to identify the various etiological factors

Dr. Krati Mehta, Dr. Vibhuti Thakur, Dr. Akanksha Thora, Dr. Nilesh Dalal

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 2582-2587

Background &Method: The present study was conducted with an aim to study incidence of patients with recurrent pregnancy loss with respect to antenatal patient &to identify the various etiological factorsin the Department of Obstetrics and Gynecology, M.G.M Medical College and M.Y Hospital, Indore. In this period 14564 antenatal patients were admitted both in routine and emergency hours of which 5660 were high risk pregnancies. 89 patients had recurrent pregnancy loss. Of these 62 patients selected. These patients were randomly selected including all age groups, parity, socioeconomic and educational status.

Study of Arterial Blood Gas, Acid Base Balance and its CorelationwithFetomaternal Outcome inPregnancy Induced Hypertention

Dr. Poorvi Gupta, Dr. Pooja Deodhar, Dr. Mohini Thakur

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 2962-2969

Background &Method: To evaluate the maternal outcomes through ABG index and its
influence on new-borns through Apgar scoring. Role of arterial blood gas values and their
implications to patient management.A total of 130 women with PIH syndrome were treated in
Department of Obstetrics and Gynaecology of IMCHRC, Indore, over a period of 12 months
Result:In this study, 66.10% PIH patients improved by conservative management, whereas
33.88% required ventilatory support of which 5.08% died on mechanical ventilation.
Amongst which maximum patients which succumbed showed decompensated metabolic
acidosis at 0 hr ABG.In this study, the mean pH value, PO2, HCO3 in severe PIH cases were
lower than the mild PIH cases, whereas the mean PCO2 and BE levels in severe PIH cases
were higher than the mild PIH cases. Therefore, with the exerbation of the disease,the
differences of indexes from normal values became larger.

Maternal serum alpha-feto-protein as a predictor of the pregnancy outcome

Dr Heena Mir, Dr Saima Sadiq, Dr Saba Musharaf

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 3028-3033

Background: Elevated levels of maternal serum alpha-fetoprotein are associated with pregnancy complicated by Pre-eclampsia, placental abruption, placental infections, chronic villositis, low birth weight and preterm labor. The present study investigated the possibility that maternal serum alpha-feto-protein can be used to predict the pregnancy outcome as a routine test.
Materials & Methods: 250 patients in the Postgraduate Department of Gynaecology and Obstetrics, Lalla Ded Hospital, Government Medical College Srinagar, over a period of one year were assessed for maternal serum alpha-fetoprotein by human serum by microplate immuno-enzymometric assay by EIA-AFP kit.
Results: Age group 20-23 years had 31, 24-27 years had 80, 28-31 years had 104 and 32-35 years had 35 patients. The mean of the maternal serum alphafeto protein (overall) was 65.32+33.95. The mean of the maternal serum alphafeto protein in pregnancies with normal outcome was 53.47+25.65. The mean of the maternal serum alphafeto protein in pregnancies with adverse outcome was 92.96+34.99. 4 (1.6%) patients out of 250 developed low- lying placenta. 2 out of 4 had raised values of maternal serum alpha-fetoprotein. 6 patients out of 250 had still birth. 4 out of 6 had raised values of maternal serum alpha-fetoprotein. 19 (7.6%) patients out of 250 had low birth weight babies. 18 had raised values of maternal serum alpha-fetoprotein. 12 (4.8%) patients out of 250 had intrauterine growth retardation (IUGR) of babies. 11 had raised values of maternal serum alpha-fetoprotein.
Conclusion: There is no relation between preterm rupture of membranes, low lying placenta and still birth with raised levels of maternal serum alpha-fetoprotein. It is easily done and is cost effective.

Assessment of severe acute maternal morbidity and associated maternal deaths in females admitted to hospital based setting

Dr Abhijeet Madhukar Patil, Dr Poonam Atul Patil .

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 1812-1818

Background: Severe acute maternal morbidity has long-term ill effects on socioeconomic
condition and health of the females including excessive financial burden post-treatment
which may last lifelong to the desertion of females after hysterectomy considering the
inability to reproduce.
Aims: The present clinical trial was carried out to assess the incidence and various causes
leading to SAMM. Also, the trial was aimed at factors associated with the instance of nearmiss
cases or SAMM.
Materials and Methods: 82 SAMM cases and 4 maternal deaths were evaluated based on
the WHO criteria. The data were maternal deaths, demographic data, complications
encountered, gestational age at the time of SAMM, SAMM event time from admission
time, ICU admission, and associated organ failure/dysfunction. The collected data were
subjected to statistical evaluation and the results were formulated.
Results: Maternal death resulted from abdominal pain in 75% (n=3) and breathlessness in
25% (n=1) female. The disorders associated with SAMM were surgical cause,
haemorrhage, hypertension, indirect causes, and medical conditions respectively in 1.21%
(n=1), 32.92% (n=27), 63.41% 9n=52), 2.43% (n=2), and 18.29% (n=15) females. The
etiology of 4 deaths was due to 50% (n=2) deaths each from cardiac and respiratory
etiology in females with the gestational age of 30.10±2.14 weeks and 25.7±1.3 years of age.
Near-miss cases were 34.14% (n=28) due to compromised transport facility.
Conclusion: The present study concludes that severe acute maternal morbidity affects
significant females and is the leading cause of maternal death. The most common factor
associated with SAMM is in the present study was hypertension leading to morbidity
followed by hemorrhage, whereas, leading causes for morbidity were respiratory and
cardiac causes.

Demographic profile and outcomes of pregnant patients admitted with Covid-19 infection in a tertiarycare hospital in Himachal Pradesh, Indiaduring the first wave

Dr.Sourya Kanti Das, Dr.Harharpreet Kaur, Dr.Savita Kapila

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 2356-2361

Aim: To determine the demographic profile of pregnant females with COVID-19 infection.
The outcome and prognosis in pregnant women with COVID-19 infection was also
evaluated.
Method and material:The study included 38 pregnant women with COVID-19 infection and
hospital admission for at least 24 hours. Cause of admission was classified as obstetric and
COVID-19-related. All the patients were COVID positive and were referred from other
centres/ hospital to this facility andwas admitted to this hospital for delivery. Primary
outcomes included maternal admission to intensive care unit (ICU), COVID-19 pneumonia,
maternal mortality. The information on socio-demographic factors, pre-gestational chronic
diseases (including cardiac, renal, endocrine, psychiatric, hematologic and autoimmune
disease, cancer and HIV)and mode of delivery was collected.
Results:The mean age of the patients was 28.8±6.2 years. The mode of delivery for
60.5%patients(23) was normal vaginal delivery and lower segmentcaesarean section in
39.5%(15) patients.94.7%(36) patients were asymptomatic in the present study. Maximum
patients in the present studywere hospitalized for 3-5 days.
Conclusion: COVID-19 infection was associated with higher rates of caesarean section in
pregnant women. However, COVID-19 cannot be considered as an indication for
caesareansectiondelivery. Patients with increased age have more days of hospitalization than
younger patient.

A Hospital Based Observational Study to Evaluate the Effect of Prelabour Body Mass Index on the Mode of Delivery

Dr. Ramdas Garg, Dr. Avantica Agarwal

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 2679-2684

Background: Pre-pregnancy obesity is strongly associated with certain pregnancy
complications and perinatal conditions. Placental structure and function are important
for maternal and fetal health both during and after pregnancy. The aim of this study to
evaluate the effect of prelabour body mass index on the mode of delivery.
Materials and Methods: An hospital-based prospective study involving pregnant women
at term (33-37 weeks) admitted to gynaecology ward in district hospital Dholpur,
Rajasthan, India during one-year period. A total of 120 cases in the age group of 18-40
years included in the study. Patients were classified into 3 categories based on their first
trimester BMI. Category I included normal women (BMI 20- 24.9 kg/m2), Category II
included overweight women (BMI 25-29.9 kg/m2) and detailed history and clinical
examination including general physical, obstetrical and systemic examinations.
Category III included obese women (BMI >30 kg/m2). Data were analysed statistically
by Chi-square test of the dependence of variables and a p-value of less than 0.05 was
considered as statistically significant.
Results: Under anthropometric parameters, the differences in mean age, mean weight,
mean height and mean BMI among the three categories women were statistically
significant (p<0.001**), In this study, it was observed that overweight and obese women
were slightly older and short in stature when compared with women with normal BMI.
There was increased incidence of antepartum complications in Category III women as
compared to Category II and Category I women. The difference in the onset of labour
as well as mode of delivery among the three categories was statistically significant
(p<0.05*).
Conclusion: As obesity is a modifiable risk factor all attempts should be made to
maintain a normal BMI in women of childbearing age. Pre–pregnancy counselling,
health programme and appropriate multidisciplinary management should be done.

Generalized Discoid Lupus Erythematosus (DLE) with Systemic Lupus Erythematosus (SLE) in Pregnancy: Case Report

Dr. Gardenia Akhyar; Dr. IrdawatyIzrul; Dr. SherlyBirawati

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 652-656

GENERALIZED DLE: Patients with generalized discoid lupus erythematosus are at a higher risk of progressing to systemic disease than those with a localized variant. Pregnancy is one of the factors that can trigger lupus erythematosus. There are only one case report published in online search that presented generalized discoid lupus erythematosus in pregnancy. We report a case of 24 year old female patient with 31-32 weeks of gestational age complained blackreddish patches accompanied by fine scales, slightly itchy and a little painful on the forehead,
cheeks, bridge of the nose, chin, ears, neck, chest, stomach, back, upper and lower extremities since ± 2 months before. ANA profile with positive result. The results of histopathologicaland dermoscopyexamination suitable with discoid lupus erythematosus. Results of the internal medicine department revealed a diagnosis of systemic lupus erythematosus. CONCLUSION:Management of DLE aims to improve general condition of patient, control the lesions, prevent of the development of further lesions; fetal growth abnormalities; preterm birth; neonatal lupus and fetal death.

Maternal and perinatal outcomes of pandemic Covid-19 in pregnancy in Basrah

Maysoon Sharief, C.A.B.O.G.; Gufran Jaafar, C.A.B.O.G.,; Alla Hussan, M. B. Ch. B., D.O.G

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 517-529

To evaluate the maternal, fetal and neonatal complications in pregnant women with Covid-19 infection. Setting and design: A prospective descriptive study was carried out in Basrah Teaching Hospital, Iraq during the period 15/3/2020 till 1/11/2020. There were 135 infected pregnant women with Covid-19. The maternal information's were obtained included Age, parity, residence, travel history, gestational age at time of diagnosis. The pregnancy measures of interest were evaluated according to the severity of the disease, medical disease, history of antepartum hemorrhage, mode of delivery, type of delivery, post-natal complication and admission to
intensive care unit and maternal death. The neonatal outcomes of interest were fetal weight, neonatal Apgar
score, admission to neonatal intensive care unit and neonatal death. Results: The mild type of the disease was common (41.48%) in comparison to severe conditions (17.77%).

Hemodynamic indicators in pregnant women with obesity of various degrees of expression

Matlubov Mansur Muratovich; Muminov Abdukhalim Abduvakil; Khamdamova Eleonora Gafarovna; Yusupov Jasur Tolibovich

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 2, Pages 2373-2380

Purpose: To study indicators of central and peripheral hemodynamics in pregnant women with obesity of varying severity at a gestational age of 36-38 weeks.
Materials and Methods: To study hemodynamic parameters (heart rate, SDD, UI, SI, OPSS, CR, LVMI) in pregnant women with obesity of varying severity, 127 pregnant women (I, main group) aged from 23 to 34 years were selected obesity of varying severity with gestational age 36-38 weeks. The second (control) group consisted of 28 pregnant women of the same age and gestational age with normal body weight (body mass index from 19 to 24.9 kg / m2). The groups were identical in age, gestational age, which allowed for an objective and comparative assessment.

Family Empowerment Model on Early Detection Ability Of High risk Pregnancy

Ika Mardiyanti; Nursalam Nursalam; Shrimarti Rukmini Devy; Ernawati .

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 10, Pages 1111-1131

There are still many pregnant women and their families who are unable to do early detection of high risk pregnancies. The purpose of this study was to develop a family empowerment model for the early detection ability of high-risk pregnancies.An explanatory survey research with a cross sectional study approach. The study population was the family of pregnant women in the Surabaya area who were taken using the rule of thumb with a sample size of 120 respondents using systematic random sampling. The latent variables in this study are personal factors, cognitive behavior, resource factors, interpersonal, basic values (Fillial Values), commitment, and family ability in early detection of high risk pregnancies, as measured by using a questionnaire. Latent variables that affect family empowerment consist of data analysis using Structural Equation Modeling (SEM) -Partial Least Squares (PLS).The results showed that the family empowerment model for the early detection ability of high-risk pregnancy was a fit model. This refers to the results of the goodness of fit test. Personal factors towards interpersonal (T statistics = 10,301; P = 0,000), interpersonal towards Fillial Value (T statistics = 13,501; P = 0,000), Fillial Value for commitment (T statistics = 9,495; P = 0,000), family commitment to early detection ability of high risk pregnancy (T statistics = 3,840; P = 0,000).The results of this study provide information about family empowerment models in high-risk pregnancies so that they can be used as a reference in preparing midwifery care plans in cases of maternal emergencies for high-risk pregnant women.

Food Security And Household Expenditure Impact On Nutritional Status On Pregnancy: A Cross Sectional Study In Rural Area

Ratna DewiPuspita Sari; Sutyarso .; Samsul Bakri; DyahWulanSumekar RW; Mentari Olivia F.; Arli Suryawinata; Tisa Mahdiansari

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 4719-4726

Purpose:This study was aimed to analyze the correlation of food security status and household food expenditure to nutritional status on pregnant women.
Research Methodology:This study was an observational study with crossectional design, conducted in PuskesmasWonosobo, Lampung Province, Indonesia on May 2020 - Augustus 2020. All of pregnant women who get Antenatal Care (ANC) on Puskesmas were carried out as samples. Food security status and household food expenditure data were measure by anamnesis and questionnaire. Nutritional status was asses by mid-upper arm circumference (MUAC) of pregnant women. Data was collected and then analyzed using SPSS 21 application.
Results:A total of 53 pregnant women, with age distribution on range of <18 years &>35 years (20 women) and 20-35 years (33 women) were analyzed in this study. Statistical analysis (Chi-Square) show the pregnant womens in malnutrition status with food insecurity were 3 women (75%) while pregnant women in good nutrition status with food insecurity only 3 women (6.1%) (p = 0.003). Correlation between house hold expenditure to nutritional status was analyzed by chi-square test, the result show all of pregnant women in malnutrition status (4 women) have lower house hold expenditure (p = 0.001).
Conclusion:This study clearly shows that more food security and level of household food expenditure will affect on nutritional status of pregnant women.

FORECASTING EPILEPSY RISK IN CHILDREN BORN FROM PARENTS WITH EPILEPSY

Muslima Mambetkarimova; Dilfuza Ashurova; Yakutkhon Madjidova; Nadira Zakirova; Sherali Ergashev

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2375-2381

This article details the condition of newborn babies from mothers with epilepsy.
The frequency and nature of epilepsy in children born to mothers with epilepsy are
described. Risk factors for the development of epilepsy in children born to mothers with
epilepsy were determined.

Qualitative Study On Mother’s Experiences For Self-Management Of Gestational Gestational Diabetes Mellitus

Mufdlilah .; Aseel Abdulameer Mohammed; Rolita Efriani; Dewi Rokhanawati; Nur Rachman Dzakiyullah

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 70-78

Background:Gestational diabetes mellitus (GDM) becomes common cases over the globe. GDM prevalence is counted as 1-3% out of all pregnancies in the west and 90% of them are complicated by diabetes. GDM is related with the increasing of maternal risk and short-time or long-term perinatal complication.GDM incidents in Indonesia are identified around 1,9-3,6% and around 40-60% women, who ever experienced with GDM, on the further observation after labouring will have diabtes melitus or glucose tolerance disorder. This research is aimed to identify the mother’s experience in GDM self-management.
Methods: This research is a qualitative research with phenomenology approach. This research was conducted on October 2018 – June 2019. The data were collected by employing interview that supported by documentation study over 8 mothers who had GDM interview and 3 midwives in charge at the KIA poly service. The data were analyzed by using thematic analysis.
Results: Qualitative analysis resulted five themes that cover nutrition management, education, glucose monitoring, sports and medication. The results showed that pregnancy mother tried to control the eating pattern as suggested by the health-workers. The mothers should conduct routine glucose controlling, perform physical activity, such as regular walk, perform house works or pregnancy workout. The appropriate medication during the pregnancy involves insulin.
Conclusion: This research reveals mothers’ experiences in GDM self-management in terms of lifestyle. The result of the research could be a valuable guidance in developing comprehensive self-management service, by considering more on mother’s self-management. The necessities of more effective GDM counceling is required to ensure clear understanding about principal self-management for pregnant mothers, hence it could help mother in enhancing adaptation and ability in dealing with GDM. Besides, it could increase the alert towards the risks on pregnancy with diabetes mellitus. Hence screening examination on diabetes melitus.
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This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self -management.management.management.management. management.management.management.management.Methods: Methods: This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. 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The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis.Results:Results:Results: Results: Results: Qualitative analysis resulted Qualitative analysis resultedQualitative analysis resultedQualitative analysis resulted Qualitative analysis resultedQualitative analysis resultedQualitative analysis resultedQualitative analysis resulted Qualitative analysis resulted Qualitative analysis resultedQualitative analysis resultedQualitative analysis resulted Qualitative analysis resulted Qualitative analysis resultedQualitative analysis resulted five themes five themesfive themesfive themes five themesfive themesfive themesfive themes that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy mother tried mother tried mother tried mother tried mother tried mother tried mother tried mother tried mother tried to control the eating to control the eating to control the eating to control the eating to control the eating to control the eating to control the eating to control the eating to control the eating to control the eating to control the eating to control the eating pattern as suggested by the health pattern as suggested by the healthpattern as suggested by the health pattern as suggested by the healthpattern as suggested by the health pattern as suggested by the health pattern as suggested by the health pattern as suggested by the health pattern as suggested by the health pattern as suggested by the healthpattern as suggested by the health pattern as suggested by the healthpattern as suggested by the healthpattern as suggested by the healthpattern as suggested by the healthpattern as suggested by the health pattern as suggested by the health-workers. The mothers workers. The mothers workers. The mothers workers. The mothers workers. The mothers workers. The mothers workers. The mothers workers. The mothers workers. The mothers workers. The mothers workers. The mothers should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin.Conclusion:Conclusion: Conclusion:Conclusion: Conclusion: Conclusion:Conclusion: This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self -management in termmanagement in term management in term management in termmanagement in termmanagement in termmanagement in term management in termmanagement in term s of lifestyle. of lifestyle. of lifestyle. of lifestyle. of lifestyle. of lifestyle. The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing comprehensive selfcomprehensive self comprehensive self comprehensive selfcomprehensive selfcomprehensive selfcomprehensive selfcomprehensive self comprehensive selfcomprehensive self comprehensive self -management service, by considering more on mother’s self management service, by considering more on mother’s self management service, by considering more on mother’s self management service, by considering more on mother’s self management service, by considering more on mother’s self management service, by considering more on mother’s self management service, by considering more on mother’s self management service, by considering more on mother’s self management service, by considering more on mother’s self management service, by considering more on mother’s self management service, by considering more on mother’s self management service, by considering more on mother’s self management service, by considering more on mother’s self management service, by considering more on mother’s self management service, by considering more on mother’s self management service, by considering more on mother’s self 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considering more on mother’s self -management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear underunderunder understanding about principal self standing about principal selfstanding about principal selfstanding about principal self standing about principal self standing about principal self standing about principal self standing about principal self standing about principal selfstanding about principal selfstanding about principal self standing about principal selfstanding about principal self standing about principal self -management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM. 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Besides, it could increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with increase the alert towards risks on pregnancy with diabetes mellitus diabetes mellitus diabetes mellitusdiabetes mellitusdiabetes mellitus diabetes mellitus diabetes mellitusdiabetes mellitus. Hence screening Hence screening Hence screening Hence screening Hence screening Hence screening Hence screening Hence screening Hence screening Hence screening examination on xamination on xamination on xamination on xamination on xamination on xamination on xamination on diabetes melitus. diabetes melitus. diabetes melitus.diabetes melitus. diabetes melitus.diabetes melitus.diabetes

Maternal Health Study In Province Lampung Based On Prediction Model Structural Equation Modeling-Partial Least Square

Ratna DewiPuspita Sari; Sutyarso .; Samsul Bakri; DyahWulanSumekar RW; Arli Suryawinata; Mentari Olivia F.; Tisa Mahdiansari

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 4727-4735

Purpose:This study was aimed to analyze the correlation of food security status and household food expenditure to nutritional status on pregnant women.This study was aimed to identify the significant effect of the determinants factor of maternal health and incidence of maternal death.
Research Methodology:This study was an observational study with cross sectional design, Thisstudy was conducted in Province Lampung, Indonesia, in 2020. Population of this research consisted of situation maternal health in provience Lampung. Sampel in this study are report of bacis health and SDGs series: districts/city readiness from 13 districts and 2 cities in Province Lampung. The studied indicators either were evaluated of environtment, health behavior, and health service for ech districts/city. Data was collected and then analyzed using SmartPLS application.
Results:The environment determinant in this study was determined to water quality and sanitation. Health behaviour determinant indicator was assessed by ANC adherence and labor operator while indicator of health service determinants were access of health service, care of maternal complication, health insurance. All of determinants have significant correlation to maternal health by T- value and p value were (T= 2.201 ; p= 0.028), (T= 2.467 ; p= 0.012), (T=2.737 ; p=0.006), respectively dor environment, health behaviour, and health service determinants. Refer to the result above which are schematized in Figure 1, it can be learned that environment, health behavior and health services present strong effets to maternal health.
Conclusion:This study results show clearly there are correlation of variable determinants; environment, health behavior, and health service to affect maternal healthby the pathways.

PREVALENCE AND RISK FACTORS OF DENTAL DISEASES IN PREGNANT WOMEN LIVING IN DIFFERENT REGIONS OF UZBEKISTAN

Suvonov K.J .; Adilov U.X .; Kuryazov A.K.

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2863-2870

The aim was to study the prevalence and risk factors of dental disease development in
pregnant women living in different Uzbekistan regions. The prevalence and intensity of dental
caries among pregnant women are 1.3 times higher in the Urgenchdistrict of the Khorezm
region compared to the Kibray district of the Tashkent region. These figures increase with
each subsequent pregnancy. The same pattern is observed for periodontal and oral mucosa
diseases. The most significant medical and biological factors contributing to the development
of dental diseases in pregnant women were age, several pregnancies, intergenerational period,
course and terms of pregnancy, the presence of extragenital diseases. Among medical and
social risk factors, the most significant were education, living conditions, oral hygiene,
sanitary culture, and medical activity of pregnant women.

Subclinical Hypothyroidism in Pregnancy: A Review

Dr. Ritimukta Panda; Dr. Kavya Sudha; Dr. K.Jaya Sri; Dr. Rachita Sarangi; Dr. Bhagirathi Kar; Dr. Gangadhar Sahoo

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 6, Pages 1443-1446

Pregnancy-reference levels of Subclinic hypothyroidism (SCH), along with normal level of serum thyroxine, are called high thyroid stimulation hormone level (TSH).
Autoimmune Thyroiditis is also common in patients of subclinical hypothyroidism. Subclinical Hypothyroidism in pregnancy is the cause of some adverse obstetric consequences. Changes in the metabolism of thyroid hormones during pregnancy needs to be kept in mind, while diagnosing thyroid abnormalities. There is a jump in the obstetric and neonatal results, like preterm delivery, miscarriage, fetal growth restriction, preeclampsia, gestational diabetes mellitus, low birth weight, abruptio placentae and poor Apgar scores at birth. Treatment with Cevothyroxine therapy may help reduce some of these adverse effects, however there is restricted evidence to provision it. The behavior of subclinical hypothyroidism should target maternal TSH concentrations of less than 2.5mIU/L. However there is a lack of recommendation for the official starting dose of levothyroxine. So, individualised low doses of levothyroxine can be started and thereafter titred to the maintain the TSH in the target level

A COMPARATIVE STUDY OF THE EFFECT OF ORAL AMINO ACID SUPPLEMENTATION VS INTRAVENOUS AMINO ACID INFUSION ON AMNIOTIC FLUID INDEX AND PERINATAL OUTCOME IN PREGNANCIES COMPLICATED BY OLIGOHYDRAMNIOS AND FOETAL GROWTH RESTRICTION

Dr. AKRUTI SHINDE; Dr. MEHUL SALVE

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 2018-2026

BACKGROUND: The primary function of amniotic fluid is protection of the growing foetus while providing nutrition. A considerable amount of research has been conducted to evaluate interventions to improve amniotic fluid index and the subsequent impact on foetal growth restriction and oligohydramnios. However, there isn't any conclusive evidence hence this study aims to compare the effect of oral amino acid supplements and intravenous infusions in pregnancies with oligohydramnios and foetal growth restriction. 
AIM: To compare the effect of oral amino acid supplementation vs intravenous amino acid infusion on amniotic fluid index and perinatal outcome in pregnancy complicated by oligohydramnios and foetal growth restriction
OBJECTIVES: To compare the effectiveness of oral amino acid supplementation vs intravenous amino acid infusion in pregnancy having oligohydramnios and foetal growth restriction. To study the increase in amniotic fluid index in pregnancy with foetal weight gain. To study the interval growth rate of baby after two weeks and four weeks of therapy.
MATERIAL AND METHOD: This Semi experimental study will be conducted in Department of Obstetrics and Gynaecology, AVBRH, Datta Meghe Institute of Medical Sciences, Sawangi (Meghe), Wardha. A total of 104 clinically and sonographically proven cases of foetal growth restriction & Oligohydramnios in third trimester attending antenatal clinic or admitted in wards, fulfilling the exclusion and inclusion criteria will be comprise the study groups. After providing oral supplements or intravenous infusions arbitrarily, repeat ultrasonography will be done after two weeks and four weeks of therapy.
EXPECTED RESULTS: We compare from our results the effect of oral amino acid supplementation vs intravenous amino acid infusion on amniotic fluid index and perinatal outcome in pregnancies complicated by oligohydramnios and foetal growth restriction.

Clinical Profile of Pregnant Patients With Acute Kidney Injury; Single Center Study

Ahmed Noaman Elsayed; Amir Mohammed Elokely; Mohammed Fouad Ahmed; Tareq M. Elbehedy

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 6881-6889

Background: A sudden decline of renal function occurring during pregnancy or postpartum is defined as Pregnancy-related acute kidney injury (PRAKI) includes all the causes not only the obstetric one. The incidence and etiology of PRAKI varies greatly between different regions. Data for the prevalence and prognosis cannot be interpreted without taking into account the geographic and economic context of the country in which they have been obtained. In developed countries, obstetric AKI has become a rare complication of pregnancy. However, in developing countries, AKI remains a frequent and grave complication of pregnancy. Aim: to demonstrate the demographic, clinical and laboratory characteristic of the pregnant women with AKI. Materials and Methods: A Cross-sectional study was carried out among pregnant women who were admitted to obstetrics & gynecology department in collaboration with nephrology unit in internal medicine department during a six months. This study is a part of a large study on the prevalence and outcome of AKI in pregnancy by the same authors in the same center that will be published soon. The demographic, clinical and laboratory data was obtained and analyzed
Results: During the period of the study, a total of 4130 obstetric cases were admitted to the hospital. In total, 33 patients met the diagnostic criteria of pregnancy related acute kidney injury. The mean age of the patients was 29 ± 4.58 years, and gestational age was 31.46 ± 6.34 weeks. Eleven of the 33 women (21%) were primiparous and twelve of them (79%) were multipara. There was a significant findings between the patients who were suffering from hypertensive disorders of pregnancy (Group 1) and who didn’t suffer (Group 2) as regarding low hemoglobin level and low arterial blood pressure and in group 2, while group 1 showed higher uric acid level and low albumin level with a significant finding.

The Relationship Between Child Infant Mortality And Air Pollution

Rabab Hajwal Al-Zamily

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 17-25

Objectives: This paper points to verify the influences of motherly exposure the basic air depressions off infant mortality. For further investigation of these relationships, we used vital registry data to retroactively build (2907) deaths occurred between 2009 and 2013 at Children's Medical City Hospital for children younger than one year and (1167) of them less than a month Previous investigates have concerned air contamination in raised mortality and disease, mainly in the aged populace and childish person. Extra in recent times, relations with death in newborns then through several generative reproductive effects have also been registered
The purpose from such study is to analysis the relationship relating revealing to open-air pollution for the period of gestation then infant mortality, airborne contamination is linked to poor pregnancy.
Elevation indication has exposed that population’s physical and mental health be able to be influenced air study by several contaminations.
Then, this investigate
Purposes to examine the correlate between air pollutions (O3, SO2, NO2, CO, Pb, PM2.5 or PM10) and Born prematurely. For the interval period (2009-2013).
Method: Totally Infant mortality information besides child birth information since (first January 2009 to end December 2013) be there recorded Children’s Hospital in Medical City in Baghdad Iraq
And Daily data on air quality from The Iraqi Ministry of Health and the Environment, The reality of the environment report (2010 ...) report on the status of the status of the Iraqi Environment

Retrospective analysis of the birth histories of women who have suffered bleeding in order to optimize approaches to the prediction and prevention of postpartum bleeding

Poyonov O. Yoldoshevich; Karimova N. Nabidjanovna

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 6236-6243

The aim of our study was to retrospectively examine the history of childbirth and the quality of primary care for bleeding and evaluate the prescribed rehabilitation measures for women who have suffered postpartum hemorrhage and massive bleeding. The materials and methods of the study were 242 birth histories with postpartum hemorrhage for the last 6 years (2013-2018) in the city maternity hospital of Bukhara. The average age of the patients was 26.7 ± 1.2 years. The obstetric pathology leading to bleeding mainly consists of uterus hypotonia - 143 (59.1) and large fetus - 68 (28.1), and preeclampsia and DIOV are equal amounts - 33 (13.64). Only about 20% of women who had postpartum hemorrhage underwent early rehabilitation in the form of prescribing contraceptives.The aim of the research was to study the effectiveness of modern principles of stopping postpartum obstetric bleeding. From 127 cases of bleeding in 101 women (79.5%) the childbirth were with the operational method. With the development of blood loss was renderedstepwise ways to stop bleeding. During hemostasis of the bleeding, ligatures were imposed on the ovarian arteries and the ascending branch of the uterine artery for ischemicization of the uterus, which was effective in 30 (30%) women, and in 114 (89.7%) women managed to achieve organ-sparing tactics.

Features of perinatal outcomes in women after supporting reproductive technologies

Shakhnoza F. Bakhodirova; Gulchekhra A. Ikhtiyarova; Aslonova M.J .; Salim S. Davlatov

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 6350-6356

Pregnancy conceived with assisted reproductive technologies (ART) has a higher risk of maternal and perinatal complications, and the overall risk of adverse outcomes requiring extended obstetric care has not been thoroughly studied. The review is devoted to the actual problem of the health status of children born after IVF. A systematic review of the health indicators of children conceived with IVF after the neonatal period was carried out versus natural, conceived.

DEVELOPMENT OF PRE-ECLAMPSIA IN PREGNANT WOMEN WITH OBESITY

Zulfiya Shamsieva; Yusupbaev R.B.

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2450-2454

Abstract. The aim of this study was to examine the impact of obesity in pregnant women in
the development of preeclampsia. All women were divided into 2 groups: the study group
included women with obesity (n=120) and the control group of pregnant women with
physiological course of pregnancy without obesity (n=60).

SOLUTIONS MICRONUTRIENTVITAMINS DEFICIENCY IN LOW BIRTH WEIGHT INFANTS

Nigora Ahrarova; Marguba , Umarov; Zilola Sharipova; Aziza Saidova; Iroda Khodjaeva

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2410-2418

Abstract. Insufficient supply of pregnant women with micronutrients leads to the
development of a number of congenital malformations of the fetus. In order to study the
multivitamin-mineral complexes application’s effect on pregnant women during
pregnancy, and on intrauterine fetal growth and development. Was revealed that a
deficiency of bioelements and vitamins in mothers is a common cause of intrauterine
growth retardation, serious violations of organs and systems functioning. So, it is indicates
integrated approach significance in the treatment of microelementosis in pregnant.

RELATION BETWEEN EARLY PREGNANCY BMI AND GESTATIONAL WEIGHT GAIN WITH NEONATAL BIRTH WEIGHT

N. S. Kshirsagar; Supriya patil; M. M. ladded; S.S. Vhalwal; Archna V. Rokade

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 4130-4135

Study objective is to study the influence of early pregnancy BMI on neonatal birth weight. To Study the association between gestational weight gain and neonatal birth weight. An observational correlational study, consisting of 1031 pregnant women, with singleton uncomplicated pregnancy, booked at Krishna Institute of Medical Sciences, Karad before 12 weeks of pregnancy, conducted between June 2014 to December 2015. After getting written informed consent from the patient, patients included in the study. Those who developed any complication during the study were excluded. With rising BMI, weight gain in pregnancy is greatly increased. Maternal pregnancy BMI has a positive association with the birth weight of neonatal. Lower BMI is significantly linked to a relatively low weight gain lower birth weight.

ORAL NIFEDIPINE VERSUS ORAL LABETALOL IN THE TREATMENT OF PREGNANCY INDUCED HYPERTENSION

R.P. Patange; Archna V. Rokadhe; Ghori R. Shinde; Sanjay N. Jadhav; Ashitosh Bahulekar

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 4136-4141

This study was undertaken to determine the effectiveness of two anti-hypertensive drugs: oral Nifedipine and oral Labetalol in cases of extreme preeclampsia in terms of their side effect profile, BP regulation, time taken to lower BP, and number of doses required. The objective of the study was to calculate the time required to reduce the blood pressure to the target level of 90 / 100 mmHg diastolic and less than 160mmHg systolic.In the labetalol group the mean SBP before treatment was 158mm of Hg which was reduced to 140 mm of Hg. The decline rate in the labetalol group was 11.77%. This study proved that labetalol reduces the BP more effectively than nifedipine and also has minimal side effects with less frequent dosing schedule as compared to nifedipine thus indicating that labetalol is better than nifedipine in lowering the BP in cases of preeclampsia.

Epidemiological study of COVID-19 pneumonia in pregnant woman and their neonates; report of thirteen confirmed COVID-19 pregnant women

Alireza Kamali; Behnam Mahmodiyeh; Amir Almasi-Hashiani; Morteza Mousavi Hasanzadeh; Maryam Shokrpour

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 4455-4461

Background: In new pandemic, the probable effects of COVID-19 pneumonia on pregnant woman and their infant is one of new critical challenge for health care. Here we presented clinical symptoms, laboratory findings and outcome of COVID-19 pneumonia in pregnant woman. Methods: In a case series study, from 15 Feb to 15 June 2020, all women with RT-PCR COVID-19 who referred to two hospitals (Taleghani and Qods Hospital) affiliated to Arak University of Medical Sciences were selected. The epidemiological and demographic variables, laboratory test and outcomes obtained from patient’s medical records. Results: In this case series, we presented thirteen confirmed COVID-19 pregnant women. Their mean age was 34.6 (S.D.: 5.9) years and the mean gestational age was 32.4 (S.D.: 7.3) weeks. Most of patient didn’t show any maternal complication and intrauterine vertical transmission. The large number of pregnant women had normal HRCT and also in terms of laboratory most of the patients had normal laboratory tests. Amniotic fluids, cord blood, the throat swab of neonate in our pregnant woman with delivery were tested for COVID-19 and all of them were negative. Conclusion: The COVID-19 mothers and their infant didn’t have higher risk for morbidity and mortality and this virus didn’t associate with intrauterine vertical transmission.