Keywords : Association of IOP with Duration of Diabetes
Effect and Relationship of Duration of Diabetes with Intra Ocular Pressure in Adults of Kashmir. A Study from a Tertiary Care Centre in North India
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 8, Pages 1709-1714
Each year, about 1% of all individuals with increased IOP progress to glaucomatous damage. Elevated IOP level is a major risk factor for the development and progression of Primary open-angle glaucoma (POAG) and lowering the IOP in patients suffering from POAG slows up the disease progression. Therefore, potential risk factors for POAG need to be identified so that interventions are developed to reduce its incidence. It is postulated that damage to the microvasculature network and/or decreased nutritional supply to retinal ganglion cells (RGCs) axons is due to interference of blood regulation in optic nerve head area. This nutritional deficiency may lead to degeneration of RGCs and start glaucomatous impairment. Hence, any vascular related systemic disease, such as diabetes, which directly or indirectly disrupts nutritional supply to RGCs, may result in development of POAG. The study design involved 360 subjects, and were categorized into two groups, namely: Group A: This was an experimental group comprised of Diagnosed Type-2 Diabetic patients. Group B:This was a healthy controlled group, non diabetic (n-150). which were compared with Group A on similar parameters .Tonometry with Applanation tonometer was done which measures fluid pressure (IOP) in eyes. Our results showed that Increased IOP is significantly associated with duration of diabetes. With the increase in duration of diabetes intraocular pressure also rises with high IOP seen with duration more than 12 years. This was found to be true for their both eyes. Due to Lack of proper control of diabetes different parts of the body especially the eyes are exposed to the destructive effects of diabetes and hence impair their functioning.