Online ISSN: 2515-8260

Keywords : Rickets


A RETROSPECTIVE STUDY ON IMPACT OF COVID PANDEMIC ON VITAMIN D LEVELS IN CHILDREN AGED 6 MONTHS TO 12 YEARS IN POST COVID ERA

Dr Manoj Kumar Patil, Dr Meghna Khetan, Dr Supriya Gupte, Dr Sampada Tambolkar, Dr Shradha Salunkhe, Dr Sharad Agarkhedkar

European Journal of Molecular & Clinical Medicine, 2023, Volume 10, Issue 1, Pages 1508-1517

Study title:  A retrospective study on impact of covid pandemic on vitamin D levels in children aged 6 months to 12 yearsin post covid era
Aims: To determine the severity of deficiency and the presenting features
Introduction: Vitamin D insufficiency affects almost 50% of the population worldwide. An estimated 1 billion people worldwide, across all ethnicities and age groups, have a vitamin D deficiency (VDD). This pandemic of hypovitaminosis D can mainly be attributed to lifestyle and environmental factors that reduce exposure to sunlight, which is required for ultraviolet-B (UVB)-induced vitamin D production in the skin. The high prevalence of vitamin D insufficiency is a particularly important public health issue because hypovitaminosis D is an independent risk factor for total mortality in the general population. Many health care providers have increased their recommendations for vitamin D supplementation to at least 1000 IU.
 
Methodology: this study was done over a span of 10 months from September 2021 to July 2022
This was a retrospective descriptive study in which data were recorded for all patients aged from 6 months to 12 years of age with features suggestive of vitamin D deficiency seen in Dr DY Patil Medical College and Hospital, Pune for a period of 10 months
The Health Research and ethics committee of Dr DY Patil Medical College and Hospital, Pune approved the study and waived the requirement for the informed consent. A total of 69 patients were included in this study.
Results: 69 patients were included in the study out of which 39 were males { 56.52%} and 30 were females { 43.48%} . the main presenting feature was bowing of legs { 31.9%} followed by difficulty in walking in 15.9%
Out of 69 children 53 had severe deficiency, 13 had mild to moderate deficiency and 3 had optimum levels of vitamin D.
28 children belonged to the age group of 1-5 years followed by 18 children in age group of 5-10 years and 11 children in age group less than 1 year and 10-15 years
Out of the entire study group 56 children had bony deformities and 13 had neurodevelopmental presentation
Conclusion:  the above results emphasise the fact that due to covid most of the children were restricted to stay indoors for several months leading to vitamin D deficiency in them. it also emphasis the fact that regular screening of children should be done with respect to vitamin D levels and also other micronutrients and children should be encouraged to have some amount of sun exposure to get natural supplementation of vitamin D and also be supplemented at desired intervals so that they adequate amount of vitamin D levels.

STUDY OF VITAMIN D IN CHILDRENS UPTO THE AGE OF 18 YEARS

Dr Haseeb Ul Haq ,Dr Raghunath S.V, Dr Sushma.V

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 2876-2881

Objectives:1) To determine the Vitamin D in children up to age of 18 years
Methods: A prospective observational study was done from June 2019-Feb 2020 from 0 to 18 years of children’s
Results: Severe Vitamin D deficiency may cause rickets in infants and children However, subclinical vitamin D deficiency is more prevalent, and it is associated with falls or frac­tures. It has been observed that maximum children with rickets were breastfed, breast milk contains less vitamin D
Conclusion: Vitamin D is an essential nutrient not only important in bone health but also beneficial to many other systems. Therefore, Pediatricians should provide information to patients who are at higher risk for vitamin D deficiency on how to get sufficient dietary or supplemental vitamin D.

Criteria for studying the risk factors for rickets and its effect on the level of 25 (OH) D in blood serum in children

Rasulova Nadira Alisherovna; Rasulov Alisher Sobirovich; Sharipov Rustam Xaitovich; Axmedova Maxbuba Maxmudovna; Irbutaeva Lola Tashbekovna

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 2, Pages 2150-2153

Based on questionnaires and level of 25(OH)D in 466 children under 1 year factors for rickets was identified. Reliable factors were iron deficiency anemia during pregnancy, toxemia of pregnancy of the mother and the lack of vitamin D during first year of life of a child, lack of outdoor stay (less then 20 minutes per day), frequent colds, not effective traditional prevention of rickets vitamin D.

EFFICIENCY OF COMBINED APPLICATION OF APRICOT OIL AND AEVIT AS A REGULATOR OF LIPASE ACTIVITY OF BLOOD SERUM IN CHILDREN WITH VITAMIN D-DEFICIENCY RICKETS

Sh.M. Ibatova; F.Kh. Mamatkulova; D.S. Islamova

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 787-796

In children with rickets, significant changes in the composition of higher fatty acids in blood serum have been established by gas-liquid chromatography. The depth of changes in the composition of higher fatty acids depended on the severity of the disease. The violated composition of higher fatty acids was corrected using vegetable (apricot) oil and aevit. Apricot oil helps to normalize the activity of serum lipase and leads to the restoration of the metabolism of higher fatty acids, the absorption of calcium and phosphorus thereby ensures high efficiency of therapy in children with vitamin D-deficient rickets. The effectiveness of this method of treating children before traditional therapy is shown.

Criteria for studying the risk factors for rickets and its effect on the level of 25 (OH) D in blood serum in children

Rasulova Nadira Alisherovna; Rasulov Alisher Sobirovich; Sharipov Rustam Xaitovich; Axmedova Maxbuba Maxmudovna; Irbutaeva Lola Tashbekovna

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 1730-1733

Based on questionnaires and level of 25(OH)D in 466 children under 1 year factors for rickets was
identified. Reliable factors were iron deficiency anemia during pregnancy, toxemia of pregnancy of the mother and the lack of vitamin D during first year of life of a child, lack of outdoor stay (less then 20 minutes per day), frequent colds, not effective traditional prevention of rickets vitamin D.