Online ISSN: 2515-8260

Keywords : resistance


DSc. Kurbonov A.Y .; prof.Avtonomov V.A .; prof. Axunov A.A .; DSc.HashimovaN .

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 1044-1051

In the world's cotton-growing countries, cotton is cultivated on the territory of 89 countries, on a total area of more than 30 million hectares, from which more than 22.4 million tons of cotton fiber are obtained. Today, there are problems in the production of high-quality cotton fiber yield. One of these problems is pathogens that cause significant damage to cotton production, with losses in the world amounting to 12-15%. In the world, considerable attention is paid to the study and control of the pathogen Verticillium dahliae Klebahn, which affects cotton.
The problem of breeding wilt-resistant varieties of cotton is complicated by the search for new methods and donors of resistance to the pathogen. It is necessary to improve the method of selection of parent pairs during hybridization and qualitative assessment of interspecific hybrids at the early stages of the breeding process in order to increase the efficiency of breeding, speed up the process of introducing new varieties of cotton into production.The selection must be carried out on the basis of physiology and biochemistry of signs of resistance of the initial breeding material. The initial stage of selection should be based on test signs of resistance, which are associated with the catalytic activity of some enzymes involved in the formation of phytoimmunity against fungal infections (peroxidase, phenylalanine ammonialyase, polyphenol oxidase).The greatest interest of researchers is attracted by protective mechanisms, including the processes of lignification of cell walls and the biosynthesis of phenolic phytoalexins. These mechanisms simultaneously create a mechanical and chemical barrier to the penetration of fungal structures into the cell, preventing the spread of the pathogen.


Dr. Vijay B S Gaur; Dr. Bindu Singh Gaur; Dr. Nazeem I. Siddiqui

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 8, Pages 1162-1169

Body Mass Index (BMI) has been viewed as a highest quality level for characterizing overweight and weight. BMI is a pointer of as a rule adiposity while Waist Circumference (WC) and Waist-to-Hip Ratio (WHR) are markers for stomach adiposity. The members were age-, sex and weight-facilitated preceding being discretionarily consigned into 3 social occasions, with 18 members for each get-together. The lively strolling pack was expected to energetic walk multiple times every week at a force of 60-70% of their specific age-foreseen most outrageous heartbeat for around two months. 50 subjects mean (FSD) age 45.7 F 9.4 years were randomly apportioned to it is conceivable that one lively walk. Results showed that there was more essential improvement in cardio-respiratory preparation for lively strolling and opposition planning get-togethers (p<0.01) at present mediation took a gander at on pre-intercession regard. There were also critical enhancements in level of muscle versus fat, weight record (BMI), abdomen hip proportion (WHR), and free fat mass in the energetic strolling gathering. Moreover, members in the obstruction getting ready pack had critical improvement in BMI, WHR. Hence, it is assumed that both energetic strolling and opposition getting ready for around two months were proper exercise modalities to decrease a part of the cardiovascular danger factors among overweight and stout people.

Exploring The Salinity Tolerant Variety Of Rice

Mansoor A. Malik; Mehrajud Din Talie; Tajmul Islam; Juniad A. Magray; Purnima Shrivastava

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 2371-2382

Soil salinity affects several physiological and biochemical processes in plants. Plant culture of mixed composition and different concentrations of salt treatments were applied for 10 days to detect the response of the salinity tolerant variety of Rice regarding growth, survival, plant height, leaf area, leaf injury, relative growth rate. In vitro superoxide dismutase (SOD), ascorbate peroxidase (APX) and catalase (CAT) activities in the leaves are also screened. Most influenced genotype was IR-64 in terms of growth and dry matter and PB-1 for root length. Maximum SOD activity was recorded in PB-1 followed by IR-64. However, HKR-127 the minimum SOD activity was recorded. APX activity showed large variation in rice genotypes following Sodium chloride (NaCl) treatment. APX activity increased significantly in PB-1 over control in dose dependent manner in all the treated samples. The maximum (25.0%) APX activity was observed in PB-1 at T4 treatment over control. Salt treatment remarkably increased the APX activity in IR-64 up to T3 level of NaCl treatment. In HKR-127 genotype at all levels of treatments there was non-significant increase in its activity. Moreover, Catalase activity in PB-1 increased significantly with all the treatments. The difference among treatments was significant at all levels the highest activity (26.3%) was at T4 level of treatment in PB-1 genotype. IR-64 genotype showed increased catalase activity up to T3 level while in HKR-127 increased non-significantly in CAT at all treatments. The data are discussed in regard to implications of salt stress.


Khaldarbekova G. Z.; Muhamedov I. M.; Tarinova M. V.; Shigakova L. A.

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 3183-3191

Scientists have been researching for a long time, where they have found evidence of a connection between “Lactobacillus - Caries”. According to the results of some countries, the qualitative and quantitative composition of lactoflora of the oral cavity is already known in the norm and case of diseases caused by disbiotic conditions of the mouth. This article presents the results of the quantitative and qualitative composition of oral lactoflora of women of fertile age, the state of biological properties of each particular representative and their impact on cavities formation, which can explain the microbiological etiology of cavities. Each of the following indicators was statistically processed and compared with the results of foreign countries.

Influence Of Different Concentrations Of Dimethylsulfoxide Solution On Antibiotic Sensitivity Of Pathogenic Microorganisms In Experiment (In Vitro)

SafoyevBakhodir Barnoyevich; YarikulovShukhrat Shokirovich; BoltayevTimur Shavkatovich

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 5194-5198

The fight against surgical infections remains an urgent problem in surgery. The problem of microflora resistance makes it difficult to obtain positive results of purulent-surgical diseases of soft tissues. In the literature, there are few studies devoted to the suppression of the existing microflora resistance to antibiotics.
The aim of the study: There was a laboratory study of the microbiological activity of dimethylsulfoxide, the identification of the optimal concentration of the solution with the maximum bactericidal and suppressive properties of the resistance of pathogenic microflora in vitro.
The results of the experimental in vitro studies have shown that 25% dimethylsulfoxide is the optimal concentration in terms of suppressing microflora resistance.