Keywords : ACE expression
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 1, Pages 186-193
The present review provides valuable information about the ACE expression and its association with hypertension in COVID-19 patients. The potent use of angiotensin converting enzyme inhibitors, found to increase the ACE expression in hypertension and cardiovascular diseased patients which leads to acute lung injury. Currently there is no clear evidence that impact use of ACEI or ARBs could increase the severity of COVID -19 infection in hypertensive patients.COVID -19 being an infectious disease increases the mortality and morbidity of patients with hypertension. Previous studies have been reported that hypertension is considered as a prognostic indicator in SARS nCov infection. Few studies have also reported that there is no significant association of ACE expression with Covid 19. Review data was collected using the recent articles searched from PubMed, the google scholar, core, Cochrane, from 2000 to 2020. The present review highlights all the possible factors between ACE expression among hypertension patients and covid disease.