Online ISSN: 2515-8260

Keywords : Natural medicine


ROLE OF DIETARY POLYPHENOLS IN THE MANAGEMENT OF PEPTIC ULCER

Barani Shankar; Jayalakshmi Somasundaram; Lakshminarayanan Arivarasu

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 1541-1546

Peptic ulcer disease is a multifactorial and complex disease involving gastric and duodenal ulcers. Despite medical advances, the management of peptic ulcer and its complications remains a challenge. An accumulating body of evidence suggests that, among a broad reach of natural molecules, dietary polyphenols with multiple biological mechanisms of action play a pivotal part in the management of gastric and duodenal ulcers. The current review confirmed that dietary polyphenols possess protective and therapeutic potential in peptic ulcer mediated by: improving cytoprotection, re-epithelialization, neovascularization, and angiogenesis; up-regulating tissue growth factors and prostaglandins; down-regulating anti-angiogenic factors; enhancing endothelial nitric oxide synthase-derived NO; suppressing oxidative mucosal damage; amplifying antioxidant performance, antacid, and anti-secretory activity; increasing endogenous mucosal defensive agents; and blocking helicobacter pylori colonization associated gastric morphological changes and gastroduodenal inflammation and ulceration. In addition, anti-inflammatory activity due to down-regulation of proinflammatory cytokines and cellular and intercellular adhesion agents, suppressing leukocyte-endothelium interaction, inhibiting nuclear signaling pathways of inflammatory process, and modulating intracellular transduction and transcription pathways have key roles in the anti-ulcer action of dietary polyphenols.Polyphenols ubiquitously present in vegetables and fruits are progressively viewed as natural dietary ingredients vital for a balanced diet. Administration of a sufficient amount of dietary polyphenols in the human diet can result in perfect prevention and treatment of peptic ulcer. In conclusion, administration of a significant amount of dietary polyphenols in the human diet or as part of dietary supplementation along with conventional treatment can result in perfect security and treatment of peptic ulcer. Further well-designed preclinical and clinical tests are recommended in order to recognize higher levels of evidence for the confirmation of bioefficacy and safety of dietary polyphenols in the management of peptic ulcer

AWARENESS ON THE BENEFICIAL EFFECTS OF NATURAL MEDICINE AMONG ADULTS

Shreejha M. V; Kavitha. S; Vishnu Priya. V; Gayathri. R

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 311-323

Introduction: There has been a global rise in the use of natural products and natural medicine among
people. Proper regulation of natural medicine and products ensure good quality to control standards,
enhance the consumers safety that facilitate their modern healthcare system, mainly because of their lack
of side effects.
Aim: The aim of the study is to determine the knowledge, awareness and attitude, towards natural
medicine and products among adults.
Materials and methods :A cross sectional study was conducted among the adults [101people]. The
questionnaire was circulated online through google forms and the collected data were analysed using SPSS
software. The Pearson Chi square test was done in association with the gender of the respondents.
Results: The survey results showed that 79.2% of the people have knowledge about natural medicine.
90.1% of the participants believe natural medicines are effective, 75% of the participants use natural
medicine products in their regular life, 61.4% said natural medicine is more effective than pills.
Conclusion: The present study showed that the awareness and knowledge on natural medicine among
adults is quite good.