Online ISSN: 2515-8260

Keywords : Risk factor

A Study to assess the prevalence of Head and neck squamous cell carcinomas in association with tobacco consumption in a tertiary care hospital

Dr. Durgadevi; Dr. Jayaganesh

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 879-885

Head and neck cancers are the sixth most common type of cancers and has a steady rise in
India, predominantly in males .The most common etiological factor contributing for the
cancer development is Tobacco consumption in various forms. This was a laboratory based
,retrospective study to assess the prevalence and association of HNSCC in a subset of
population of tobacco consumers A total of 50 positive cases of Head and neck squamous
cell carcinomas were collected at our hospital for a period of two years and history collected
in view of age , sex and tobacco consumption . In this study, 64% affected cases are males
and 48% of the cases had the history of tobacco consumption. Tobacco consumption prevails
as the sole risk factor for the development of Head and neck squamous cell carcinomas

Prevention of complicationsand several other relevant risk factors of Type 2 Diabetes(T2D)at a hospital in Vietnam

N. V. Chinh; P. H. T. Kiet; P. B. Diep; N. T. B. Yen; Dong Wang; L. D. P. Cuong; P. D. Trung; L. M. N. Uyen; N. H. Tu

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 10, Pages 266-279

Diabetes has a significant incidence of illness, health care effects and lead to a high mortality rate due to its complications in both developed and developing countries so far. Diabetes can be divided into three main types: Type 1 diabetes, Type 2 diabetes and Gestational diabetes, the most common type is Type 2 diabetes (T2D). Our work focuses on researching the relationship of complications and their cost of treatment in order to make the treatment plan and minimize its costs in at the Thanh Nhan hospital in Hanoi, Vietnam. Therefore, the research results show that there are many different types and rates of complications of T2D depending on key factors such as: age and duration of the disease, by determining the complication rate and analyzing multivariate logistic regression models to find the risk factors associated with an increase in the number of complications of the disease from the Social Science Package Statistics (SPSS) software and other.


Yakutkhon Madjidova; Durdona Mukhammadzhanova; Nodira Azimova; Gulchekhra Isakova; Aziza Dzhurabekova; Shavkat Kabilov

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 3112-3117

The article presents the results of a study of 52 children with various forms
of cerebral palsy. The analysis of risk factors for the development of cerebral palsy. The
diagnosis of cognitive impairment, including memory impairment in children with cerebral
palsy, is one of most significant tasks, since it determines the characteristics and prognosis of
both medical and social rehabilitation, while the differentiation of retardation of mental
retardation and marked retardation is extremely significant.

Analysis Of Risk Factors For Pulmonary Tuberculosis Incidence In Type-2 Diabetes Mellitus Patients

Hari Setiawan; Harun Iskandar; Himawan Sanusi; Syakib Bakri; Makbul Aman; Hasyim Kasim; Haerani Rasyid; Nur Ahmad Tabri; Arifin Seweng

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 1495-1499

Background:Incidence of pulmonary TB in type-2 diabetes mellitus patients is still high. Gender, age, nutritional status, duration of diabetes, blood glucose control, smoking habit, and HbA1c, are among risk factors that influence its occurrence. This study aims to analyze the risk factors that contribute to the incidence of pulmonary TB in type-2 DM patients in Makassar.
Methods:A survey analysis study at Wahidin Sudirohusodo Hospital. Hasanuddin University Hospital. and educational network hospital.on December 2019 until the desired sample reached. Sample collection using consecutive sampling. Data analysis using SPSS verse 22. Statistical analysis using pearson’s correlation. chi square test. and multiple logistic regression (backward method). Significant result if p value <0.05.
Results:Study included 225 type-2 DM patients. From study shows distribution of pulmonary TB in type-2 DM patients is 13.3%. Incidence of pulmonary TB was high in patient with underweight (OR=6.7 and p<0.05), duration of DM>5 years (OR=3.8 and p<0.05), and uncontrolled blood glucose (OR=2.7 and p<0.05). There was no significant correlation between gender (female 19 from 135, male 11 from 90 with p>0.05), age (age >60yo 15 from 92, age ≤60yo 15 from 133 with p>0.05), smoking habit (yes 10 from 84, no 20 from 141 with p>0.05) and HbA1c (A1c <7 was 0 from 7 and A1c ≥7 was 30 from 165 with p>0.05) with pulmonary TB incidence.
Discussions:Incidence pulmonary TB in type-2 DM patients according to BMI was significant (p<0.05) because condition of malnutrition can lowering the immune status by decreased the limphocytes production and immune proliferation also decreased of IFN-gamma and IL-2 level, and increased of TGF-beta. Incidence according to duration of DM was significant (p<0.05). Incidence according to blood glucose control was significant (p<0.05), DM and uncontrolled blood glucose can lead to an immune compromise condition, some of risk factors that also can contribute to infection disease.
Conclusion:There was significant correlation between underweight, duration of DM >5 years, and uncontrolled blood glucose with pulmonary TB incidence.

C-reactive protein and periodontal disease – A Review

Mohana Kondapally; Ramesh KSV; NVS Sruthima; Gautami S Penmetsa; P. Mohan kumar; G. Meghana

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 1664-1670

C- reactive protein (CRP) is an acute phase protein observed in increased quantities in plasma during the infections and presence of any inflammation, which could be a further possible risk factor in systemic inflammatory diseases such as arthritis, diabetes mellitus, and obesity. CRP molecules help as a biological marker for the determination of the inflammatory process when obtained from the gingival crevicular fluid and there is association between periodontitis and CRP levels. These levels are found to be reduced after the non-surgical and surgical periodontal treatment. Therefore, the levels of CRP would play a major role in determination of the inflammatory process.

Obesity As A Major Risk Factor In N- Cov Disease.

J. Dhivyadharshini; A.S.Smiline Girija; Jayalakshmi Somasundaram

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 2562-2571

The review gives an overview on the relation between obesity and n-CoV disease. A review has been done to understand the correlation of obesity with the n-CoV disease by retrieving a maximum of related articles from various search engines like PubMed, Google Scholar, MeSH, Core, Cochrane, bioRxiv, Semantic scholar and so on published from 2000 to 2020 (till date). Obesity is associated with SARS- CoV-2 which enhances inflammatory response in obese people compared to actual standard BMIs. Obesity is often specifically related to producing inflammation by triggering a cytokine storm in the lungs, which raises the likelihood of ARDS, thereby requiring respiratory assistance for the main issue. Obesity can hinder breathing by hampering the excursion of the diaphragm, inhibit immune responses to critical infection, it is pro-inflammatory and triggers diabetes and even oxidizing tension to worsen cardiovascular activity. This study indicates that obese people through respiratory viruses COVID19 are more likely to be hospitalized comparatively. The implementation of novel ideas on obesity control of ailments will certainly bring about a massive change. Constraining less dependence on recent literature in this area and also upgrading numerous research to increase consciousness among the general public so that they may take measures not to be vulnerable to COVID 19. The current research has shown a strong incidence of obesity in patients participating in medical treatment with SARS-CoV-2. Obesity can be hazard factored to SARS-CoV-2 severity which needs increased attention in susceptible individuals to take preventive measures