Online ISSN: 2515-8260

Keywords : pediatrics


Mousa Mohamed Dabboub,Abdallah Attia Mohammad, Ashraf Abd El Dayem Mohammad,Hossam Fathi Mahmoud

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 4645-4652

Background: A sufficient background and careful initial clinical evaluation are needed for the assessment and treatment of the supracondylar fracture of the humerus. The study aimed to evaluate the results of cross lateral ascending and descending pinning in pediatric supracondylar fractures humerus. Patients and methods: This study included 18 children with supracondylar humerous fractures who underwent lateral pinning in the pediatric department, the hospitals of Zagazig University, and the hospital of teaching Ibnsina. Surgical technique was performed and outcomes were recorded. Results: Regarding cosmetic score, more than half of the studied group (55.6%) had excellent, (27.7%) of them had good and (11.1%) had fair and (5.6%) had poor cosmetic score respectively. Concerning Flynn's Score, more than half of the studied group (55.6%) had excellent functional outcome, (27.7%) of them had good functional outcome and (11.1%& 5.6%) had fair and poor functional outcome respectively.There was statistically significant difference between patients with satisfactory and unsatisfactory outcome regarding presence of complications and mechanism of injury with better outcome in injury due to FD and patients with satisfactory outcomehad no complications. Conclusion: Near manipulation and percutaneous attachment in the paediatric age group is an appropriate and conclusive treatment procedure with two crossing-lateral K wire of Gartland type II and III supracondylar fractures with less complications.

Complex Approach To The Diagnosis Of Cystic Fibrosis In Children

Shohsanam Bahromovna Uzakova; Furkat Mukhitdinovach Shamsiev; Nargis Khayrullaevna Mirsalikhova; Nigora Davlyatovna Azizova; Rano Anvarbekovna Musajanova; Nilufar Irgashevna Karimova

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 3003-3007

The aim of the study was to study the clinical and diagnostic features of cystic fibrosis in children in Uzbekistan. The study included 120 patients with cystic fibrosis at the age of 0 months. up to 14 years old, who were inpatient treatment in the department of pulmonology, pathology of early age and gastroenterology. In children with cystic fibrosis, the main clinical symptoms of the bronchopulmonary system were: cough, shortness of breath, oral wheezing, lethargy and loss of appetite. Upon admission to the hospital, the general condition of the patients was most of all regarded as severe. The most common causative agents of the disease exacerbation were S. aureus - 32%, Str. pyogenus - 26%. Based on the results of the study, the frequency of mutations in the CFTR gene and their influence on the nature of the course were determined. A significant role has been revealed for the 4 most common gene mutations in Uzbekistan, CFTR-F508del, CFTR-2143delT, R709X, Y569D.

Modern Approaches To The Selection Of Protected Cephalosporins Iii For Therapy Of Community-Acquired Pneumonia In Children

Mukhlisakhon Ravshanhanovna Kurbanova; Furkat Mukhitdinovach Shamsiev; Rano Anvarbekovna Musajavova

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 3008-3014

The aim of the study was to study the effectiveness of the use of protected cephalosporin III generation Extum in the treatment of community-acquired pneumonia in children. The study included 100 children with community-acquired pneumonia at the age from 1 to 15 years, who were observed and treated in the department of pulmonology. In the process of complex clinical and laboratory examination of children, biochemical, microbiological and immunological research methods were used. Microbiological studies have shown that in children with community-acquired pneumonia, S. Pneumonia occupies a significant place in the etiological structure and accounts for 42.0% of cases, a high sensitivity of pneumococcus to injectable cephalosporin of the third generation has been established. When included in complex treatment, protected cephalosporin of the third generation Extum leads to a decrease in the frequency of repeated acute respiratory infections and their complications by 2.2 times, the frequency of recurrent bronchitis and pneumonia by 1.7 times, which indicates a high therapeutic effectiveness of the proposed treatment


K. Sree Kala Priyadharsini; Lakshminarayanan Arivarasu

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 376-382

Accurate localization of the seizure onset zone is important for better seizure outcomes and preventing
deficits following epilepsy surgery. Recent advances in neuroimaging techniques have increased our
understanding of the underlying etiology and improved our ability to noninvasively identify the seizure
onset zone. Using epilepsy-specific magnetic resonance imaging (MRI) protocols, structural MRI allows
better detection of the seizure onset zone, particularly when it is interpreted by experienced
neuroradiologists. Ultra-high-field imaging and postprocessing analysis with automated machine learning
algorithms can detect subtle structural abnormalities in MRI-negative patients. Tractography derived from
diffusion tensor imaging can delineate white matter connections associated with epilepsy or eloquent
function, thus, preventing deficits after epilepsy surgery. Arterial spin-labeling perfusion MRI,
simultaneous electroencephalography (EEG)-functional MRI (fMRI), and magnetoencephalography
(MEG) are noninvasive imaging modalities that can be used to localize the epileptogenic foci and assist in
planning epilepsy surgery with positron emission tomography, ictal single-photon emission computed
tomography, and intracranial EEG monitoring. These advanced structural and functional imaging
modalities can be combined with postprocessing methods to better understand the epileptic network and
obtain valuable clinical information for predicting long-term outcomes in pediatric epilepsy.