European Journal of Molecular & Clinical Medicine

Asthma is the most prevalent non-transmissible disease that entirely affects quality of life. Management of such diseases is a pre-requisite. . Modern biological therapy for extreme asthma care, along with biomarker advances, provide the potential for phenotypic-specific therapies and introduction of more tailored procedures. Although many measures were adopted to overcome from this issue but still some side effects are faced while using synthetic medications. The present review discusses about herbal medication that were adopted by different countries to cure asthma. Discussion of Chinese, Japanese, Indian and alike herbs were done along with their clinical trials conducted on different subjects. Final a conclusion is drawn wherein it is observed that herbal medications were effective in treating asthma but a full reliance over them may sometime cause serious consequences as it not always herbs are found to be effective on different subjects. The reason may be due to mis-guiding during preparation of the formulation or incorrect labelling of the formulation

With the raising concerns on the mortality rate in the recent covid pandemic, the lacunae of proper treatment strategy plays a vital factor. Since there is no approved medication for COVID-19, medications involving hydroxychloroquine sulfate and chloroquine phosphate were recently recommended. The National Medical Products Administration of China has approved Favilavir, an antiviral medication, with minimal side effects and a moderate control on viral replication. Remdesvir, another antiviral, has drawn the attention of several researchers to treat the novel COVID-19 virus as COVID-19 is identical to SARS and MERS viruses. Remdesvir, was successful in the previous outbreaks of SARS and MERS. Some researchers also suggest high doses of vitamin C supplementation may improve the patient''s condition. This review thus provides a basic overview on the recommended medication and urges the need to develop novel anti-covid drugs and vaccines.

Introduction: Lichen planus, is a chronic autoimmune, mucocutaneous disease affecting the oral mucosa besides the skin, genital mucosa, scalp and nails.The exact etiology of oral lichen planus is unknown. The disease most commonly affects middle-aged females. Oral lichen planus usually presents as white striations (Wickham's striae), white papules, white plaque, atrophic , ulcerative, erosive or as blisters. There is a well established correlation between oral lichen planus and liver disease. Opinion amongst researchers vary on terminology of lichen planus and lichenoid drug reaction . Recent literature reported association between lichen planus and thyroid disease.
Aim: The main aim of this study is to evaluate the association between oral lichen planus and thyroid disease and its prevalence amongst patients visiting our dental institute.
Materials and methods: 67 case sheets of patients, diagnosed with oral lichen planus between June 2019 and March-2020 were retrieved from the electronic database . Collected data were entered into the Excel sheet and was analysed using SPSS analysis.
Results: Results showed a positive association between oral lichen planus and thyroid disease, mainly hypothyroidism (7.46%). Females were more affected than males (53.7%).The erosive variant of oral lichen planus was more prevalent among the study population (44.7%). There was a positive correlation between predominant clinical variety of Lichen planus and site involved. The positive correlation between hypothroid state and lichen planus is also reported.
Conclusion: In conclusion, our study establishes an association between oral lichen planus and a coexisting thyroid disorder mainly hypothyroidism .