Online ISSN: 2515-8260

Keywords : Healing


Baykulov Azim; Abdullayev Davlat; Narzikulov Rustam; Oripov Rustam; Yermanov Rustam; Mamirov Vasliddin; Islamov Nurali

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 1785-1808

Background: Despite the vast experience of treating burns in surgery, a large number of victims become disabled; therefore they represent a serious medical and social problem.
Methods: The study included 120 white outbred male rats, which were simulated an experimental 3-degree topical burn and were divided into 4 groups according to the type of treatment substance. The burn was simulated by immersing the depilated skin area in boiling water. Studies of wound healing were carried out in three series, respectively, on the third, seventh and tenth days.
Results: We found that the local application of chitosan derivatives at an early stage leads to healing of the wound defect in rats in our experimental model. This was associated with a decrease in endogenous intoxication, lipoperoxidation, and internucleosomal degradation compared to the control group.
Conclusion: Thermal damage is accompanied by increased internucleosomal skin degradation. Compared with levomecol, chitosan derivatives more effectively reduce the degree of internucleosomal degradation, especially on the 10th day of the experiment.

Non-Surgical Endodontic Approach for Management of Periapical Lesions with 6 months follow up: A Case Series.

B. Sravan Kumar; M.S. Rangareddy; Basa Srinivas Karteek; Chavva Lakshmi Charan Reddy; Md Abdul Wahed

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 2, Pages 1524-1531

The success of root canal treatment depends on thorough disinfection of the root canal system, and to provide fluid impervious seal which in turn halt the progress of the periapical infection. The oral microorganisms from the degenerated pulp tissue are responsible directly or indirectly for most of the periapical lesions. For the treatment of these lesions there are surgical and non-surgical methods. Surgical removal of the periapical lesion without proper root canal disinfection and obturation will result in improper healing of lesions whereas in non-surgical root canal therapy the lesions heal if proper cleaning, shaping and obturation of root canal are done. This clinical case series highlights the follow-up results of three cases demonstrating the resolution of periapical lesion through nonsurgical approach and confirms that periapical lesions respond favorably to non-surgical treatment

Assessment Of Outcome Profile Of Patients With Peri-Apical Surgery- An Observational Study

Dr. Tejveer Singh; Dr. Naresh Kumar; Dr. Rupinder Bansal; Dr. Gursandeep; Dr. Mehak Goyal; Dr. Himanshu Sood

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 8, Pages 3673-3677

Background: The present study was conducted to assess profile of patients undergoing apical surgery.Materials & Methods: 56 patients were selected for peri- apical surgery of both genders. Follow-up was done at 1, 3, 6, and 12 months and every 6 months thereafter. Clinical and radiographic examinations were performed at each recall.
Results: Teeth involved was maxillary incisor in 12, maxillary cuspids in 20, mandibular incisors in 10 and mandibular cuspids in 14 cases. Prostheses were present in 25 and absent in 31 cases. Bony destruction pattern was apical in 45 and apico-marginal in 13 cases. Post was present in 14 and absent in 42 cases. The maximum healing was seen in maxillary incisor in 67% followed by maxillary cuspids in 52%, mandibular incisors in 65% and mandibular cuspids in 54%, 56% in teeth with prostheses, 82% in apical bone destruction and 76% in teeth with post. The difference was significant (P< 0.05).
Conclusion: There was better healing in maxillary incisors, teeth with prostheses present, teeth with apical bone destruction and teeth with post.

Comparative evaluation of healing after periodontal flap surgery using isoamyl 2- cyanoacrylate (bioadhesive material) and silk sutures: A Study Protocol

Dr. Diksha Agrawal; Dr. Priyanka Jaiswal; Dr. Deepika Masurkar

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2044-2051

Abstract: Background- The main goal in periodontal surgery is the healing by primary
intention because there is less scarring, more rapid healing and reduced discomfort.
Cyanoacrylate is a tissue adhesive which provides benefits to the patient as a faster healing
and less postoperative pain. Flap surgery for periodontal reattachment, demands close
postoperative adaptation for the gingival tissue onto the prepared tooth surface. Objective- To
evaluate the healing after periodontal flap surgery using isoamyl 2‑ cyanoacrylate and silk
sutures. Material and Methods- In this study, 40 patients of systemically healthy will be
selected. Groups will be divided into test and control which consist of 20 defects in each.
Informed written consent will be obtained from all the subjects before the surgery. Clinical
measurements like Plaque index, Papillary bleeding index, Probing pocket depth, Healing
index will be recorded. The test group will be treated by isoamyl 2‑ cyanoacrylate, while the
control group will be treated by Silk suture after periodontal flap surgery. Patients will be
recalled at 1, 3, 6 months post surgically for periodontal re-evaluation. Expected Result- When
all the parameters will be compared at 6 months post-operatively to baseline data, both the
treatment group (test and control) will show significant CAL gain, PPD reduction. Test group
will be found better healing as compared to control. Conclusion- Both the treatment group
(test and control) will show significant CAL gain, PPD reduction. This study will be achieved
effective healing response after periodontal flap surgery with sutures as compared to


Prabhav Kumar Iyer; Dr. Deepika Rajendaran; Dr. Sarvana Dinesh S.P

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 660-676

Hyperglycemia is a condition in which there is an increase in the blood glucose level of the person. It is one of the most common systemic conditions in middle aged Indians. It is important for a dentist and dental students to be aware of the condition especially while performing invasive procedures as delayed wound healing, coma and hypoglycemic shock are some of the most common complications encountered in some patients. Hence, it is important to know about this condition to prevent any kind of medical emergency on a dental chair. The aim of the study was to assess the knowledge and attitude of dental students while managing hyperglycemic patients indicated for extraction. This study was carried out in a self administered questionnaire format among the students of a dental university. The questionnaire was created on an online platform called “Survey Planet” and was filled by 100 students. The questionnaire consisted of the major aspects of knowledge on hyperglycemia and how students will manage the patient before performing the extraction procedure on them. Based on the tabulated results, it was seen that dental students have greater knowledge towards dealing with hyperglycemic patients indicated for extraction. 64% said that they can perform extraction on a hyperglycemic patient. 93% said that they would test an elderly patient to check their blood glucose level before the procedure. 72% were aware of the management of hyperglycemia. 45% of the participants said that they would do the treatment only after the patient consulted a physician. 11% said that they would deny the treatment. 82% of the participants said that they would keep the appointment for the extraction in the morning. Thus we can conclude that dental students have good knowledge and attitude toward managing hyperglycemic patients indicated for extraction