Online ISSN: 2515-8260

Keywords : haemoglobin


A Case control study on the Association of Serum Ferritin levels with Acute Myocardial Infarction

Vadiga Ramana Kumar, Atul Pundlik Ramteke, Guguloth Prem Kumar

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 2647-2655

Background: To evaluate the serum ferritin levels in patients with acute myocardial infarction. To inspect normal healthy individuals with non-cardiac chest pain for serum ferritin levels. To distinguish ferritin levels persisting in both the study population. Comparing serum ferritin levels to the probability of developing acute myocardial infarction. To study relevance of serum ferritin level to acute myocardial infarction.
Material and Methods: A case controlled study was held by Department of General Medicine, Government General Hospital, Suryapet, Telangana, India from December 2021 to September 2022. The study consisted of male patients with myocardial infarction for determining the association of serum ferritin to acute myocardial infarction.
Results: The statistical analysis data for the evaluation of study details for different diagnostic test between cases and control group and determines significance between them. Comorbidities associated with cases and control shows that evidence of diabetes mellitus. The comparison of ferritin and lipid profile no significance existed. On differentiating ferritin administrated value to that of day 3 shows statistical significance. While comparing ferritin and glycaemic control, correlation prevailed. A mixed results were obtained from performed study that proved insufficient to correlated ferritin with myocardial infarction.
Conclusion: The study contradicted the hypothesis. Neither of the tested iron biomarkers confirmed the iron hypothesis, based on the meta-analysis. These finding suggest that the evidence is not robust enough to support the connection among iron and cardiovascular disease. This discrepancy in results could be due to the study's use of different iron markers. Despite the large amount of data that has been published to far, the importance of iron in CVD is still up for debate.

A CROSS-SECTIONAL STUDY OF ANEMIA IN THE THIRD TRIMESTEROF PREGNANT WOMEN IN GOVT GENERAL HOSPITAL & COLLEGE, NIZAMABAD

Dr. D. Anupama, Dr. G. Aparna, Dr. Saroja Adapa, Dr. B. V. Surendra .

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 465-471

Background: In pregnancy, anemia is a common disorder and is associatedwith an increased risk ofmaternal, fetal, and neonatalmorbidity and mortality. The present study was conducted to determine the prevalence and risk factors of anemia among III Trimester pregnant women attending OBG department, Government medical college &general hospital, Nizamabad.
Methods: A hospital based cross sectional study was conducted on 392 III Trimester pregnant women attending antenatal care at Governmentmedicalcollege&general hospital, Nizamabad from October 2020 to March 2021. Data on socio-demographic and clinical characteristics of the study participants were collected using a questionnaire and medical records. The haemoglobin was measured using an automated cell counter method and those with hemoglobin level less than 11 g/dl were considered as anaemic.
Results: The overall prevalence of anemiain our study was found to be 192 (48.9%).The age of the patients ranged from 18 to 35 years. out of all anaemic pregnant women about 100 were mildly anemic, 82 were moderate anaemic &10 were severe anaemic. Iron folic acid supplementation, antenatal care visit were significantly associated with the prevalence of anemia.
Conclusion: There is a high prevalence of anemiain III trimester pregnant woman attending tertiary care hospital in Nizamabad.Iron supplementation and health education to create awareness about the importance of antenatal care are recommended to reduce anemia.

A PROSPECTIVE STUDY OF AETIOLOGY AND OUTCOME OF ACUTE KIDNEY INJURY IN TYPE 2 DIABETES PATIENTS

Dr. Bibhuti Nath, Dr. Abdul Jabbar Ansari, Dr.U. K. Ojha

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 1278-1282

Introduction: Acute kidney injury (AKI) is a protean syndrome of varied severity. It is characterized by a rapid (hours to weeks) decline in the glomerular filtration rate (GFR) and retention of nitrogenous waste products such as blood urea nitrogen (BUN) and creatinine.1,2 The RIFLE criteria, proposed by the Acute Dialysis Quality Initiative (ADQI) group, aid in the staging of patients with AKI.
Materials and methods: A prospective study was conducted at the Shaheed Nirmal Mahato Medical College (SNMMCH), Dhanbad from January 2021 to December 2021 (1 year). Type  2 diabetic  patients  30  years  or  above,  irrespective  of gender, diagnosed to have acute kidney injury using KDIGO criteria, admitted to ICU or wards under the Shaheed Nirmal Mahato Medical College (SNMMCH), Dhanbad were included. Patients with preexisting renal disease and those who received renal transplantation. Type 2 diabetic patients  admitted  in  the  ICU  and wards under Shaheed Nirmal Mahato Medical College (SNMMCH), Dhanbad were evaluated  in  detail  after  taking  prior  consent. Evaluation includes detailed history taking and physical examination. Acute kidney injury will  be  assessed  on  the basis  of  their  serum  creatinine  and/or  urine output fulfilling the KDIGO criteria.
 
Results: The study  was  conducted  in  a  total  of  75  diabetic  patients who developed acute kidney injury. There were 47 males and 28 females. The aetiology and outcome of acute kidney injury in the above patients were found out. Blood urea, serum creatinine, serum electrolytes, fasting and post-prandial blood sugar, WBC count, platelet count and haemoglobin were included as the baseline parameters.
Conclusion: Infection  was  the  most  common  cause  of  AKI  in  Type  2diabetes patients  in  our  study. Among  drug  induced  renal  failure  patients, NSAIDS  were noted  to  be  most  common  cause. Age >60 and male gender were prevalent in the majority of AKI patients. About 52.66% of the total patients recovered to normal renal function, 13.3% recovered partially, with 14% of the total patients progressed for maintenance hemodialysis. Crude mortality rate among patients with AKI in the study group was 20%.

KNOWLEDGE, PREVALENCE AND RISK FACTORS OF ANAEMIA AMONG PREGNANT WOMEN

Sharwini Baskar; Karthik Ganesh Mohanraj; Preetha. S

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 748-763

Pregnancy has some physiological changes which complicate the process of diagnosis and treatment. Over 200 million people suffer from anaemia especially among women of reproductive age. Anaemia is a major health problem among pregnant and non-pregnant women. Anaemia during pregnancy is considered as a public health problem especially in developing countries. The World Health Organization (WHO) defined anaemia during pregnancy as a haemoglobin concentration of less than 11g/dl. In severe anaemia, the haemoglobin level is 6g/dl. Anaemia threatens both mother and foetus. The causes may be multifactorial, such as nutrient deficiency, parasitic infections or chronic infections. It may also be due to acute blood loss. It may also depend on geographical location and economic status. The effects of anaemia on mothers are tiredness, weakness, dizziness and affects the immune system. In children, it may cause preterm delivery, low birth weight. On both the mother and the fetus it can cause mortality and morbidity. Intake of balanced diet and awareness programmes on anaemia is a measure to prevent anaemia. This study is to evaluate the awareness and prevalence of anaemia among pregnant women. A cross-sectional survey was conducted containing a set of self-developed questionnaires. The data was collected and analysed using SPSS software. The results are analysed and tabulated. The result was gained as follows, 25% of the participated population‟s haemoglobin level is less than 11, 75.89% of the population participated are aware that anaemia can affect pregnant women, 66.07% of the population agree that haemoglobin level less than 11 can cause anaemia. From the study, it is obvious that there is an awareness between the effects of anaemia during pregnancy.

ASSOCIATION BETWEEN HAEMOGLOBIN LEVEL AND SEVERITY OF PERIODONTITIS - AN INSTITUTION BASED STUDY

Subasree .Soundarajan; Sankari Malaippan; Priyalochana Gajendran

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 1933-1942

The aim of the study was to investigate the association between haemoglobin level & severity of chronic periodontitis. This retrospective study was carried out by analysing the patient records from June 2019 to March 2020 at Saveetha Institute of Medical & Technical sciences (SIMATS).Two forty four patients were included in the study. Parameters assessed were a)Demographic details – Patient name, Patient identity number, Age & Sex; b)Periodontal parameters – Probing pocket depth (PDD), Loss of attachment (LOA), Bleeding on probing (BOP), Severity of Periodontitis (mild, moderate & severe);c) Blood parameters - Haemoglobin levels (g/dl). Data was analysed using SPSS version 23.0. Bivariate Pearson correlation of Haemoglobin with mean PPD, mean LOA & mean BOP score were calculated. Mean Hb was compared with severity of periodontitis using ANOVA. A total of 244 patients were included in the study. The mean age of the study sample was 40.42 (±11.38). Females constituted about 58.06%, whereas males constituted 41.4% of the study sample. Majority of the population had severe periodontitis (64.76%), followed by mild periodontitis (18.03%) & moderate periodontitis (17.21%). The mean haemoglobin level in severe periodontitis (13.35g/dl) is higher when compared to moderate and mild periodontitis (13.30g/dl & 13.18g/dl respectively). Mean PPD was 5.24 mm, mean LOA was 4.6 mm & mean BOP score was 0.98. Association between mean CAL and mean haemoglobin levels was positive and statistically significant with a p value of 0.012. Mean Hb level was not significantly different with varying severity of periodontitis