Online ISSN: 2515-8260

Keywords : SARS

Study Of Studies Related To Epidemiology Of COVID-19 And Public Health Risk Mitigation Strategies: A Review

Neha Thakur; Dr. Sakshi Sharma

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 4780-4796

The aim of this paper is to study some of widespread infectious epidemic diseases i.e. SARS, MERS and coronavirus which has been impacted global health and economy on vast scale. There are approximately 70,000 coronavirus cases from 2019 (COVID-19) are confirmed, of that over a pair of, 1000 patients are fatal and this disease turned out to be a serious threat to global health. The first approach of this paper is to have in-depth knowledge about the structure of coronavirus, its structural proteins i.e. S protein and their biological activities for the virus have been discussed. The second approach is to focus on different phases of epidemic and response interventions which are mandate to slow down the spread of any disease till its complete elimination this can help to accelerate further work on studies for managing future public health emergencies. Proper and cumulative planning at international/national/community levels and organized strategic preparation for prevention and control of such epidemic diseases is need of the prevailing global risk.

Coronavirus: A Review

Jaipreet .; Anu Bansal

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 5927-5935

Coronavirus is the emerging mutagenic pathogenic microorganism that is affecting the human beings in a larger extent. The name is given after its crown shaped like structure. In this review, structure and history of coronavirus is explained in detail. The history depicts the similarity and dissimilarity of novid coronavirus with preexisting SARS virus. Apart from that review also concludes about the mechanism of action of virus, how it spreads and transfer in human system. The symptoms and preventive measures are also discussed in the review.


Dr..Gomathi M; Dr.Jaikumar S

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 5619-5626

The causative agent of coronavirus disease (COVID-19) has omnipresent worldwide spread, infecting more than two million people and causing over 150,000 deaths worldwide, resulting in devastating global health emergencies. Extreme acute respiratory syndrome 2 (sarkozydia) Early in its global expansion, the COVI-19 pandemic was further fuelled by insufficient access to laboratory research. Real-time RT-PCR Diagnostic Panel was the first test obtained from the US Food and Drug Administration on February 4, 2020, by the Centers for Disease Control and Prevention (CDC) 2019–Novel Coronavirus (2019–nCoV)1–3. This test was therefore introduced by a significant number of public health and clinical labs in the USA. Many manufacturers of commercial instruments then obtained EUAs for molecular SARS-CoV-2 identification. However, producers also assign reagents. Many of the clinical laboratories have therefore used several platforms to satisfy research criteria.

Immune Modulating Mechanisms Implemented To Control N-Cov Disease

Tahreem Fathima; A.S.Smiline Girija; D. Ezhilarasan

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 2551-2561

The n-CoV is a recent pandemic globally raising serious concerns on its exorbitance in both infection, transmission and mortality rate. It is an infectious disease driven by uncontrolled immune mediated inflammatory disease resulting in cytokine storms and acute respiratory respiratory syndrome. The virus affects the respiratory system and other organ systems and lower respiratory tract. Its initial symptoms include dry cough, nausea, fever, sneezing. In the virus and host interactions, both humoral and cellular immune response seem to play a vital role. Innate immunity is the first line of defence against virus invasion. Adaptive immunity also plays an important part in viral clearance via activated cytotoxic T cells that destroy virus-infected cells and antibody-producing B cells that target virus-specific antigens. With no proper medication to control the covid disease, researchers have implemented various immune mediated mechanisms to curb the viral replication and further establishment of the disease. This review thus highlights on the various immune-modulating mechanism implemented against covid disease with its limitations and challenges.


Surya Sitara; Ganesh Lakshmanan; Gayatri Devi R

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 897-907

COVID-19 is a viral infection associated with pneumonia that originated from Wuhan city in December
2019. In the end of 2019, it began spreading in China. It can spread through air droplets and close
communication with those COVID-19 infected people. There were similar episodes of novel respiratory
viral infection like SARS, MERS etc in the past. The main aim of this study is to determine the
comparative impact of day to day life in SARS, MERS and COVID-19. An online survey with a self
structured questionnaire to analyse the comparative impact of SARS, MERS and COVID-19 pandemic
was carried out. The questionnaire was designed using the online survey platform google forms and the
link was circulated through social networks and with the collected responses a descriptive statistical
analysis was carried out using the “SPSS software 2.0”. It is evident that around 97.7% of participants are
aware about SARS and MERS and nearly 92.2% of participants were aware about the symptoms of SARS,
MERS and COVID-19. Majority of participants were aware of the economic impact, social distancing and
intensity of harm caused by the COVID-19 than other epidemics. SARS, MERS and COVID-19 are dead
full respiratory disorders. This study revealed that the majority of the population were aware about the
difference on impact of these respiratory diseases on day to day life and graded the COVID -19 has the
most impact comparatively.