Online ISSN: 2515-8260

Keywords : alcohol


Demographic profile of patients with acute pancreatitis presenting to department of surgery, jorhat medical college: A clinical study

Richard Barla, MJ Gohain, Nilutpal Bora, NN Ganguly, AC Baro

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 1998-2007


Background: Acute Pancreatitis is a major health problem with significant morbidity and mortality. There is large geographical variability in incidence, disease severity and outcome with data related to prevalence rate lacking in our region. Present study is aimed to observe its demographic variability around the Jorhat Medical College.
Methods: First consecutive 50 cases of acute pancreatitis presented in the Jorhat Medical College during the study period from June 2020 to May 2021 were included in the study; data collected, systematically analyzed and statistically reviewed.
Results: Of the 50 cases, 33 (60%) were male while 17 (34%) were female. The mean age of the study sample is 37.04±13.52 (SD) years, ranging from 15 – 75 years. Majority of the patients are between 15-35 years. In 50% cases, alcohol is the most common aetiology followed by gallstones (36%), idiopathic in 10% cases. Alcohol is the most common aetiology among male and 15-35 years age group while gallstone is most common cause in females and 35-55 years age group. Among 50 cases, 41 (82%) are mild acute pancreatitis and 9 (18%) have severe acute pancreatitis. Majority of severe acute pancreatitis cases are male and alcoholic. Of 50 cases, among Hindus (n= 47) ethnic Assamese are 54%, Tea tribe 20%, Mising 10%, UP 6%, Bengali 4%, while Muslim 4% and Christian 2%. Gallstone is most common cause among ethnic Assamese and alcohol is the common cause in Tea tribe and Mising. Geographical distributions of the cases are as follows: Jorhat district 50% (n=25), Golaghat 32% (n= 16), Majuli 14% (n= 7) and Sivasagar 4% (n=2).
Conclusion: Acute pancreatitis is more common among male than female. Assamese are the most commonly affected ethnic group, gallstone being the most common cause among them. Alcohol is the most common aetiology in Tea tribes and Mising community. Male and alcoholics are more prone to severe acute pancreatitis. The incidence of acute pancreatitis is more in younger population 15-35 years and alcohol is the most common cause in this age group. Most of the cases are from Jorhat district followed by Golaghat, Majuli and Sivasagar.

Correlation analysis of stress and substance abuse among medical students

Dr. Parul Sharma, Dr. Gaurav Passi

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 167-172

Background: Substance abuse is increasing in young population of India at alarming rates. Younger
generation abuse the substance to gain temporary pleasure, to relive stress and under peer pressure.
Medical students are more prone to substance abuse because of longer working hours, high pressure
working environment and stress.
Objectives: Present study aims towards finding a correlation between stress and addictive behaviors, so
as to recognize the extent to which stress affects the medical students. Present study also focusses on
establishing comprehensive measures to manage stress among medical students.
Methodology: Total 200 undergraduate medical students were recruited in present study. The stress level
was analysed using perceived stress scale (PSS) and perceived academic stress scale (PASS). Substance
abuse was analysed using drug abuse screening test (DAST-10) and alcohol use disorders identification
test (AUDIT).
Results: A significantly high correlation was found in the stress level and substance abuse among
undergraduate medical students. PSS exhibit correlation of 0.3589 with AUDIT and 0.3194 with DAST.
PASS exhibit correlation of 0.4760with AUDIT and 0.3775with DAST.
Conclusion: Stress was found to be a significant problem among medical students and this leads to
consumption of alcohol and other illicit mind-altering psychoactive substances in an attempt to cope with
various academic and other life stressors.Awareness creation about the adverse effects of substance use
and academic counseling in the first 2-3 years of course and putative stress reduction interventions are
recommended and needed.

Clinical profile and evaluation of level of dependence of alcohol in patients of alcoholic liver disease

Dr. Mridul Arora, Dr. Aarish Bali, Dr. Karanpartap Singh, Dr. Kiran Kumar Singal, Dr. S.S. Kaushal, Dr. Shrdha Sharma

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 204-208

Introduction: In India, there is a high frequency of ALD, with alcohol being responsible for roughly
half of all instances of cirrhosis. However, not everyone who consumes alcohol develops the condition,
and the total chance of acquiring the disease in a person is determined by a number of variables. The
length, amount, and kind of alcohol ingested, as well as nutritional state, comorbid illnesses, sex, race,
and hereditary variables, may all have a role. Multiple investigations on the impact of drinking patterns
in the development of illness have shown conflicting conclusions.
Objectives: Present study aims towards analysing the clinical profile of patients with alcoholic liver
disease. Present study also aims to perform psychiatric screening using CAGE criteria and alcohol use
disorder identification test (AUDIT) scale for assessing the severity of alcohol dependence.
Methods: Present study was a single centric, prospective, observational and hospital-based study. 50
patients with clinical/investigational evidence of alcoholic liver disease were include in study. CAGE
Criteria to screen and alcohol use disorder identification test (AUDIT) scale was used for assessing the
severity of alcohol dependence.
Results: The mean age of the recruited patients was 50.80 ± 12.74 years. Among total 50 patients, 96%
patients were males and 4% of patients were females. Total 26% patients have CAGE score of four, 34%
patients have CAGE score of three, 40% patients have CAGE score of two whereas no patient had a
CAGE score of zero. AUDIT scoring indicate that 96% patients exhibit alcohol dependence, 4% patients
presented with harmful or hazardous drinking levels whereas no patient presented with Low-risk
consumption. A total of 96% patients were alive whereas mortality occurs in 4% patients in present study.
Conclusion: Our findings show a link between the type, amount, and duration of alcohol consumption
and the development of alcoholic liver disease.

To study psychiatric comorbidities, quality of life in patients with alcohol dependence and caregiver burden among the family members

Dr Manjit Singh, Dr Neeru Bala, Dr Sumanjeet Kaur, Dr Gurinderbir Singh, Dr PD Garg, Dr Rajiv Arora

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 5701-5711

Background: Alcoholism is a severe hazard to both individuals and society, and the
family bears the brunt of the disease's burden.
Aims and objectives:
1. To study the sociodemographic profile of patient of alcohol dependence.
2. To study the psychiatric comorbidity in patients with alcohol dependence.
3. To study the quality of life in patients of alcohol dependence.
4. To study the caregiver’s burden in family members of alcohol dependence.
Material and methods: The present study was conducted at Swami Vivekananda Drug
De-addiction and Treatment Centre under Department of Psychiatry, Government
Medical College, Amritsar with the primary purpose of determining the Psychiatric
comorbidities, Quality of life in patients of Alcohol Dependence and Caregiver burden
among their family members. For this purpose, minimum 100 patients of alcohol
dependence syndrome who were admitted in Swami Vivekananda Drug De-addiction
and Treatment Centre and their respective key caregivers during a period of 1 year
from 2020 to 2021 will be selected and studied. The nature and purpose of the study was
explained to the patients and their respective caregivers and an informed consent was
taken from each of them. After Certain set of questions were asked from annexures and
accompanying clinical assessment was done. Enrolled patients and their caregivers were
assured of confidentiality of the information given by them and data assimilated was
analyzed using standard methods.

An Exploratory Study To Assess Global Positive Transformation Of Alcohol Intake Among Medical Students At Selected Medical Colleges Of Pune City

Suresh K Sharma; DR. Tapti Bhattacharjee

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 2, Pages 1033-1040

BACKGROUND OF THE STUDY: Alcohol is the number one toxic substance consumed by people of all age groups, which makes its use a public health problem. The overall trend shows that university students are those who suffer the most pressure. Aims-The aim was to find out perception of alcohol intake regarding global positive transformation among medical students. Objective - assess the perception of alcohol intake regarding global positive transformation among medical students. To explore the alcohol related habits among medical students. Materials and Method-A work site cross-sectional descriptive study was conducted amongst 300 medical students at selected medical colleges of Pune City.Data was collected by screening questionnaire related to alcoholIntake. Result:In this study demographical data showed that majority of the student 152(50.6) from the age group of 18-21 years. Majority of students 208(69.33) are male.Related to the screening questionnaire of alcohol Intake among medical Students data showed majority of the students 185(61.66%) students’ parents does not drink alcohol, 185(61.66%) students doesn’t drink alcohol, 253(84.33%) students friend’s drink alcohol, 185(61.66%) of students not applicable for 1st Drink, for the circumstances of drunk alcohol or May drunk alcohol 115(38.33%) of students said for Enjoy Partying, For the spending on alcohol per month in that 185(61.66%) Not applicable, 185(61.66%) are not applicable for control their interest on drinking alcohol and 185(61.66%) says never drink alcohol.In that majority 52.86% medical students are showing Alcohol is a powerful agent that makes global positive transformation. Mean responses are 158.6 for true and 141.4% are for false responses. Which interpret that alcohol drinking make you positive at global transformation.
Conclusion: The present study conclude that medical students are showing Alcohol is a powerful agent that makes global positive transformation.

EFFECT OF SUBSTANANCE ABUSE ON PHYSICAL HEALTH OF ADOLESCENTS

KM Ashifa

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 3155-3160

Alcoholism is a detrimental and dangerous human act. Particularly it remains very
alive among teenagers. Adolescent is a period where young people grow from an infant to a
mature infant.(Sturmhöfel & Swartzwelder, 2004).Alcohol is the world third largest risk aspect
for illness and contributes to 4% of the worldwidetrouble of sickness(Rehm, 2011). It is
reasonably true that 2,5 million deaths are caused per year from alcohol with 9 percent of
deaths in the age group between 15 and 29 because of alcohol consumption (WHO, 2018).
Alcohol causes bereavement and disability. Consuming alcohol gives a danger of developing
physical health problems among adolescent. The physical problems like cancers, cardiovascular
diseases, eye irritation, body pain, severe head ache, hand shivering, sleeplessness and nervous
system damage. The present study tried to investigate physical hazards of adolescents due to
alcohol consumptions

Date Rape Drugs in Sexual Assaults: A Threat to Indian Society

Gaurav Singh; Pratik Singh; Piyush Jyoti

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 4677-4683

The increasing cases of sexual assaults and rape worldwide have made it very challenging for the various nations to deal with it. We are witnessing a huge technological advancement all over the seas. But so far, we have not been able to find any proper solution to deal with these types of crimes. If we talk about India, one of the fastest growing crimes are rape and sexual crimes of women and children. Rape is prevalent in both rural as well as urban areas, and now the cases of sexual assaults are being increasing in the group of high class and literate people.
One of the major reasons for that is the increasing drug and alcohol abuse, which have a direct relation with increasing cases of sexual assault cases in the nation. About 70% of the sexual assault cases in India are reported which is committed while the Accused, victim or both are under the intoxication of some kind of drug or alcohol. The use of one such drug called the ‘Date Rape Drugs’ is becoming very prevalent in India. These drugs are used for exploiting the victim for the drug facilitated sexual intercourse. The reason why these drugs are becoming very popular among such abusers is that, these drugs produces effects which makes the victim physically helpless by reducing their physical strength so that they become unable to refuse the situation. Also, one more reason is that, this drug also affects the mental capability of the victim, thus the victim can’t remember and recall the situation. It is very easy for the perpetrators to mix these drugs in food and drinks of the possible victims because these drugs don’t have any smell, taste or any color. Thus, the date rape drugs are the perfect tool for such perpetrators. So, in this paper we will be discussing about such types of Date rape drugs which are being used at an extensive level in India, there mechanism that how they affect a person and its consequences.

ASSOCIATION BETWEEN ORAL LEUKOPLAKIA SMOKING AND ALCOHOL HABITS IN PATIENTS

Priyadharshini Suresh Babu; Deepika Rajendran; Geo Mani

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 1211-1220

Oral leukoplakia is seen as a predominant white patch in the oral mucosa and is the most common potentially malignant disorder of the oral mucosa. Habits such as tobacco, betel nut chewing and alcohol increases the incidence of oral leukoplakia. This study was aimed to evaluate the association of oral leukoplakia in patients having smoking and alcohol habits. In this study, patients having oral leukoplakia were sorted out by reviewing and analysing 86,000 patients records who visited the private dental college during the time period of June 2019 to March 2020. The personal history with habits such as smoking and alcohol were also recorded. A Chi-square test was used to determine association between variables to obtain the results. In our study, we found that the males showed higher prevalence of Oral Leukoplakia than females. A statistically significant result was found in patients between 41-50 years of age (29.2%) with smoking habits (84.8%) and alcohol intake habits (51%). It also showed that there was stronger association between oral leukoplakia and patients with both smoking and alcohol habits, than in patients having alcohol habit alone.