Online ISSN: 2515-8260

Keywords : potentially malignant disorder


ASSOCIATION BETWEEN ORAL LEUKOPLAKIA SMOKING AND ALCOHOL HABITS IN PATIENTS

Priyadharshini Suresh Babu; Deepika Rajendran; Geo Mani

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 1211-1220

Oral leukoplakia is seen as a predominant white patch in the oral mucosa and is the most common potentially malignant disorder of the oral mucosa. Habits such as tobacco, betel nut chewing and alcohol increases the incidence of oral leukoplakia. This study was aimed to evaluate the association of oral leukoplakia in patients having smoking and alcohol habits. In this study, patients having oral leukoplakia were sorted out by reviewing and analysing 86,000 patients records who visited the private dental college during the time period of June 2019 to March 2020. The personal history with habits such as smoking and alcohol were also recorded. A Chi-square test was used to determine association between variables to obtain the results. In our study, we found that the males showed higher prevalence of Oral Leukoplakia than females. A statistically significant result was found in patients between 41-50 years of age (29.2%) with smoking habits (84.8%) and alcohol intake habits (51%). It also showed that there was stronger association between oral leukoplakia and patients with both smoking and alcohol habits, than in patients having alcohol habit alone.

ASSOCIATION OF CLINICAL VARIANTS OF LEUKOPLAKIA WITH DIFFERENT TYPES OF TOBACCO - AN INSTITUTION BASED RETROSPECTIVE STUDY

Gayathri Karthikeyan; Hannah R; Jaiganesh Ramamurthy

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 1440-1448

The aim of this study is to assess the prevalence of leukoplakia in different types of tobacco users. Tobacco utilization in India is increasing but there are considerable changes in the types and methods by which it is used. Oral cancer affects as many as 274,000 people worldwide annually 20. In this study The data collection was carried out during the period between July 2019 to march 2020. After searching through 86,000 patient records the Sample size for the study was taken as 93 patients diagnosed with leukoplakia. The data that was collected was tabulated in excel and then imported into SPSS software. Smoking form of tobacco was found to be used by 72.92% of patients. Smokeless form of tobacco use was noticed among 25% of the patients and a combination of both smoking and smokeless form of tobacco used was noticed among 2.083% of the patients . Homogenous types of leukoplakia were found among 76.04% of the patients followed by the non-homogenous form which included about 23.96% of the patients. Males were the most common gender comprising about 96.88% of the patients and females comprised about 3.13% . It was also noted that the most common type of tobacco used was cigarettes. Chi- square test was done to associate the type of tobacco used and clinical variants of leukoplakia, it was not statistical significant (p=0.596). Within the limitations of the present study we were able to conclude that there was no association between the habit of tobacco use and the clinical variant of leukoplakia . Multicentric study with a larger sample size will give a more definitive outcome.