Online ISSN: 2515-8260

Keywords : Dermatitis

A study on identify the common allergens causing contact dermatitis article

B. M. Monisha, S Vinoth Kumar, Faheem Mubeen

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 9220-9228

Contact dermatitis is an inflammatory eczematous skin disease. It is caused by chemicals or
metal ions that exert toxic effects without inducing a T-cell response (contact irritants) or by
small reactive chemicals that modify proteins and induce innate and adaptive immune
responses (contact allergens).
Material and Methods
A total of 100 patients of contact dermatitis of either sex who attended the Out-Patient
Department of Dermatology, Venereology and Leprosy at Tertiary care teaching hospital
over a period constituted the subject material for the present study. Inclusion Criteria:
Patients clinically suspected to have contact dermatitis. Patients with active dermatitis were
first treated and then subjected to patch testing so as to avoid false positivity and excited skin
syndrome (Angry back syndrome).
Result: In our study males (51%) outnumbered females (49%) in the study. Itching was the
most common symptom (98%) followed by burning and oozing (10%). In this study, most
commonly observed period was 1-5 years, as seen in 57% of the cases. Study sensitization to
one antigen was seen in 40% cases, to two antigens in 27% cases, three antigens in 2% cases.
Negative results observed in 31 % cases. Positive patch test results were noted commonly
among the following occupations were labour (85.71%), farmer (66.66%), housewife
(62.96%), mason (53.33%) cases respectively. Cosmetic allergens (P<0.0001) significantly
more common in females. Parthenium (P<0.05) significantly more common in males.
In our study, the commonest allergens in our patients from hospital adjoining places were
potassium bichromate, thiuram mix and parthenium in males, whereas nickel, fragrance mix
and kumkum in females. In view of the differences in clinical patterns, positivity rates etc.
reported from different parts of India, we owe it to our patients to clarify the epidemiology of
this important problem.


Jv’n prof. Dr. M. P. Sharma m.d. (hom.); Jv’n dr. Rakesh sharmam.d. (hom.); Jv’n prof. Dr. Anil kumar vangani m.d. (hom.); Jv’n dr. Ravi jain m.d. (hom.); Jv’n dr. Alka jain m.d. (hom.); Jv’n dr. Gaurav gupta (hom.)

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 1233-1237

Under acute skin conditions there comes various ailments of skin like Eczemas,
Anaphylaxis, Atopy, Herpes Simplex, Photo-dermatitis, Seborrhoeic dermatitis, Miliaria,
Chilblains, DRESS reaction, AGEP reaction, Pompholyx etc. are a spectrum of the acute skin
conditions that affects human skin and manifests as erythema, eruptions, wheals, pustulosis and
often present with flaking or scaling skin or wheals, inflammation and pruritus. Homeopathy is
becoming one of the most popular management option for such conditions,and it is authenticated
via its principles- in Ancient Indian Literature and clinical trials are needed to test the efficacy, in
order to help community, Corporates and Government to create a policy to stoppage of work loss
and to improve the overall quality of living of it’s citizens/employees which will be observe b the
end of this study and further studies will be needed for the confirmation.