Online ISSN: 2515-8260

Keywords : Iron


Assessment Of Erythropoietin Efficacy And Dosing In Hemodialysis Patients

Mostafa Fawzy Mohamed Selim; Essam Eldin Mahmoud Lotfy; Lamiaa Abd Elwahab Mohamed; Mahmoud Hosny Zahran

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 2, Pages 2461-2469

Background: Anemia is a common complication in Chronic kidney disease (CKD) patients. It has a multi-factorial pathogenesis. Replenishing iron stores and giving ESAs are the main lines of treatment. There is a general agreement on the optimal route for iron supplementation in ESRD patients with the IV route but there is no such agreement on the optimal route for iron supplementation in pre-dialysis CKD patients. Erythropoiesis stimulating agents (ESAs) treatment represent an economic burden and has been linked to possible cardiovascular side effects. This study amid to assessing the efficacy of erythropoietin in treatment of anemia in CKD patients. Methods: A prospective cohort study was conducted in chronic kidney disease patients who had undergone hemodialysis in Met-Ghamr hospital of nephrology from February 2019 to July 2019. Included 50 patients on maintenance hemodialysis, we tested the efficacy through comparing the efficacy low fixed ESA dose (4000 IU IV once weekly) versus high fixed dose (4000 IU IV three times weekly). We divided group into two groups, group A and group B. group A were put on a fixed dose of 4000 IU Epoetin alfa once weekly and group B were put on a fixed dose of 4000 IU Epoetin alfa three times weekly. Results: After 6 months, We found a significant difference in hemoglobin response of the two subgroups in favor of subgroup IID (P = 0.004). Conclusion: That low dose ESAs is less effective in correction of anemia in dialysis patients than high dose ESAs.

RESULTS OF THE EFFECT OF COMPLEX TREATMENTS ON PERODONOT MICROCIRCULATION IN CHILD PERIODONTITIS WITH IRON DEFICIENCY

Alisher Norbutaev; Jasur Rizaev; Jakhongir Abduvakilov; Nargiza Ortikova

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 1680-1687

Abstract. The results of the effect of complex treatment on periodontal
microcirculation in patients with chronic periodontitis occurring with an iron deficiency
state.
Purpose of the study: to study periodontal microcirculation in patients with chronic
periodontitis occurring against the background of iron deficiency states.
Materials and methods: As the research sources, 100 patients who applied to the
Samarkand regional dental clinic suffering from chronic periodontitis and iron deficiency
were selected. The patients were divided into 2 groups, of which 1 main group consisted of
50 patients who received glycodent gel and an iron preparation (combined iron (II) sulfate
- sorbifer durules / ascorbic acid). The second group received the generally accepted
standard therapy for chronic periodontitis. The diagnosis of iron deficiency states was
established by determining the parameters of iron and ferritin in the blood.
Microcirculation was studied using the "Lazma" apparatus (Russia).
Results and discussion: A positive effect on microcirculation of the complex of
treatment with glycodent gel and an antianemic drug for chronic periodontitis with an iron
deficiency state was revealed.

Dates And Hemoglobin Levels: Literature Review

Dwi Ayu Rahmawati; Suryani As’ ad; A.Wardihan Sinrang; Ridni Husnah

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 2364-2370

Objective: The aim of this systematic review is to review studies on the effect of dates on increasing hemoglobin levels in anemia
Methods: the method used is an electronic database that has been published through the online libraries PubMed and Sciendirect. The keywords used for article searches are based on research questions. Result: a review of six health articles stated that dates are effective for increasing hemoglobin levels. Dosage, timing of administration, type of dates, food intake, a person's health condition should be of particular concern in giving date palm interventions. Not only increase hemoglobin levels, dates can also play a role in increasing ferritin, hematocrit, transferring saturation and serum iron levels in the majority of people.
Conclusion: dates can be used as an additional alternative to increase hemoglobin levels. However, disease or systemic syndrome in each person should be a concern because it can affect the effectiveness of dates in increasing hemoglobin levels.

Response Of Wheat To Foliar Application Of Iron At Different Growth Stages

Vicek .; C. M. Mehta

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 2443-2454

The experiment was conducted in Agriculture filed of Lovely Professional University, Jalandhar with wheat variety viz. HD 3086 to know the effect of foliar application of iron on nitrogen uptake and its combined impact on growth and yield of wheat. The plot design was RCBD with three replications and eight treatments. T1: Control (without fertilizer), T2: Control (with RDF), T3: RDF+ FeSO4 + Urea (at flowering stage), T4: RDF + FeSO4 (at flowering stage), T5: RDF + FeSO4 + Urea (at milking stage), T6: RDF+ FeSO4 (at milking stage), T7: RDF+ FeSO4 + Urea (at pre-maturity), T8: RDF + FeSO4 (at pre-maturity). The observed parameters plant height, length of spike, number of tiller, effective number of tillers, test weight of grain, number of spike lets per spike, number of grain per spike were taken at regular interval of 60, 90 ,120 DAS. In case of yield parameter the maximum test weight was recorded in T3 (49.75) and minimum was in T3 (45.09). For harvest index maximum value was recorded in T3 (45.42) and minimum in T1 (43.49). According to result, better growth and yield parameter was observed in treatments T3 due to foliar spray of iron and urea. Iron acts as catalyst and regulate many enzymatic activities which helps in better growth and increase in the yield, whereas urea is a source of nitrogen and in plants growth nitrogen play very important role because it helps in the synthesis of chlorophyll and many other activities.

Effect Of Foliar Application Iron Fertilizers On Nutrients Concentration Of Wheat Grain

Vivek .; C. M. Mehta

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 2455-2465

A field trail was conducted to evaluate the efficacy of foliar application of iron on nutrient availability in wheat grain. The plot design was RCBD with three replications and eight treatments. T1: Control (without fertilizer), T2: Control (with RDF), T3: RDF+ FeSO4 + Urea (at flowering stage), T4: RDF + FeSO4 (at flowering stage), T5: RDF + FeSO4 + Urea (at milking stage), T6: RDF+ FeSO4 (at milking stage), T7: RDF+ FeSO4 + Urea (at pre-maturity), T8: RDF + FeSO4 (at pre-maturity). After harvesting, estimation of nutrients in grain revealed that for most of the nutrients application of Fe at flowering and miliking stage has great impact on increased nutrients in grain.