Online ISSN: 2515-8260

Keywords : Antioxidants


Nuha ali Hadi; Abdulmonaim Hamad

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 9, Pages 105-110

The study aimed to find out the effect of type II diabetes on fucose and some values of antioxidants compared to healthy people, as 30 blood samples were collected from patients with type II diabetes, their ages ranged from 30-55 years, while 20 blood samples were collected from healthy people of the same age group and for both sexes., Where the fucose level was measured, a significant increase was found in the patient group by 0.01 compared to healthy people, and the efficacy of the enzyme catalase was measured, and a significant decrease was found at the probability level of 0.05. Also, glutathione recorded a decrease of 0.01 in patients with diabetes mellitus compared to healthy people, while vitamin C, Malondialdehyde and Peroxynitrite were recorded. An increase in the patient group compared to the healthy group at the 0.01 level. While vitamin A and Glutathione-S-transferase were increased in the group of patients compared to the healthy group, with the probability level 0.05. The study also included the measurement of urea, creatinine, uric acid and basic phosphatase. Urea, creatinine, and basic phosphatase all recorded an increase in the group of people with type II diabetes at a probability level of 0.01 compared to the healthy group, while uric acid recorded a significant decrease at the probability level 0.01. compared to healthy controls

Type of article : Review article Title of the article : ROLE OF BETA CAROTENE IN ORAL SQUAMOUS CELL CARCINOMA - A REVIEW

Dr. N. Aravindha Babu; Dr. G. Nishanth; Dr. K.M.K. Masthan; Dr. E. Rajesh

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 4, Pages 1476-1478

Oral squamous cell carcinoma (OSCC) is the most well-known malignant growth of the head and neck. It represents over 90% of all malignancies which happen in the head and neck region. The high frequency and mortality rate of oral cancer energizing continuation of exploration on finding new indicative diagnostic tools or markers for it. Oral squamous cell carcinoma (OSCC) is the 6th most common threat in the world. It is brought about by an assortment of elements, among which, oxidants, the results of typical digestion, rank high as a significant culprit in the development of the disease

Sterically Hindered Phenols as Antioxidant

Mankar Viraj H; Chhavi .

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 3481-3491

Hindered phenolics are the compounds which will act as an antioxidant compared to the general phenolic compounds. Especially BHT compounds are shown here and which modifications will be responsible for the enhancing and reducing the efficacy of the phenolic compounds. These moieties are easily avaliable materials which found mostly in the foods, fruits and vegetables and also in several suppliments. The free radical oxidation of organic substrates is inhibited by phenols.and also involved in recovering from several pathophysiological conditions.In this review mentioned the several phenolic compounds which exhibits the effect of scavenging free radicals in the several pathophysiological conditions and daily life processes.

Advanced treatment regimes and application of regenerative medicine for human male infertility treatment

A.S Vickram; G.V. Sree Charan; P. Venkatasaikumar; M. Kusuma; P.N. Ramya Bhargavi; G. Gulothungan; S. Thanigaivel; P. Jeyanthi; R. Nanmaran

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 5746-5766

Male reproductive organ and other assessory sex glands plays an massive role in sperm production process, sperm maturation process, maintaining the entry of sperm cells in the female reproductive tract and until child birth. Many events could happen properly from semen ejaculation until it reaches the oozyte for proper fertilization. Any problem during the process of semen reaching female reproductive tract could men responsible. Overall 20 to 35 % of men contribute to the infertility. Clinical evidence suggests that tissue engineering and regenerative medicine could help men achieve the fertility status. Congenital abnormalities, iatrogenic injuries, trauma and other chronic conditions could be treated by regenerative medicine. Recently stem cell therapy has been emerging in the file of male infertility treatment regimes. In case of trauma, penile reconstruction, testes reconstruction available as most advanced treatment regime. Here we summarized the important findings and functions of testes, penile and scrotum reconstruction techniques, organ based regeneration for various male infertile disorders. Non-obstructive azoospermia conditions will be very tough to diagnose and this review comprises the important treatment regimes available for non-obstructive azoospermia. Antioxidants therapy, trace elements therapy, oral administration of carnitines and its potential applications were carefully elucidated for idiopathic conditions. We also summarized the role of prebiotics and probiotics as treatment regime for male infertility. All advanced treatments methods available were in general summarized in this review.