Online ISSN: 2515-8260
Keywords : melаsma
RESEARCH ON POLYMORPHISM OF MATRIX METALLOPROTEINAS AND GROWTH FACTOR GENES IN PATIENTS WITH PHOTO AGING AND WITH MELASMA
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 2, Pages 1732-1736
In patients with a genetic predisposition, associations of the mutant variants
Arg25Pro of the TGFb1 gene, A-8202G of the MMP9 gene and MMP1 1607G (9.6%),
associations of the mutations of the Arg25Pro gene of the TGFb1 gene, and A-8202G of
the MMP9 gene (5.8%) are mainly detected, associations of mutations of Arg25Pro genes
of TGFb1 and MMP1 1607G (3.8%), associations of mutations of A-8202G genes of
MMP9 and MMP1 1607G (15.4%) of the examined patients with photo-aging.