Online ISSN: 2515-8260

Keywords : vibration


PECULIARITIES OF HYGIENIC ASSESSMENT OF WORKING CONDITIONS OF WORKERS ENGAGED IN OPENCAST AND UNDERGROUND MINING OF BROWN COAL AND IN UNDERGROUND MINING OF HARD COAL

Utkir Adilov

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 1799-1812

Abstract. Employees are working on opencast coal mining from May to September
work in conditions of heating microclimate. A decrease in the influence of the high
temperature of air and solar radiation is reached by the uniform distribution of the hottest
time of day (from 12 to 16 o'clock) by drawing up the working schedule. The selection of
means of individual protection of hearing organs, their regular use, and efficiency assessment
performance will reduce the impact of noise on workers' bodies. Decrease of total working
time in conditions of exposure to industrial vibration not exceeding 5-6 hours will allow
reducing the class of working conditions on this factor. The effectiveness of individual
respiratory protection means the size of dust particles, the degree of insulation of the
underwear space in places where the mask is not tightly attached to the face. Considering dust
dispersion, working conditions classes of workers engaged in brown coal mining in
underground mine #9 "Angrenskaya" decreased by 1 stage, while in mine "Shargunkumir"
the working conditions classes on dust factor, on the contrary, increased by 1 stage.

OCCUPATIONAL MORBIDITY OF WORKERS ENGAGED IN MINING OF DIFFERENT GRADES OF COAL

Adilov Utkir

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2722-2737

This work aimed to analyze professional morbidity in the coal industry of Uzbekistan.
The method of data copying from outpatient cards of professional patients and its statistical
processing was used for analysis. The professional morbidity rate in the coal industry was 108
cases per 10 thousand workers and 6.8 times higher than in other industries. At surface coal
mining in the open pit, as compared to underground mining in a coal mine, the number of
cases of first detected occupational diseases was, on average, 2.6 times lower. Thus, the
vibratory disease was most frequently met among workers of open-cast mining in comparison
with underground mining 1.4 times, and professional bronchitis, bronchial asthma and
pneumoconiosis - among workers of underground mining in comparison with open-cast
mining in 2.3 times.Vibration disease is diagnosed among workers of underground mines at
the work experience of 16 years, while among workers engaged in open-cast coal mining - 21
years and more. The analysis of results of medical and labor examination with professional
diseases of coal industry workers showed that among 48.3 ‰ of workers, there were 30.4 ‰
disabilities of Group III and 17.8 ‰ disabilities of Group II. These indicators had differences
depending on the brand of coal mined, so in the mining of brown coal (SiO2-10%), the
disability of professional genesis amounted to Group II 7.5 ‰ and Group III 31.3 ‰, while in
the mining of coal (SiO2-4%) 4.4 times more established Group II disability (73.3 ‰
workers) than Group III - (16.7 ‰). Conclusion: Coal dust of hard and lignite differ in
chemical and physical properties and degree of dispersion, which affects the level of
occupational morbidity and disability of workers.

BIOLOGICAL EFFECT OF INFLUENCE OF PLANT AND SYNTHETIC PREPARATIONS ON EXPERIMENTAL ANIMALS ORGANISM AT CHRONIC INFLUENCE OF PHYSICAL AND CHEMICAL FACTORS

Khamrakulova Mukaddaskhon .; Sabirova Gulchehra .

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2847-2862

Background:Experimental studies have confirmed the probability of
changes in some carbohydrate and protein metabolism indicators during
dichloromethane intoxication under the conditions of noise and vibration. It is
necessary to use Phytotea’ Gepalyuks’ with potassium for prevention and
treatment by correcting metabolic processes to avoid the adverse effects of
physical and chemical factors on the body.
Objective: Experimental study of the effectiveness of phytotea
“Gepalyuks” and potassium on carbohydrate energy metabolism of the liver and
blood under the influence of chemical and physical factors.
Methods: The experiments were conducted on 98 purebred white rats -
males weighing 160-180 years, contained in vivarium’s usual diet. Animals were
divided into control and experimental groups. Control animals received an
equivalent volume of drinking water, food and were kept in vivarium conditions.
Animals of the experimental group were divided into two groups: The first group
was intragastrically injected 10% of oiled dichloromethane solution in the dose of
1/20 LD50 (255 mg/kg) in conditions of noise (tape recording) at the level of 95-
105 dBA and vibration of 5-16 dBA during 90 days.
with intragastric administration of 10% oily solution of dichloromethane in a dose
of 1/20 LD50 (255 mg/kg), was administered a decoction of phytotea
“Gepalyuks”(1 ml of phytotea per 100 g of animal body weight) in conditions of
noise exposure (tape recording) at the level of 95-105 dBA and vibration of 5-16
dBA during 90 days. Phytotea “Gepalyuks” consists of immortelle sand flower,
yarrow herb, licorice root, peppermint leaves, corn snouts, and rosehip fruit.
Animals were slaughtered on 15, 30, 60 and 90 days from the beginning of the
experience. We took the liver, blood and determined biochemical indicators of
carbohydrate, protein, and pigment metabolism for research.
We studied some carbohydrate energy metabolism indicators to study the
effectiveness of phytotea“Gepalyuks” and potassium orotate under chronic
exposure to dichloromethane, noise and vibration.
Findings: When administered within 90 days, biologically active vegetable
and synthetic preparations in the form of decoction lead to an increase in the
activity of GDG, SDH and MDH and a decrease in the level of pyruvic and lactic
acids in serum and liver.
As a result of experimental studies, it was found that when administered
phytotea “Hepallux” in combination with potassium orotate for 90 days (15, 30,
60 and 90 days) under chronic exposure to dichloroethane, noise and vibration in
biochemical indicators - protein and lipid metabolism and activity of enzymes of
aliphatic amino acids remineralization (AST, ALT) and the content of cholesterol,
total and direct bilirubin in the liver and blood revealed a positive effect.
Conclusions: Application of phytotea “Hepallux” in complex
Potassium orotate causes a pronounced pharmacotherapeutic effect under
the toxic effects of chemical and physical factors - dichloroethane, noise and
vibration. Normalizes or approximates indices of carbohydrate energy (pyruvic,
lactic acids, the activity of GDG, SDG, MDG) metabolism and alkaline
phosphatase to those of the control group in blood and liver. The content of totalprotein, total and free bilirubins, the activity of AST, ALT in serum and liver is
approaching the norm.