Online ISSN: 2515-8260

Keywords : Coronary artery disease


Assessment of the risk factors and clinical profile of CAD in female patients

PranavAshokrao shende; S. K. Malani; Ravindra K. Jain; Chandrakant S. Upadhayay; Snehal A Shende; Vivek V. Manade

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 7130-7136

Background:Coronary artery disease (CAD) has emerged as the major cardiovascular disease of the era and also the commonest cause of premature death. For several decades, conventional invasive angiography (CIA) has been considered as the well-established gold standard for making the diagnosis of CAD. Hence; the present study was undertaken with the aim of assessing the risk factors and clinical profile of CAD in female patients. Materials & methods:A hospital-based descriptive observational study was conducted with 100 patients to evaluate clinical profile and angiographic pattern in women with Coronary Artery Disease. Baseline demographics, clinical and risk factor profile was collected. Disease is defined as presence of stable angina, unstable angina or myocardial infarction. Baseline demographics, clinical and risk factor profile was collected. Appropriate statistical software, including but not restricted to MS-Excel. SPSS version 20 was used for statistical analysis. Graphical representation was done in MS-Excel 2010.

Assessment of the profile of CAD patients: An observational study

Vivek Vilas Manade; Dr. S. K. Malani; C. Sridevi; Rajendra Patil; Shilpi Lahoty

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 7125-7129

Background:Cardiovascular diseases (CVD) and its complications account for approximately 12 million deaths annually in the Indian subcontinent. Hence; the present study was undertaken for assessing the profile of CAD patients. Materials & methods:A total 50 cases of CAD in young patients [age < or = 40 years] were studied. The cases were taken from medical, surgical, cardiology OPD, wards & ICU. The study population was a mix of urban and rural population. Both males and females were included in our study. The history of each patient was noted in detail and a thorough clinical examination was performed. Relevant investigations were performed in individual
case. Each patient was followed up until discharge and the final Outcome was noted – complications / recovery / death. Data analysis was done with the help of experts.

Association Of Spot Urinary Albumin Creatinine Ratio (UACR) With Coronary Artery Disease

Sanyukta H; A.H. Inamdar; Sunil Kumar

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 1962-1966

Background: Microalbuminuria has been recently found to be a marker of
atherogenesis. It is associated with various risk factors of atherogenesis and damage of the
vascular endothelium. There have been few studies in which it has been found that
mortality in cardiovascular disease are increased with microalbuminuria. Urine is
collected over 24 hours and this study has similar sensitivity as urinary albumin creatinine
ratio. A urinary albumin to creatinine ratio is as sensitive as a 24 hours urine study even
though it itself is a gold standard test. In patients with CAD other factors have been
explored then urinary albumin has been recently identified.
Objectives: To assess correlation between urinary albumin creatinine ratio with coronary
artery disease and to correlate Urinary albumin creatinine ratio (UACR) with
Framingham heart study Cardiovascular disease (FHS-CVD) score in all patients of
coronary artery disease.
Methodology: In this study which is cross sectional, Subjects to be included in the study
will be explained regarding the study and proper consent will be obtained. A random urine
sample will be collected. Urinary albumin concentration will be measured by auto analyser
and urine albumin creatinine ratio will be calculated. The values of the same will be
recorded and will be statistically analysed.

The Effects Of Smoking On The Relationship Between Estimated Glomerular Filtration Rate And The Severity Of Coronary Artery Disease Based On Syntax Score

Eko Irawan Sudarmaji; Hasyim Kasim; Pendrik tandean; Syakib Bakri; Faridin HP; Hae-rani Rasyid; Khalid Saleh; Arifin Seweng

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 1440-1449

Background: Chronic kidney disease (CKD) is an independent risk factor and caused high morbidity and mortality for coronary artery disease (CAD). Several scoring systems can be used in assessing the severity of CAD, one of which is using the SYNTAX score (SXscore). Smoking is one of the risk factors for the progression of CAD and CKD. Several observational studies have under-reported the smoking factor influencing the rela-tionship between eGFR and SXscore.
Methods: This research is an observational study with a cross-sectional approach conduct-ed at the Wahidin Sudirohusodo Hospital Makassar from July-August 2020. This study involved 62 CAD and CKD patients undergoing angiography. The estimated glomerular filtration rate was based on chronic kidney disease epidemiology collaboration (CKD-EPI).
Coronary angiography results were converted to SXscore and smoking grade based on the Brinkman index.
Results: This study involved 62 CAD and CKD patients male (71%), aged ≥ 55 years (77.4%), hypertension (71%), diabetes (35.5%), smoking (50%), eGFR G3a & G3b (53.9. %) and SXscore medium-high (50%). The results showed that lower eGFR could increase the SXscore (p < 0.001), especially in smoking subjects (p < 0.001). Multivariate analysis showed that gender was the most significant factor contributing to the relationship between eGFR and SXscore
Conclusion : The lower eGFR could increase the SXscore, where this correlation was more significant in smoking patients. Multivariate analysis showed that gender was the most significant factor contributing to the relationship between eGFR and SXscore.

New Trend Towards Healthy Fibre : Friendly Oats

B. Dhanalakshmi

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 6092-6095

Over the past few decades oats have become a very popular health food .Oats are loaded in dietary fibre (containing more than any other grain) and having a range of healthy cholesterol lowering properties. Recentstudies also have shown that oatmeal have some heart healthy benefits. This is mainly due to the rich source of water- soluble dietary fibres, particularly beta glucagon, that are found in oat meal. The U.S.Food and Drug administration claims that oats, as part of overall heart healthy diet, could lower the risk of heart disease. The potential health benefits of oats include: reducing the risk of coronary heart disease and lowering levels of cholesterol.