Online ISSN: 2515-8260

Keywords : Crisis


Fetal haemoglobin: A novel prognostic determinant in sickle cell anaemia

Dr. Obaid Noman; Dr. Arvind Bhake; Dr. Shweta Bahadure; Dr. Nihar Gupta

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2003-2008

Background-Acknowledgement of instrumental action of fetal hemoglobin(HbF)
in improving the clinical condition of sickle cell disease (SCD) patients, began around 7
decades back, by Janet Watson who found that infants with SCD had lesser symptoms and
their deoxygenated RBCs did not sickle or deform as aggressively as their mothers having
sickle cell trait. She proposed high HbF levels in infant blood as compared to mothers for
the observations of her study. Reduced incidence of crisis like vaso-occlusive, haemolytic,
aplastic, megaloblastic, infectious and others have been found with higher HbF levels.
With this backdrop the present study is being undertaken to know the reciprocity between
HbF levels and the state of crisis in sickle cell. The study is expected to fill the missing link
between “Why a few patients with HbS with haemoglobin pattern of SS suffer less from
crisis than that of others with a similar haemoglobin pattern of SS”
Objectives:
• To know HbF levels in pateints with SCD with Hb (SS) pattern
• To draw the comparisons between HbF levels in SCD with Hb(SS) pattern in
subjects 1. With sickle cell crisis and 2. Without sickle cell crisis
• To find out cut-off level of Hb F at its protective effect against the crisis in SCD
Methodology
• Study design - Observational and analytical study
• Sample size - Total of 30 Patients of sickle cell Disease (Hb SS)
• Study duration - 1 year
Expected Results: Incidence of Crisis in HbSS patients are expected to have a inverse
relationship with HbF levels. A cut-off level of HbF above which episodes of crisis are
lower can be expected to be found. Conclusion: Conclusions will be drawn from results
obtained and an attempt to establish a cut-off HbF value which renders a protective action
against crisis in SCD will be made.

Trauma Focused – Cognitive Behavior Therapy As An Innovation For The Prevention Of Trauma

Samsiah Mohd Jais; Mohammad Nasir Bistamam; Muhammad Bazlan Mustafa

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 4962-4971

This study aims to present the development result of the trauma focused – cognitive behavior therapy (TF-CBT) website and to test the percentages of agreement of the content, software interaction and technical aspects of TC-CBT website known as internet TF-CBT (iTF-CBT). The iTF-CBT module consists of five modules, namely i. Psycho Education; ii. TF-CBT; iii. Exposure Therapy; iv. Cognitive Therapy; and v. Anxiety Management. All of these modules are supported by 12 activities. Besides, this study is divided into two phases: i. Module development phase; and ii. iTF-CBT testing phase. The first phase involved data collection by conducting interviews with the experts as well as literature review. The second phase involved getting the percentages of agreement for the development of iTF-CBT among 42 trainee counsellors of the Sultan Idris Education University (UPSI). Results of this study indicate that the mean of percentages of the agreement between content, software interaction and technical aspects in the final test of iTC-CBT are high between 93 to 100 percents. These findings show that TF-CBT modules are applicable in the training to enhance efficiency of trauma and mental health counselling. As a result, this study has further expanded the theory and practices of counselling in the context of mental health particularly in Post Traumatic Stress Disorder (PTSD) and trauma.

Crisis Communication Management In Creative Economy Of West Bandung In Dealing With Covid-19 Pandemic

Antar Venus; Kismiyati El Karimah; HadiSuprapto Arifin; Meria Octavianti

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 3756-3771

Covid-19 pandemic greatly affected the growth of creative economy of West Bandung. Many creative economy workers had to stay at home for a while since they had nothing to do, and many creative economy players eventually went bankrupt since they could not run their businesses during the pandemic. The condition encouraged FEKRAF KBB, as the official organization that accommodates all creative economy players of West Bandung, to give a hand in dealing with and getting through the crisis during the pandemic. This study sought to reveal what crisis communication management that was employed by FEKRAF KBB in dealing with Covid-19 pandemic and how it was applied. Qualitative method with case study approach were used for resolving research questions. Observation, interview, focus group discussion, and literature review were employed to collect data. This study’s informants were the committee of FEKRAF KBB, the West Bandung Tourism and Culture Office, the representatives of creative economy players, the media and other stakeholders. The results showed that FEKRAF KBB correctly applied all principles and stages of crisis communication and utilized various communication channels relevant to the conditions of the crisis they faced. Crisis preparedness, initial respond, corrective and reaction, and evaluation were the stages of crisis communication they employed, andthe media they used were limited to on-line and social media. In regard to its implementation, FEKRAF KBB applied nearly all principles of crisis communication as follows: creating a communication team, engaging media, collecting facts, disclosing information, being one sound, and employing many communication channels.

A Critical Study Of Sir Vidiadhar Surajprasad Naipaul's "A House Of Mr. Biswas" And "The Mimic Men" In The Postcolonial Scenario

Harikumar Pallathadka

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 4535-4539

There is no doubting that the concept of identity crisis is the basic and primary concern in
postcolonial texts. With the onset of globalization, the movement of individuals from one
country to another has accelerated for various reasons. As a result, one can see the
creation of multicultural land with the concept of variety. When one considers Sir
Vidiadhar Surajprasad Naipaul (V.S. Naipaul)'s novels The Mimic Men and A House for
Mr. Biswas, one can see a sense of rootlessness and identity emerge. The current research
also examines how the protagonists attempt to build identities by overcoming their sense of
rootlessness in a colonial setting. Without a doubt, alienation and isolation are themes that
appear to permeate the current novels as you read them. This painting also portrays the
plight of indentured Indian laborers who traveled to the Caribbean islands in quest of
significance in their life. These books also look into the difficulties that these workers
faced and attempted to overcome.

An Examination Of Feminist Concepts In The Autobiography Of A Sex Worker By Nalini Jameela

Harikumar Pallathadka

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 4549-4553

Women make significant decisions during desperate situations and even choose to do odd
jobs to care for their families. Particularly Indian women put an end to their true identity to
care for their children. India is known for its various language and cultural practices.
Different languages are spoken across the country, their culture differs from state to state,
and their customs play a vital role concerning religion. They worship different Gods, yet
they remain united, so it is called the country of 'Unity in Diversity. Despite the differences,
all Indian women have specific common featured in them. Chastity is blended in the blood
of every Indian woman. They tend to protect it throughout their lifetime. However,
unfortunately, some women are pushed to the position where they have to sell their chastity
to provide for the family's sake. Even though the husband or the father is regarded as the
primary breadwinner, today, in so many Indian families, women take up the family
responsibility. They even choose to take up odd jobs such as surrogates and sex workers.
This paper deals with the bottled-up emotions of one such woman and the consequences of
the choice she made to take care of her family. The paper also argues the interconnection
between the feminist concepts that are taken up for analysis.