Keywords : Bromelain
COMPARISION OF EFFECT OF BROMELAIN AND ACECLOFENAC ON POST-OPREATIVE SEQUELAE FOLLOWING SURGICAL REMOVAL OF IMPACTED MANDIBULAR THIRD MOLAR – A CLINICAL TRIAL
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 2, Pages 2060-2069
Abstract: Background :. Impacted mandibular third molar removal is one of most
commonly practiced minor oral surgical procedure performed by oral surgeons. It causes
injury to the highly vascularized area, causing complications like pain, swelling and
trismus. Bromelain, a botanical enzyme leads to significantly decrease the sequalae after
removal of impacted third molar. Aim:. Comparison of efficacy of bromelain and
aceclofenac to reduce post-operative complications after removal of third molar. Material
and methods :Patients having impacted third molar selected for study. The sample
population is 72 and will be divided in 2 groups, each consisting 36 patients. Group 1 will
be prescribed with Bromelain capsules 250 mg TDS for 5 days and Group 2 will be
prescribed Tab. Aceclofenac BD for 5 days. The sequalae of mandibular third molar
surgery include pain, swelling and trismus is measured in two groups and data collected.
Expected Results : Student’s unpaired t-test will be analyse the data from the on 1st ,3
rdand 7 thday postoperatively . A comparison of both drugs will be achieved by unpaired ttest.
The variables include pain, swelling and trismus. When all the parameters will be
compared till six postoperatively, the bromelain shows significant results in reducing postop
complications like pain, edema and trismus in removal of impacted third molar.
Conclusion : Bromelain said to have greater efficacy than Aceclofenac for reducing
sequlae like pain, swelling and trismus after impacted third molar surgery.