Online ISSN: 2515-8260

Keywords : Clear margins


―Comparison of resection performed by Peroral and Transoral route on surgical margins in patients with oral squamous cell carcinoma.‖

Dr Chirag Sunil Patil; Dr. Anendd Arroon Jadhav

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2070-2078

Abstract: Backround: Lip-split incision has been traditionally used to manage the primary
oral cavity tumour to ascertain clear surgical margins. Small tumour excision is routinely
carried out per orally; however, there is a paucity of data vis-à-vis with the oncological
safety of per oral approach in T2/T3 excision of oral squamous cell carcinoma (OSCC).
Objective of the study: We compared per oral access over the transoral access in terms of
assessing the tumour free surgical margins. Settings & Design: A prospective,
interventional, double-blind, randomized control study was conducted among 20
histopathologically proven participants with previously untreated OSCC scheduled for
curative intent. Subjects & Method: Participants were randomly allocated to the two
intervention used. The primary outcome variables evaluated were the adequacy of the
surgical margin. Additionally, the primary tumour resection time between two
interventions was assessed. Results: The primary tumour resection time will be
significantly extended in Peroral access & no significant difference will be seen pertaining
to the adequacy of a safe surgical margin between two intervention. Peroral access will be
a choice of surgical approaches that preserve function, minimize complications and
maximize cosmetic outcome. Conclusion: Surgical approaches that minimalize
complications, preserve function with the optimal cosmetic outcome should be utilized
whenever feasible. Peroral access may offer significant advantages like avoiding transoral
trauma, fastens the healing time & affords better & faster recovery.