Online ISSN: 2515-8260

Keywords : ISCHEMIC STROKE


Relationship Between Serum Uric Acid Level And Ischemic Stroke In Patients With Type 2 Diabetes Mellitus In Nassiriyah City

ALYAA KAMIL RADHI, METHAQ ABDUL MAHDI HUSSEIN

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 2193-2202

Background: The role of serum uric acid as a risk factor for ischemic stroke in patients with type 2 Diabetes Mellitus is controversial and there is little information about it.
Aim of the study: This study was done to estimate serum uric acid levels in diabetic patients with ischemic stroke and to assess its risk factor potential.
Methods: It is a case control study carried out in the medical ward at Al Hussein Teaching Hospital at Al Nassiriyah city at southern of Iraq from June 2018 till December 2018, carried on 119 patient mean ages is 61.89 years. 56 of them was diabetic patients with ischemic stroke were enrolled as a case group and compared with 63 non diabetic patients presented with ischemic stroke also as a control group, Serum uric acid levels were measured in cases and controls (within 24 hours of stroke). The results were statistically analyzed and studied with other risk factors.
Results: Mean serum uric acid level in cases was 6.02 mg/dl where as it was 5.34mg/dl in controls. Hyperurecemia found in 25% of cases , with significant statistical association with increase in TG Cholesterol level p value is0.028 , and hyperurecemia was significant only in old age diabetic (p value less than 0.05) .
Conclusions: There was no significant statistical association between Serum uric acid level and stroke in type 2 DM, but it found to increase other risk factor for stroke especially in old age group , so it can be considered as a risk factor for ischemic stroke in type 2 DM.

A study of C-reactive protein in cerebrovascular accident (stroke) in a tertiary care hospital

Dr. Pinniboyana Vijaya Kumar, Dr. Pinniboyana Sri Harshitha, Dr. Gridhati Srinivas

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 1, Pages 1288-1293

Background: Stroke is the top cause of death and one of the leading causes of long-term
disability all over the world. hsCRP levels evaluated shortly after a stroke have been
demonstrated in studies to predict complementary elements of outcome. There's a
chance that high hsCRP levels are linked to the severity of cerebral tissue damage. We
wanted to see how high hsCRP levels were in people who had a cerebrovascular
accident. The goal was to see if there was a link between the level of hsCRP and the
severity of the stroke and the outcome.
Material and Methods: Patients hospitalised to a tertiary care hospital's (Narayana
Medical College Nellore) medical ward and medical ICU were studied. It was a crosssectional
investigation. The study involved a total of 100 patients who had a stroke and
met the study's inclusion and exclusion criteria. hsCRP levels were tested in all patients
within 48 hours of admission. Data was entered into a Microsoft Excel database
prospectively.
Results: The average age of the patients in the study was 59.12 years. Eighty-eight
percent of the patients were between the ages of 40 and 80. Also, values were found to
be higher in haemorrhagic stroke (value) than ischemic stroke (value), with a significant
difference. In both types of stroke, there was a significant association between hsCRP
levels and GCS, with lower GCS scores linked with greater hsCRP levels.
Conclusion: We concluded that hsCRP levels are elevated in both ischemic and
hemorrhagic strokes, implying an inflammatory response in acute stroke. Increased
hsCRP levels were linked to the degree of the neurological impairment and a worse
prognosis.

ANALYSIS OF THE SUBTYPES OF ISCHEMIC STROKE IN YOUNG AGE

Kim O.A .; Dzhurabekova A.T .; Shomuradova D.S .; Shmirina K.V .

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2509-2514

Abstract: Objective: to study the risk factors, clinical and pathogenetic features for the
subtypes of ischemic stroke at a young age in a comparative aspect. During 2017-2019, 74
patients with ischemic stroke (IS) or transient ischemic attack (TIA) were under
observation, 48 men and 26 women. All patients were divided into 2 groups: I-st (main)
group included 33 patients aged 20 - 44 years (aged of 40.5 ± 3.1 years); II-nd
(comparative) group - 41 patients age group over 60 years (aged of 67,9±3,9 years).
According to the TOAST criteria, a stroke of an unknown etiology occurred in young
people (49%), in old-aged - cardioembolic (39%) and atherothrombotic subtypes (31%).
Among the risk factors for ischemic stroke in young people revealed a combination of bad
habits, and in the old-aged category, such modulated factors as arterial hypertension, 2nd
type of diabetes mellitus, hypercholesterolemia are revealed. These findings confirm the
urgency of the problem of cerebral infarction of a young age and the need for further
implementation of the latest examination methods and a deeper study of the cardiovascular
system.

To The Question Of The Use Of Neuroimaging Examination In The Diagnosis Of Ischemic Strokes

MaksudovaKhurshidaNabievna .; MadjidovaYakutkhonNabievna .; Yuldasheva Manzura Muxamad- Tofikkizi; NurmukhamedovaMukhlisakhonAnvarkhodjaevna .; UsmanovaDurdona Djurabaevna

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 4523-4527

The relationship between the clinical picture of ischemic stroke and MRI in assessing changes in brain matter and cerebral hemodynamics was studied. It was found that changes in the venous circulation of the brain are detected on the MRI and MRI angiography and reveal a stable and reliable natural connection with different brain states and carry important information about the organization of its blood supply and identification of the degree and severity of vascular lesions.