Online ISSN: 2515-8260

Keywords : young age


CLINICAL, HEMODYNAMIC AND GENETIC ASPECTS OF THE DEVELOPMENT OF UNSTABLE VARIANTS ANGINA IN YOUNG MEN

Khasanjanova Farida Odilovna; Khaydarova Dilrabo Davronovna; Muradova Raila Rustamovna; Nuralieva Rano Matyakubovna; Nasirova Dilangiz Akbarovna

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 9, Pages 2123-2139

Recently, the prevalence of unstable variants of angina pectoris (NVS) among men at a young age has increased markedly. A significant role in the inflammation of the atherosclerotic plaque, which underlies the pathogenesis of NVS, is assigned to cytokines by the mediator. To date, the role of cytokine gene polymorphism in the development of NVS associated with inflammatory processes has been proven.

ANALYSIS OF THE SUBTYPES OF ISCHEMIC STROKE IN YOUNG AGE

Kim O.A .; Dzhurabekova A.T .; Shomuradova D.S .; Shmirina K.V .

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2509-2514

Abstract: Objective: to study the risk factors, clinical and pathogenetic features for the
subtypes of ischemic stroke at a young age in a comparative aspect. During 2017-2019, 74
patients with ischemic stroke (IS) or transient ischemic attack (TIA) were under
observation, 48 men and 26 women. All patients were divided into 2 groups: I-st (main)
group included 33 patients aged 20 - 44 years (aged of 40.5 ± 3.1 years); II-nd
(comparative) group - 41 patients age group over 60 years (aged of 67,9±3,9 years).
According to the TOAST criteria, a stroke of an unknown etiology occurred in young
people (49%), in old-aged - cardioembolic (39%) and atherothrombotic subtypes (31%).
Among the risk factors for ischemic stroke in young people revealed a combination of bad
habits, and in the old-aged category, such modulated factors as arterial hypertension, 2nd
type of diabetes mellitus, hypercholesterolemia are revealed. These findings confirm the
urgency of the problem of cerebral infarction of a young age and the need for further
implementation of the latest examination methods and a deeper study of the cardiovascular
system.