Online ISSN: 2515-8260

Keywords : hemodynamic

To Evaluate And Compare The Efficacy Of IV Esmolol And IV Lignocaine In Blunting The Hemodynamic Response To Laryngoscopy And Intubations.

Dr. Kuldeep Kumar Patel (Assistant Professor), Dr. Sanjay Kumar(Senior Resident), Dr. Vinod Kumar Singh Senger (PGMO)

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 2018-2023

Background&Method: The study was conducted with aim to evaluate and compare the
efficacy of IV esmolol and IV lignocaine in blunting the hemodynamic response to
laryngoscopy and intubationsat Sanjay Gandhi Medical College, Rewa, M.P. In the operating
room the patients was transferred to the operating table. An intravenous infusion with saline
0.9% was started using 18 G cannula in a peripheral vein. Blood pressure monitored by
manual cuff. A pulse oximeter was placed on the finger. ECG monitoring was also
established. A central venous line placed in the cubital vein using a 375 cava fix and a 0.9%
normal saline was started. Baseline heart rate and blood pressure were recorded. Random
allocation of patients to each group was done lots drawn by a person not taking part in the
study. The investigator that is the person doing the study was unaware of the drug used.
Result: The difference between the groups in distribution of age (p=0.6), weight (p=0.7) and
sex ( p=0.8) were not statistically significant. In duration of laryngoscopy and intubations was
not statistically significant. (P=0.5).In grades of laryngoscope was not statistically significant
(P= 0.51). In experience of anesthetist was not statistically significant. (P=0.37).
Conclusion: Esmolol and lignocaine are both similar in their effectiveness in attenuating the
haemodynamic response to laryngoscopy and intubation’s, but they do not abolish it
completely. More studies need to be carried out to confirm the perception that esmolol in
combination with the newer narcotic agents like fentanyl may abolish the haemodynamic
response to laryngoscopy and intubations, particularly required in the patients in whom a
single hyper dynamic response may be catastrophic.

A case report on electrical burn: below elbow amputation of left upper limb

Ms. Swapna Morey; Ms. Vaishali Tembhare; Savita Pohekar

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2627-2632

Abstract: Introduction: These injure result from contact with faulty electrical wiring g or
high voltage power lines passing over the residences. Lighting is also an electrical injure the
extent of injuring is influenced by the duration of contact, current-voltage, type of current
(direct or alternate) the path of current and the resistance offered by tissues. Case
Presentation: A case of a 25-year-old male admitted in the burn unit on the date 22 October
2019 with complaints about he came in contact with the electric pole due to electrical shock
on 12/10/2019. He had wound over left hand up the wrist, wound over over the left axilla,
inner part of both thighs, head and back. The wound over the left hand was associated with
pus discharge, which was foul-smelling and scanty in amount, blood-stained.Interventions:
Generally, the burn victims with major burns are hospitalized and care is providing the burn
unit or ward. The goals during this phase are saving a life, maintaining and protecting the
airway, restoring hemodynamic stability and promoting healing and preventing or correcting
the complication. Outcomes: Over the short course of treatment, the patient significantly
improved in functional mobility, transfers, ambulation, and bed mobility. Progress even
further towards his goal of returning home. Discussion: The patient responded well to
treatment, however additional interventions could be utilized in the future to aid in greater


Dhanshree Kale; Arachna Amol Gautam; Shraddha Naik; Avinash G. Bhosale; P. B. Patil; R. N. Mulla

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 4112-4117

A prospective, randomized study was performed after acceptance by the Ethics Committee and informed consent of 60 patients seeking elective surgery at the Krishna Hospital and the Medical Research Centre, Karad. The study objective is to evaluate haemodynamic consistency through attenuation of the pressure reaction during laryngoscopy and endotracheal intubation. Group A obtained pregabalin orally with water sips before induction and Group B served as control group, received multivitamin orally with sips of water 1hr before induction. Both groups were uniform in their distribution of age, weight and gender. They had similar physical status with no coexisting disease. Both groups were managed with same anesthetic protocol. It was concluded that the preoperative sedation before giving premedication in control and pregabalin groups are comparable, whereas pregabalin produced better preoperative sedation after one hour of premedication, as evidenced by higher Ramsay sedation score.