Online ISSN: 2515-8260

Keywords : Sonication


Investigation on hydrogen production from liquefied paper industry biomass using sonication homogenizer

Dr. K. Prasanna; Dr. B. Mahalingam; Dr.M. Kaarthik; Nasim Hasan; Gourav Kalra

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 3346-3355

The poor biodegradation of liquefied biopolymer extricate and faster ingesting of hydrogen
gas, hydrogen production from control sample (raw waste biomass) with seed sludge
practicability is limited. In the present study, hydrogen gas generation potential of paper
industry waste(PIW) biomass was studied using sonication. During sonication mediated PIW
biomass pretreatment, power input and specific energy were varied for liquefied biopolymer
extricate. At optimum power (175 W) and specific energy (30667kJ/kg TS), sonication
method obtained 2330 mg/L of liquefied biopolymer extricate during PIW biomass
pretreatment. Then, the substrates namely sonication pretreated PIW biomass and control
(raw PIW biomass) were subjected to hydrogen assay. At 384 h of digestion, sonication
method got a maximal hydrogen production (17 mL/g VS) compared to control (3.8 mL/g
VS).Therefore, sonication mediated PIW biomass helps to diminish the biomass generation 
by ameliorate the complex biopolymer liquefaction for boosting hydrogen production at large
scale.

“An Efficient Synthesis Of Substituted Isoxazole Derivatives Using Ultra Sound Sonication Method”

Rajiv Khobare; Ramkrushna P Pawar; Khandu D Warad; Amit Tayade; Chandrakant B Mane

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 319-325

A series of synthesis of some substituted isoxazole derivatives using efficient ultra sound sonication method in methanol solvent. Firstly the synthesis of different substituted chalcones using substituted aldehydes and substituted acetophenones using triethylamine as base in ethanol solvent under sonication. In second step synthesized substituted chalcones is reacted with two equivalents of hydrochloride salt of ammonium hydroxide, sodium oxalate and methanol under sonication at 30-35OC to afford a substituted isoxazole derivatives in 90-98% of yields. The structures of the synthesized compounds were confirmed on the basis of NMR, and MS analysis. This method has a several advantages over current reaction methodologies, such as shorter reaction times, simple work-up procedure and good percent yields.

The Use of Sonication Method For Reducing Size of Liposomes In Papaya Leaf Extract (Carica Papaya Linn) Preparations As A Candidate In Treatment of Cervical Cancer

Yuly Peristiowati; Sandu Siyoto; Koesnadi .; Arina Chusnatayaini; Hariyono .

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 1011-1016

Liposomes are vesicle-shaped particles whose walls are composed of lipid molecules ( the main constituent is a double layer phospholipid which wraps the liquid compartment inside. Liposomes can be made from natural ingredients in the form of natural phospholipid derivatives mixed with fat chains (eg phosphatidylcholine) by dispersing. Liposomes from papaya leaf extract (Carica Papaya Linn) are made with the aim of increasing the effectiveness of the drug and biocompatible work, as well as protecting healthy tissue from the toxic effects of the drug. The process of making liposom papaya leaf extract using the sonication method by mixing soybean lecithin with papaya leaf extract. Then do the heating and sonication. This method is done to reduce particle size. The aim of this study was to produce an extract of liposomes from papaya leaf phospholipid formulations using a combination of heating and sonication.The method to produce liposomes with a size of <150 nm using a combination of heating 40○C for 40 minutes and stirring using ultraturrax at a speed of 15,000 rpm for 30 minutes, then stirring with a sonicator for 30 minutes.The results showed the liposome nano papaya leaf extract formulation from soybean lecithin by the PSA (Particle Size Analyzertype 1090 / Cilas) method. The liposome product was in the form of liquid, light green and milk white and odorless. Particle size distribution is obtained in the range of 0.04 μm - 500.00 μm / 100 Classes and an average pH of 5.45.

The Use Of Sonication Method For Reducing Size Of Liposomes In Papaya Leaf Extract (Carica Papaya Linn) Preparations As A Candidate In Treatment Of Cervical Cancer

Yuly Peristiowati; Sandu Siyoto; Koesnadi .; Arina Chusnatayaini; Hariyono .

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 4703-4709

Liposomes are vesicle-shaped particles whose walls are composed of lipid molecules ( the main constituent is a double layer phospholipid which wraps the liquid compartment inside. Liposomes can be made from natural ingredients in the form of natural phospholipid derivatives mixed with fat chains (eg phosphatidylcholine) by dispersing. Liposomes from papaya leaf extract (Carica Papaya Linn) are made with the aim of increasing the effectiveness of the drug and biocompatible work, as well as protecting healthy tissue from the toxic effects of the drug. The process of making liposom papaya leaf extract using the sonication method by mixing soybean lecithin with papaya leaf extract. Then do the heating and sonication. This method is done to reduce particle size. The aim of this study was to produce an extract of liposomes from papaya leaf phospholipid formulations using a combination of heating and sonication. The method to produce liposomes with a size of <150 nm using a combination of heating 40○C for 40 minutes and stirring using ultraturrax at a speed of 15,000 rpm for 30 minutes, then stirring with a sonicator for 30 minutes. The results showed the liposome nano papaya leaf extract formulation from soybean lecithin by the PSA (Particle Size Analyzertype 1090 / Cilas) method. The liposome product was in the form of liquid, light green and milk white and odorless. Particle size distribution is obtained in the range of 0.04 μm - 500.00 μm / 100 Classes and an average pH of 5.45.