Online ISSN: 2515-8260

Keywords : Regenerative Endodontics


A comparative evaluation of PRF, blood clot and collagen scaffold in regenerative endodontics

Sravani Uppala

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 3401-3410

Aim:The present study was conducted evaluate the efficacy of revascularization procedures
for the management of traumatized immature, nonvital, infected permanent teeth.
Materials & Methods:24 adult patients age ranged 13-24 years of both genders with
immature necrotic permanent teeth were classified into 3 groups of 8 each. Group I used
platelet rich fibrin (PRF). Group II used blood clot and group III used sterile collagensponge
scaffold. Patients were recalled regularly and clinical and radiographic evaluation was
performed at 6 months and at 1 year.
Results:In group I, 20% teeth had good and 80% had excellent healing, in group II, 20% had
fair, 50% had good and 30% had excellent healing and in group III, 70% had good and 30%
had excellent healing. In group I, 90% teeth had fair and 10% had good root lengthening, in
group II, 20% had fair and 80% had good root lengthening and in group III, 71% had fair and
29% had good root lengthening. None of the group had excellent root lengthening. Apical
closure was good in 40% and excellent in 60% in group I, good in 25% and excellent in 75%
in group II and fair in 30%, good in 30% and excellent in 60% in group III. Dentinal wall
thickening in group I was fair in 30% and good in 70%, in group II, 50% had fair and 50%
had good and in group III, 30% had fair, 50% had good and 20% had excellent response.
Conclusion:Authors found that PRF and collagen was superior than blood clot in terms of
apical closure and healing. Regenerative healing with different scaffolds is useful method of
preserving immature non- vital permanent teeth.

Coronal Pulpotomy Technique Analysis As An Alternative To Pulpectomy For Preserving The Tooth Vitality In Context To Tissue Regeneration: A Correlated Clinical Study Across 4 Permanent Molars

Dr. Shridhar Shetty; Dr. Suneetha. M; Dr. Shinaz Mittal; Dr. Krishna Vallabhaneni SS; Dr. Sandeep Dande; Dr Sonal Kothari; Dr. Heena Tiwari

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 5255-5262

The purpose of our research was to assess the prognosis of the treatment performed using second generation platelet concentrates (PRF) and a new calcium silicate-based material (Biodentine) for coronal pulpotomy techniques.
Methodology: Pulpotomy procedure was carried out on 4 carious involved, permanent molars detected with acute irreversible pulpitis in 17- to 22-year-old patients. Taking into consideration the patient’s age and the condition of the underlying pulp tissue, PRF pulpotomy was planned in view of preserving the vitality of the intact radicular pulps. Regenerative procedures with second generation blood matrices were chosen to encourage
the recovery of the inflamed pulps. The follow-up examinations were conducted at 6, 12 and 24 months, revealing a better clinical and radiological result. Descriptive analysis was carried out to assess the prognosis all these teeth with subsequent follow ups.
Results: The clinical follow-up evaluation of the cases was met with a positive outcome. In addition, the digital radiographic examination (RVG) of the cases revealed an intact PDL space and a normal trabecular pattern of the bone. There was statistically significant dentinal barrier formation, which shows the healing reponse.
Conclusion: We can conclude that clinicians can safely rely upon advanced non-invasive, regenerative approaches to improve the standard of care delivered to the patients and can be considered as an alternative to conventional RCT.