Online ISSN: 2515-8260

Keywords : Diabetics


Comparison of peri implant soft tissue and crystal bone status of dental implant placed in pre diabetic, diabetic and non-diabetic individuals

Dr. Pradnya Rajendra Khatavkar; Dr Krishna P Biswas; Dr Pritesh Gangde; Dr. Amit Kumar Mishra; Dr Rashmi Laddha; Dr Reshma Avhad

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 1, Pages 875-879

Background: The present study was conducted to compare peri implant soft tissue and crystal bone status of dental implant placed in pre diabetic, diabetic and non diabetic individuals.
Materials & Methods: 60 patients were divided into 3 groups. Group I were pre diabetic (HbA1c 5.5 to 6.4%), group II were patients with poorly controlled type 2 DM (HbA1c ≥ 6.5%) and group III were healthy individuals (HbA1c < 5.7%). In all patients, peri-implant GI, PD and plaque index (PI) were measured.
Results: In group I, there were 12 males and 8 females, in group II were 10 males and 10 females and in group III, 9 males and 11 females. The mean plaque index in group I was 2.7 in group II was 3.1 and in group III was 0.5, gingival index was 2.9 in group I, 3.4 in group II and 0.6 in group III, probing depth was 4.1 in group I, 4.8 in group II and 1.2 in group III, crestal bone loss on mesial side was 3.6 mm in group I, 4.2 mm in group II and 0.7 mm in group III and crestal bone loss on distal side was 3.7 mm in group I, 4.0 mm in group II and 0.8 mm in group III. The difference was significant (P< 0.05).
Conclusion: Chronic hyperglycemia increases the risk of peri-implant diseases, there a good glycaemic control is necessary to prevent it.

Analysis Of Thyroid Profile In Type-2 Diabetes Mellitus Patients

Abdur Rahim Abidi; Ravjit Kaur Sabharwal; Niamatullah Zaheer; Pranav Kumar Prabhakard

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 4383-4390

Diabetes mellitus and thyroid gland abnormalities are interlinked and coexist with influencing each other. Current study was planned and conducted to evaluate thyroid status in patients with type-2 diabetics. The main aim of the study was to understand the relationship between diabetes mellitus and thyroid abnormalities. Total 100 known diabetic patients were studied, out of them 37 were males with the mean age 59.81 ± 12.8 years, and 63 females with average age of 55.31 ±11.10 years. 50 non-diabetic healthy subjects included 13 males and 37 female of mean age 48.86 ± 12.9 and 48.86 ± 17.94 years respectively selected as a control. All the patients were evaluated for thyroid profile (TSH, FT3, and FT4) and diabetic profile (RBS and HbA1c) by using Cobas C-311 and Cobas E-411 fully automated immunoassay analyzer. The observations were recorded. The result showed that, out of 100 diabetic subjects 41.03% male and 58.97% female were faced with euthyroid and the remaining 22% had thyroid dysfunctions. Hypothyroidism was more common in females (78.97%) as compared to men (21.05%). The mean values for TSH, FT3 and FT4 at (p> 0.05%) probability level shows statistically no significant difference. The relationship between diabetes and thyroid abnormalities was significantly difference, interdependency of these two conditions and evaluation of thyroid hormones status with the diabetic profile in the early days of diabetes is recommended. This will induce the management strategies of diabetes and can delay and avoid the progression of the secondary complications in diabetic patients with uncontrolled diabetes.

Comparison Of Peri Implant Soft Tissue And Crystal Bone Status Of Dental Implant Placed In Pre Diabetic, Diabetic And Non-Diabetic Individuals

Dr. Pradnya Rajendra Khatavkar; Dr Krishna P Biswas; Dr Pritesh Gangde; Dr. Amit Kumar Mishra; Dr Rashmi Laddha; Dr Reshma Avhad

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 6936-6940

Background: The present study was conducted to compare peri implant soft tissue and crystal bone status of dental implant placed in pre diabetic, diabetic and non diabetic individuals.
Materials & Methods: 60 patients were divided into 3 groups. Group I were pre diabetic (HbA1c 5.5 to 6.4%), group II were patients with poorly controlled type 2 DM (HbA1c ≥ 6.5%) and group III were healthy individuals (HbA1c < 5.7%). In all patients, peri-implant GI, PD and plaque index (PI) were measured.
Results: In group I, there were 12 males and 8 females, in group II were 10 males and 10 females and in group III, 9 males and 11 females. The mean plaque index in group I was 2.7 in group II was 3.1 and in group III was 0.5, gingival index was 2.9 in group I, 3.4 in group II and 0.6 in group III, probing depth was 4.1 in group I, 4.8 in group II and 1.2 in group III, crestal bone loss on mesial side was 3.6 mm in group I, 4.2 mm in group II and 0.7 mm in group III and crestal bone loss on distal side was 3.7 mm in group I, 4.0 mm in group II and 0.8 mm in group III. The difference was significant (P< 0.05).
Conclusion: Chronic hyperglycemia increases the risk of peri-implant diseases, there a good glycaemic control is necessary to prevent it.

Estimation Of Salivary Alkaline Phosphatase Levels In Smokers And Tobacco Chewers Associated With Diabetes

Sushmitha M; Preethi. M; B. Sivapathasundaram

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 119-128
DOI: 10.31838/ejmcm.07.05.12

Background:- Alkaline phosphatase is the group of hydrolytic enzymes that are involved in the cellular metabolism. Alkaline phosphatase in saliva is used as an indicator of gingival inflammation, bone metabolism and other oral lesions like premalignancies and oral cancer.
Aim and objective: To estimate the levels of Salivary Alkaline Phosphatase (S-ALP) in smokers and tobacco chewers associated with diabetes and diabetics without any habits.
Materials and Methods: The study includes 30 cases and 10 control. 30 cases divided in group A, B and C and control group D: (1) Group A - 10 smokers who are diabetic. (2) Group B - 10 tobacco chewers who are diabetic. (3) Group C - 10 nonsmokers and non-tobacco chewers who are diabetic. (4) Group D - 10 nonsmokers, non-tobacco chewers and nondiabetic as control. Saliva was collected from the subjects of the above mentioned groups and the levels of S-ALP were estimated using a semi auto- analyzer and comparison was made.
Results: The result reveals increase in the alkaline phosphatase levels in saliva of smokers and tobacco chewers with diabetes group (Group A, B). Non-smokers and non-tobacco chewers with diabetes group (Group C) had higher level compared to the control group (Group D).
Conclusion: Salivary alkaline phosphatase is a clinical biomarker that is used to determine the oral diseases due to adverse habits and diabetes at its early stage.