Online ISSN: 2515-8260

Keywords : Gestational Age


Role of fetal renal length measurements in estimation of gestational age

Dr S.Swetha Reddy, Dr M. Laxmi

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 10340-10349

Introduction: For the management of obstetric cases, it is very important to know the
EDD. But in our set up most of the women do not know the date of LMP and hence it is
difficult to predict the EDD. Therefore, ultrasound examination plays an important role
in determining the EDD.
Aims: To formulate the ideal length of fetal kidney to the corresponding gestational age
and to study of echo pattern of fetal kidney and its correlation with pregnancy outcome.
Materials and methods: 200 pregnant women with known LMP were taken for the
study. Gestational age by LMP was calculated and it ranged from 20 weeks to 40 weeks.
All the cases were subjected to ultrasound examination. Besides other information
through USG, special emphasis was made to calculate USG gestational age by
conventional method of measuring BPD. FL. AC. At the same time the renal length and
renal medullary echo pattern was examined in all the cases. The cases were grouped
according to the gestational age by LMP and mean renal length was calculated for each
gestational age group.
Results: It was observed that there was a wide variation in renal length for the
gestational age group of 20-30 weeks. This variation narrowed down from the 30-40
weeks of gestational age group. There was a definite correlation between the renal
length with the gestational age by LMP. It was found that USG with standard
parameters gave ± 3 weeks difference form LMP EDD, whereas the EDD calculated by
renal length gave a difference of ± 2 weeks. The prediction interval was narrowed from
±3 weeks to ± 2 weeks when renal length was used instead of the standard USG
parameters i.e., there was ± 1 week difference between EDD by renal length and EDD
by USG.
Conclusion: Examination of fetal renal medullary echo pattern helps us in identifying
high risk pregnancy associated with intrauterine growth restriction and helps us in
management decisions.

Clinical Study of Neonates Born to Mothers with Hypertensive Disorders of Pregnancy (HDP)

Gajula Ravi, Janardhan Reddy Pulluru, Suraboina Satishkumar

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 10414-10423

Background:Globally, hypertensive disorders of pregnancy (HDP) are one of the major
causes of perinatal and maternal morbidity and mortality. These disorders are
characterized by increase in blood pressure (BP) which may be present before or
appear for the first time during pregnancy after 20 weeks with or without proteinuria
or evidence of multiorgan involvement and have been classified into preeclampsia (PE)
and eclampsia syndrome, chronic hypertension (CH), PE superimposed on CH, and
gestational hypertension. The HDP may complicate 5%–10% of all the pregnancies
with the prevalence of 6.9%–7.9% in India. Studies have shown that HDP accounts for
around 16% of 2.6 million stillbirths and 15% of perinatal deaths globally. Higher rates
of adverse perinatal outcome such as preterm delivery, low birth weight, birth asphyxia,
stillbirth, and early death have been reported worldwide in women having
HDP.Prematurity and preterm birth are documented as the most common cause of
perinatal death in Indian women with HDP. The present study was conducted with the
aim to know the type of hypertension affecting the pregnant women and perinatal
outcome.Aims and objectives:To determine the outcome of neonates born to mothers
with Hypertensive Disorders of pregnancy in comparison with neonatal outcome in
babies born to normotensive mothers.
Materials and Methods: A comparative case control study will be performed on
Neonates fitting into inclusion criteria from JAN 2019 to Jun 2020 and a
prestructuralperforma will be used to obtain detailed History taking, Clinical
examination .The comparison will be done between two groups. The study group, which
will include neonates born to mothers with either gestational hypertension,
preeclampsia or eclampsia. The control group, which will include all babies born to
normotensive mothers, matched forgestation with the study group during the study
period.
Results: The results showed that the primary and the secondary outcomes in the study
group was significantly poorer compared to control group. There was significantly high
rate of death among the neonates born in the study group (p< 0.05).Also there was
higher rate of meconium stained amniotic fluid (16%), more requirement of surfactant
(14%) and more requirement of NICU admission (31%) among the study group. There
was also higher rate of IUGR (20%) as well as higher rates of Low birth weights among
study group.

CHARACTERISTICS OF HEMOSTASIS DEPENDING ON HEMORRHAGIC AND ISCHEMIC BRAIN DAMAGE IN PREMATURE NEWBORNS

MadjidovaYakutkhon Nabievna; AkhmedovaZiyodaShakhabiddinovna .; AzimovaNodira Mirvasitovna; NasirovaDilfuzaShavkatovna .; KhalilovaAliyeEmirasanovna .; AmritdinovaFarangizShakhabiddinovna .; BakhramovMakmudjonSaydullo ugli .

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 2, Pages 1130-1133

In this article, some indicators of the hemogram in premature newborns are studied. The analysis and comparison of the obtained indicators in children with hemorrhagic and ischemic lesions of the central nervous system was carried out. Small distinctive features were revealed in intraventricular hemorrhage and cerebral ischemia

The Use Of Abdominal Aorta Length In The Fetuses’ After 34 Weeks Of Gestation For Calculating Gestation Age Among Primigravida Healthy Women

Dr Najlaa Hanoon; Dr Wisam Akram

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 139-149

Aim of the stud; To verify the correlation between abdominal Aorta Length in the fetus and gestational in weeks between 34- 40 weeks
Type of study; Case Control
Methods; a healthy pregnant women were chosen who’s age between 15-40 years all are primigravida and conceived within 3 months of marriage. They were between 34- 40 weeks in gestation. Their last menstrual period was know and recorded in addition all were scheduled for ultrasound examination for measurement of the abdominal aorta length, femoral length and biparietal diameter.
Result; a highly significant correlation was found between abdominal aorta and biparietal diameter and femoral length . In addition a highly significant correlation was found between gestational age calculated by their LMP and abdominal aorta. In addition a highly significant correlation was found between gestational age and abdominal aorta length. A non linear exponential equation was constructed with lowest mean of sum of squares=1, and coefficient of correlation= 0.97 between abdominal aorta length and gestational age in weeks. From this equation a reference table built which contains value for the abdominal aorta between 34- 40 weeks for 1,2.5,5,10,90,95, and 99 centiles. After the building of this table further 35 women were taken for assessment of this table. Only 2 were miss calculated, the Kappa Cohen coefficient=0.93
Conclusion; a table by which the gestational age can be calculated between 34-40 weeks by measuring the abdominal aorta. However under no circumstances this table may be used apart from assessment applications. Further studies are required to verify its accuracy