Online ISSN: 2515-8260

Keywords : aspartate aminotransferase (AST)


CHANGES IN BIOCHEMICAL PARAMETERS IN PATIENTS WITH HEMOPHILIA WITH MUSCLE HEMATOMAS BEFORE AND AFTER TREATMENT

Madasheva. A G.; Maxmudova A D.; Dadajanov. U.D.; Yigitov. A.U.; Shomirzaev. X.M.

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 2, Pages 2142-2149

This article we discussed about biochemical changes in blood hemophilia A is a worldwide disorder of the coagulation system. It is a male disease, but women with hemophilia are less common in communities with high levels of kinship. There are steps to achieve an optimum life for patients with hemophilia in developing countries, and awareness of the pattern of death in patients with hemophilia is a prerequisite for any health-care program. Owing to the lack of any data on the pattern of death in patients with hemophilia from developing countries, the current study was done to address common causes of death, and the spectrum of causes of death among individuals with hemophilia A and B.

Electrolytes System Disorder And Liver Enzyme Alteration In Adult Men With Hepatocellular Injury

Alzahraa Ibrahim Abdulmajeed; Wafaa Sh. Al – Zuhairi; Ekhlas Abdallah Hassan

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 6, Pages 805-812

Objective: The current study aimed to estimate the magnitude of liver hepatocellular damage in adult men suffering from advanced stages of liver infection considering various important variables (age, BMI, TSB, DSB, GOT, GPT, Na+, K+, Cl-). Background: The main cause of hepatocellular injury is viral hepatitis C. Development of this disease leads to transformation of normal liver tissue into fibroses and nodules (cirrhosis), and it is associated with numerous complications, including gastrointestinal bleeding, ascites, renal function disorder and electrolyte disturbance. Method: The sera of all participants, including 25 patients with VHC and 15 cirrhotic patients, were collected for comparison with 23 control donors (healthy men). The present study was conducted in Baaqubah General Hospital/Diyala. Serum electrolyte concentrations were measured by spectrophotometry assay. Results: significantly decreasing sodium concentration in cirrhotic patients and statistically increasing chloride concentration in patients with liver disease compared with the control (P value < 0. 05). Furthermore, a number of disorders that effect of the liver enzymes levels, Conclusion: The essential decrease in sodium (Na+) concentration was observed in cirrhotic men caused by reduction in renal perfusion. This result is in contrast to that of serum chloride, which increased in patients with liver diseases.