European Journal of Molecular & Clinical Medicine

Aim: To evaluate the Prevalence of anxiety and depression during COVID-19 pandemic.
Methods: This study was conducted during the Coronavirus outbreak. Following
development by the research team, the online survey was tested during these study periods.
100 participants were included in this study.
Results: 40% of participants reported feeling tight or wounded up from time to time
(sometimes), whereas 23% reported feeling this way all of the time. Many (35%) were
worried as if something terrible was going to happen, but 'not too severely,' while 33 percent
felt frightened 'a bit' as if something terrible was about to happen, but it did not bother them.
Many people (38 percent) had anxious thoughts from time to time, while others (24 percent)
had them all the time. Only 41% said they sat at ease and felt calm "generally," while others
said they didn't sit at ease and felt relaxed "very frequently" (33 percent ). More than half of
the students (55%) reported not being afraid or having a 'butterfly' feeling in their stomach,
whereas many others (24%) had that scared emotion 'sometimes.' Only 15% of the
participants reported being restless and on the move. In terms of experiencing a sudden sense
of panic attacks, just a small percentage (9%) reported having had this 'often' or 'very
frequently' (20 percent ). When asked if they still enjoyed the things they used to appreciate,
just 36% said they didn't enjoy them as much anymore. Only half of the students (50%) said
they could laugh and see the funny side of things "as much as they always could." A fresh
look at the participants' emotions indicated that just 47 percent of them felt joyful'sometimes,'
while others felt cheery 'not often/not at all' (24 percent , 14 percent respectively).

Covid-19 i.e Corona Virus is well aware to the world every corner. It is pandemic, epidemic. People are panic. Educational Institutes like schools, colleges , roads, businesses, transport, companies almost all closed except necessary things like Medical shops, Vegetables. Changing lock down and sealdown rules by central and state Governments according to the situation in their areas, geographical restrictions, movement restrictions done based on the spread of COVID-19 in that area. Government is order to stay at home safely. This paper tries to assess the level of awareness on COVID-19, its spread, precautions taken by people, social distance and few inputs; by that it is possible to understand the ground realities of people for taking action and making policies and strategies for removal of COVID-19.

Background of the Study: Bacterial and Viral infections are often hard to be distinguished in daily clinical practice. Biological markers obtained from a routine examination play an important role to minimize time in providing diagnose and giving therapy. Recently, the use of Neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), and platelet-lymphocyte ratio (PLR) is greatly considered to differentiate types of infection found in the patients presenting with fever.
Method: This study uses prospective cohort study design and involves patients presenting with fever who are admitted to the ICU. The initial NLR, MLR, and PLR is examined and categorized into types of infection found. The ANOVA test and t-test are performed to find out the difference among study groups with the value of α = 0,05.
Result : This study involves 207 patients (92 male patients [44%]) presenting with fever with the average age of 45,6 ± 14,6 years old. The majority of cases (135 cases [66,5%]) in patients with fever results from bacterial infection; The study also finds 47 cases (34,8%) of typhoid fever and 30 cases (22,2%) of pulmonary tuberculosis. Dengue hemorrhagic fever (DHF) is the most commonly found viral infection with 52 cases (76,4%). The significant diagnose of bacterial infection shows higher value of NLR and MLR than that of viral infection (P < 0,001); Urinary tract infection has the highest value of NLR and MLR, amounting to 9,4 ± 3,6 and 0,23 ± 0,20, respectively. In general, the value of PLR is lower than that of viral infection (P < 0,001).
Conclusion: Neutrophil-lymphocyte ratio, MLR and PLR have benefit to predict diagnosis for the patients presenting with a fever. Bacterial infection is associated with the high value of NLR and MLR, and PLR generally has a lower value in viral infection cases.

from this article we see that why COVID-19 causes thrombosis, A thrombus is a mixture of platelets, erythrocytes and fibrin protein, which begin to accumulate on the wall of the damaged vessel. gradually it thickens and hardens, but in general it resembles a viscous substance, similar to jelly,it can be unambiguously stated that with this virus, from the very beginning, there is an activation of hemostasis, intravascular blood coagulation and thrombus formation in small-caliber vessels of vital organs. In this case, not only the lungs are damaged, but the blockade of microcirculation and its irreversible nature determine the outcome of the disease.