Online ISSN: 2515-8260

Keywords : PSA

Effects Of Obesity On The Serum Levels Of Free And Total Prostate-Specific Antigen In A Sample Of Iraqi Men.

Dr Ziad Hammad Abd; Dr Ruya Abdulhadi M. Saeed; Omar Farhan Ammar (alrawi)

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 8, Pages 142-148

Objectives: the study aims to assess the relationship between obesity and prostatic markers (total prostatic specific antigen (tPSA), and free prostatic specific antigen (fPSA)). Methods: this study was conducted on 127 men aged ≥40 years at The Department of Urology at Al-Ramadi Teaching Hospital. Exclusion criteria were a history of previously diagnosed or treated prostate cancer, the use of prostacare or any drugs that affect the levels of PSA in the serum. Results: the age range of the participants of the study was between 40–80 year. The number of men with normal BMI was 26 (20.47%), 47 men were overweight (37%), 33 men were obese (25.98%), and finally, 21 men were severely obese (16.53%). The mean of parameters total and free prostate-specific antigen (tPSA, fPSA), in the study, were (mean ± SD) (1.683±0.563) ng/ml, (0.537±0.189) ng/ml, respectively. Conclusions: there are no significant relationships between BMI, tPSA, and fPSA, at P≤0.05 in a sample of Iraqi men.

Role of Multiparametric MRI in Evaluation of Prostatic Carcinoma And Its Correlation With Histopathology

Dr.Aishwarya Singh; Dr. Subhashree Das; Dr. Satya Mohapatra; Dr. Niranjan Sahu

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 6, Pages 1190-1199

Prostate cancer remains most mutual malignancy throughout males in India. DRE and PSA are commonly used for clinical and biochemical evaluation of suspected patients. TRUS is the main imaging modality aimed at both benign besides malignant disease. In view of limits of PSA, DRE as well as TRUS, MRI is the evolving modality. PIRADS refers to structured reporting scheme for evaluating prostate cancer. It is based on T2W and Diffusion weighted sequences along with Dynamic contrast enhanced scan which offers additional value for localisation of lesion. This research was carried out at an Eastern India regional health center, where 50 patients were in total. The research involved individuals with DRE offender, unfavorable TRUS controlled biopsy as well as high PSA. Most of the patients with PIRADS 4 and 5 came out to be proastatic adenocarcinoma showing high Gleason score in TRUS guided biopsy.