Online ISSN: 2515-8260

Keywords : bee pollen


The Effect Of Combination Syrup Of Date (Phoenix Dactilyfera) And Bee Pollen On Blood Glucose Levels And Weight Gain Of Normal And Non-Diabetic Pregnant Rats

Asni Annisa Siregar; Sartini .; Veni Hadju

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 8, Pages 173-181

Dates and bee pollen contain of bioactive compounds in the form of flavonoids, polyphenols, magnesium, carbohydrates, proteins, and fats which allow them to affect blood glucose levels and weight gain. This study aims to determine the effect of the combination syrup of date and bee pollen on blood glucose levels and weight gain of pregnant Wistar rats. The combination of date and bee pollen syrup is made of 20.6% w/v of dates and 1.035% w/v of bee pollen in 100 ml of syrup. Then the rats were divided into 4 groups, namely the CMC solution as a control group, date syrup with a dose of 413.2 mg/200 g of rats’ weight, bee pollen syrup at a dose of 20.7 mg/200 g of rats’ weight and combination syrup of dates and bee pollen at a dose of 413.2 mg dates and 20.7 mg bee pollen /200 g BW of rats as the intervention group which were given for 20 days. Furthermore, the examination was carried out 3 times, on day 0, day 13, and day 20. The average of blood glucose levels after the intervention was 87.29 g/dl in the control group, date syrup 78.14 g/dl, bee pollen syrup 84.14 g/dl and the combination syrup 83.29 g/dl, while the average of body weight was 240.57 in the control group, 256.86 date syrup, 244.14 bee pollen syrup, and 265.00 for combination syrup. The results of statistical analysis showed P>0.05, it means that there was no significant difference in the value of glucose levels among each group, but there was a significant difference in the body weight of rats in which P<0.05, so the combination syrup of date and bee pollen is safe to be consumed by pregnant women because it does not affect the blood glucose levels significantly and it can increase their weight.

The Effect Of Giving Dates Syrup Combination (Phoenix Dactylifera) And Bee Pollen On Hemoglobin Levels In Pregnant Wistar Rats (Rattus Novergicus)

Fahriani .; Sartini .; Veni Hadju

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 8, Pages 182-189

Background: Anemia often results from iron deficiency in a pregnant woman as a result of a double iron needs resulting from a rise in blood volume, to meet a mother’s (prevent blood loss at birth) and fetal growth. Dates and bee pollen have the potential to increase hemoglobin because of its complex properties and compositions.
Objective of the study :This study aims to identify the effect of combination of dates and bee pollen syrup towards the hemoglobin level on the pregnant white wistar strain
Reseach method:This research used an experimental research design with randomized post test control group. It used simple random sampling technique by paying attention to inclusion and exclusion criteria, and obtain 28 pregnant white wistar strain rats. The samples were divided into 4 groups. The control group was given cmc solution intervention group was given dates syrup,bee pollen, and the combination of dates syrup and bee pollen,at a dose of 2ml/day for 20 days. Measurement of hemoglobin levels using a hematology analyzer.
Result: The results of this study analyzed using paired T test, Anova test with two factorial design and post Hoc LSD. This study shows that from the statistical test of hemoglobin levels, it obtained an average value in control group before 13.700±0.883 and after treatment 13.314±0.979 with a value (p=0,096,p>0.05), which means there is no difference after treatment while in the intervention group date syrup before treatment 12,500 ± 0.416 and after treatment 13,014 ± 0.644 with value (p = 0.179, p> 0.05) which means there is no difference after treatment. The bee pollen syrup group before treatment was 13.814 ± 0.823 and after treatment 14.014 ± 0.795 with value (p = 0.099, p> 0.05) which means there is no difference after treatment. whereas in the combination of date syrup and bee pollen groups before treatment was 12.971 ± 0.616 and after treatment 15.557± 0.378 with value (p=0.000, p<0.05) which means there is a difference after treatment.
Conclusion: The conclusion of this study is that there is an effect of giving a combination of dates syrup and bee pollen. It is hoped that the next researcher can make a combination of dates syrup and bee pollen which is given to pregnant woman