Online ISSN: 2515-8260

Keywords : ligand

Synthesis And Characterization Of 4- Cyanobenzaldeyde And 4 Methyl Benzaldehyde With Cu(I) Halides

Reena Dhanda; Rekha Sharma

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 3681-3687

Copper (I) halides (X = Cl, Br, I) were reacted with one mole of 4-cyanobenzaldehyde thiosemicarbazone (HL1) and two molar Ph3P to form complexes of general formula, [CuX(HL1)(Ph3P)2] (1-3). However, the similar reaction with 4-methylbenzaldehyde thiosemicarbazone (HL2) did not give the same complex with copper (I) iodide and bromide. Instead of that X = I (A), Br (B) complexes of stiochiometry, [CuX(Ph3P)3] formed. No ligand gets attached to copper centre. Only the copper (I) chloride has formed complex of stiochiometry, [CuCl(HL2)(Ph3P)2] 4. Conformation of formation of complexes was done by infra-red, ultra-violet and nuclear magnetic resonance spectroscopy. All these techniques support binding of thio- ligand to copper center in neutral mode. Binding of trihenylphosphine in these complexes is also confirmed by these techniques.

Synthesis of New Reagents as a ligands and Study of (Investigation, Chromatographic Behavior, Solubility)

Dr. Fatimah A. Wannas; Nemah Sahib Mohammed Husien; Dr. Afaq Jaber Kadhium; Dr. Nagham Mahmood Aljamali

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 5266-5279

Formazane ligands are described by many chemical and physical properties that have increased their applications in several fields and therefore have been classified as reagents or ligands with donor or multi-sites. Multiple methods have been used to prepare aldamine and formazane reagents, including imination reactions, condensation, substitution, duplication, including the formation of the carbanion and the reaction of nitrogen in coupling reaction. It is followed by investigation of prepared ligands by various sources that improved all results in this paper via various spectral measurements in inorganic chemistry area like (Uv-Vis, FT.IR, H.NMR) - spectra, besides to other measurements in analytical area like: (solubility, chromatographic behavior, TLC –plate), besides to bio- assay as antibacterial compounds for determination of efficiency of inhibition and other chemical characterizations (melting points, Rf, …).