Online ISSN: 2515-8260

Keywords : Corticosteroids

A Clinical Study And Management Of Allergic Conjunctivitis In Tertiary Healthcare Centre

Berelli Srilekha; Dr.Sohan Lohiya

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 3464-3472

Background: In the last few decades allergic diseases have increased extensively.Ocular allergy is one of the most common ocular conditionfound in clinical practice.It is considered that allergic diseases are caused due to various factors like pets, dust,pollen grain exposure, air pollution, genetic variation and frequent exposure to allergens in early childhood.Ocular allergy causes signs that are unpleasant and impair their everyday activities
If undertreated, severetype of allergic conjunctivitis, such as atopic keratoconjunctivitis, may potentially lead to visual impairment
.Aim: A clinical study and management of allergic conjunctivitis in tertiary health care centre.
Objectives:To observe an association of dry eye in allergic conjunctivitis.To study the response of different drug therapies in treatment of allergic conjunctivitis.Compare the response of different drug therapies in allergic conjunctivitis.
Material and Method: This is cross sectional observational research will be performed at Acharya Vinoba Bhave rural Hospital (AVBRH) in the Department of Ophthalmology, a tertiary health care teaching hospital located in the Wardha District rural area, among 85 patients regardless of age, gender or ethnicity. Baseline data will be noted.All the patients will be made fully aware of the details of the procedure. The patients fulfilling the inclusion criteria will be sequentially recruited for the study. Clinical history will be taken and Comprehensive ophthalmic examination- slit lamp examination, fundoscopy,tear break up time, schirmer’s test with topical anaesthesia will be performed on patients and patients will be followed at 1, 3 ,6 and 8weeks. All patients will be asked for previous medical history, allergic history and lifestyle factors using a standard questionnaire administered in thestudy. General vital data, higher function status also will benoted. Expected results:The study aims to correlate dry eye in allergic conjunctivitis and to know management of allergic conjunctivitis and efficacy of different standard drugs used for allergic conjunctivitis in patients.

Advanced treatment regimes and application of regenerative medicine for human male infertility treatment

A.S Vickram; G.V. Sree Charan; P. Venkatasaikumar; M. Kusuma; P.N. Ramya Bhargavi; G. Gulothungan; S. Thanigaivel; P. Jeyanthi; R. Nanmaran

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 5746-5766

Male reproductive organ and other assessory sex glands plays an massive role in sperm production process, sperm maturation process, maintaining the entry of sperm cells in the female reproductive tract and until child birth. Many events could happen properly from semen ejaculation until it reaches the oozyte for proper fertilization. Any problem during the process of semen reaching female reproductive tract could men responsible. Overall 20 to 35 % of men contribute to the infertility. Clinical evidence suggests that tissue engineering and regenerative medicine could help men achieve the fertility status. Congenital abnormalities, iatrogenic injuries, trauma and other chronic conditions could be treated by regenerative medicine. Recently stem cell therapy has been emerging in the file of male infertility treatment regimes. In case of trauma, penile reconstruction, testes reconstruction available as most advanced treatment regime. Here we summarized the important findings and functions of testes, penile and scrotum reconstruction techniques, organ based regeneration for various male infertile disorders. Non-obstructive azoospermia conditions will be very tough to diagnose and this review comprises the important treatment regimes available for non-obstructive azoospermia. Antioxidants therapy, trace elements therapy, oral administration of carnitines and its potential applications were carefully elucidated for idiopathic conditions. We also summarized the role of prebiotics and probiotics as treatment regime for male infertility. All advanced treatments methods available were in general summarized in this review.