Online ISSN: 2515-8260

Keywords : Carbon Dioxide


Correlation Of Acid Base And Blood Gas Changes During Laparoscopy And Effects Of Various Insufflating Agents Comparing Carbon Dioxide With Nitrous Oxide At A Tertiary Care Hospital

Kamala Kanta Das, Rahul Laxmishankar Singh .

European Journal of Molecular & Clinical Medicine, 2023, Volume 10, Issue 1, Pages 2774-2780

Background:  Laparoscopy has been used as a therapeutic as well as a diagnostic tool in pelvic and abdominal surgeries. Present study was aimed at to study correlation of acid base and blood gas changes during laparoscopy and effects of various insufflating agents comparing Carbon Dioxide with Nitrous Oxide at a tertiary care hospital. Material and Methods: Present study was hospital based, comparative study, conducted in female patients from age group of 20-40 years in ASA Class – I/II undergoing diagnostic laparoscopy and laparoscopic tubal ligation. Results: We compared effects of pneumoperitoneal insufflating agents among 2 groups of 35 patients each as Group N (Nitrous oxide as the insufflating agent) versus Group C (carbon dioxide as the insufflating agent). The blood gas analysis showed a rise in PaO2 and O2 saturation, due apparent rise mainly to the FiO2. Though the PaO2 is adequate to meet the increase in the tissue oxygen demand, it is inconsistent with the FiO2 (33%) delivered. The post operative and oxygen saturation came back to their pre-operative values. The PaCO2 was significantly higher intra-operatively in both the groups, with numerically high values in Group C. The PeCO2 followed the trend of PaCO2 and the fall of pH was consistent with the rise in PaCO2. Though the rises of the PaCO2 and fall in pH were statistically significant, they did not reach hazardous level. Group N (14.28 %) had more incidences of nausea and vomiting as compared to Group C (5.71 %).
Conclusion: Nitrous oxide appears to be the most suitable insufflating agent, used to produce pneumoperitoneum as compared to carbon dioxide, with general anaesthesia for laparoscopic surgeries.

Study Of The Effects Of Various Insufflating Agents During General Anaesthesia And Correlation Of Acid Base And Gas Blood Changes During Laparoscopy To Determine Ideal Insufflating Agent Amongst CO2, O2 And N2O

Dr Rahul Laxmishankar Singh, Dr. Kamala Kanta Das .

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 1689-1696

Background: Laparoscopy involves the visualization of abdominal and pelvic organs after creating an artificial pneumoperitoneum. Present study was aimed at to study effects of various insufflating agents during general anaesthesia and correlation of acid base and blood gas changes during laparoscopy to determine ideal insufflating agent amongst CO2, O2 and N2O at a tertiary hospital. Material and Methods:  Present study was single-center, comparative study, conducted in female patients from age group of 20-40 years in ASA Class – I/ II undergoing diagnostic laparoscopy and laparoscopic tubal ligation. 105 patients were divided in three groups of 35 patients each as Group- I (oxygen as the insufflating agent), Group II (Nitrous oxide as the insufflating agent) & Group III (carbon dioxide as the insufflating agent).Results: Mean age, body weight & types of procedures were comparable among all groups & no significant statistical difference was noted. The blood gas analysis showed a rise in PaO2 and O2 saturation, due apparent rise mainly to the FiO2. Though the PaO2 is adequate to meet in increased the tissue oxygen demand it is inconsistent with the FiO2 (33%) delivered. The post operative and oxygen saturation came back to their pre-operative values. The PaCO2 was significantly higher intra-operatively in all the three groups, with a numerically high value in Group III. The PECO2 followed the trend of PaCO2 and the fall of pH was consistent with the rise in PaCO2.  Though the rise of the PaCO2& fall in pH was statistically significant, they did not reach hazardous level. The Group I had the highest incidence of nausea and vomiting (88.57 %) followed by Group II (14.28 %). Conclusion:         Nitrous oxide appears to be the most suitable amongst the three gases; Oxygen, Nitrous oxide and carbon dioxide, with general anaesthesia.

Adsorption Energetics In Zsm-5 Zeolites

Kuldasheva Shakhnoza Abdulazizovna; Yakubov Yuldosh Yusupboyevich; Abdulhaev Tolibjon Dolimjonovich; Rakhimova Latofat Sobirjonovna

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 887-901

This article highlights the study on the determination of differential heat, isotherm, thermokinetics and entropy of water, carbon dioxide, normal heptane, benzene, methanol, ethanol adsorption on ZSM-5 zeolites, using adsorption-calorimetric method at a temperature of 303 K. The type and number of formed ion-molecular complexes, as well, the mechanism of adsorption of the studied molecules were ascertained. In the zeolite structure, thermokinetics of adsorption and the discovery of the migration laws of exchange cations are considered the adsorption energy of gases and vapors in a flawless zeolite. From the beginning to the saturation, the adsorption isotherm was described by the two- and three-term mathematical equations of STMP.