European Journal of Molecular & Clinical Medicine

In this paper catalytic vinylation of morpholine with the acetylene at atmospheric pressure with formation of N-vinylmorpholine has been investigated. The influence of nature of catalysts and solvents on vinylation of morpholine in homogeneous conditions is studied. DMSO is chosen as optimal solvent and the effect of temperature influence and amount of catalyst for the vinylation process are investigated. Role of high-basic system KOH/DMSO and its nucleophilic interaction with acetylene has been shown and kinetics of morpholine vinylation is investigated. Heterogeneous catalytic vinylation of morpholine with acetylene in presence of catalysts KOH/AC-L and nanostructural KOH/activated coal has been investigated. Nanostructured KOH/activated coal catalyst proves more effective in the formation of Nvinylmorpholine.

In this work mono- and divinyl esters of adipic acid with using of homogenno-catalytical vinylation by acetylene of adipic acid in solution of dimethylformamide (DMF) in the presence of zinc acetate as catalyst (10% by mass of adipic acid) and AlCl3•6H2O (10% by mass zinc acetate ) in the temperature range of 80-130 °C have been synthesised. The synthesis of divinyl ester of adipic acid has also been studied using vinyl acetate. The influence of the nature of the catalyst and temperature on the yield of the product was studied. The structure of the synthesized mono- and divinyl esters of adipic acid were confirmed by FT-IR, 1H_NMR, LC/MS and 13C-NMR spectral analysis and some their physical constants were determined