Online ISSN: 2515-8260

Keywords : immunology

Determination Of The Immunological Status Of The Oral Cavity Of The Child Population With Congenital Lip And Palate In The Studied Areas

Dildora I. Tailakova; Nazira N. Khabibova

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 3023-3026

In connection with the continuing chemicalization of agriculture in the republic and the increasing intensification of industrial production, the danger of chemical pollution of objects of the human environment, disturbance of the ecological balance and their negative impact on the health of the population increases. As you know, in the conditions of Uzbekistan, the main sources of environmental pollution in rural areas are large-scale use of pesticides and mineral fertilizers, and in industrial cities - emissions from various industrial enterprises; in some cotton-growing regions, there is a combined pollution of the environment with pesticides, mineral fertilizers and industrial emissions

ImmunobiologyOf N-Cov Spike Protein

M. Rithanya; Smiline Girija; M.P. Brundha

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 2965-2972

Immunobiology is the branch of science that deals with immunological effects which includes phenomenan like infectious diseases, growth and development, hypersensitivity, heredity, aging and transplantation. In this review article, we have compiled the immunobiology of the nCoV, which has led to the world wide panic causing a major pandemic. Coronavirus (CoV) is a large family of viruses that has led to mild to severe illness, with magnified cytokine storms in the lungs. The severe forms of these viruses involve Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). A new strain of virus that had not been earlier detected in humans is the Novel coronavirus (nCoV). The major structural protein, the spike protein S seems to be the highly potent moiety involved with viral fusion and entry into the host cells through ACE receptors. This review thus throws insights into the immuno-biology of the spike protein and its role in the immuno-pathogenesis of CoV.