Online ISSN: 2515-8260

Keywords : novel coronavirus

Assessment of dental practitioner’s perception of COVID-19 pandemic effects on their clinical practice: A questionnaire-based study

Sridevi Ugrappa; Ajay Jain; Vijay Kumar Ugrappa

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 2931-2943

Aim: To evaluate the dentist’s perception regarding the effects of COVID-19 pandemic on
their clinical practice in the post-lockdown period.
Materials and Methods: The present study was conducted among dentists, practicing in
India, through an online close-ended structured questionnaire. Both convenience and
snowball sampling were used for the distribution of online forms. The frequency
distribution test and chi-square test (α=0.05) were performed for the demographics, clinical
expenditure of the dentists & treatment provided to the patients by the dentists and to
evaluate their perception of clinical practice in post-lockdown period, respectively. The null
hypothesis stated that there is no difference in their clinical practices and alternative
hypothesis stated that the dentists did anticipate and felt the change in their clinical
practices amid COVID-19 pandemic. The data were tabulated and analysed using IBM
SPSS for Windows, v. 21.0 (IBM Corp., Armonk, USA).
Results: The response rate was 98.52% and the p-valuefor all the questions related to the
perception of their clinical practice amid COVID-19 pandemic was less than 0.05,
suggested that the dentists have anticipated and felt that there will be a change in their
clinical practice amid COVID-19 pandemic.

ImmunobiologyOf N-Cov Spike Protein

M. Rithanya; Smiline Girija; M.P. Brundha

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 2965-2972

Immunobiology is the branch of science that deals with immunological effects which includes phenomenan like infectious diseases, growth and development, hypersensitivity, heredity, aging and transplantation. In this review article, we have compiled the immunobiology of the nCoV, which has led to the world wide panic causing a major pandemic. Coronavirus (CoV) is a large family of viruses that has led to mild to severe illness, with magnified cytokine storms in the lungs. The severe forms of these viruses involve Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). A new strain of virus that had not been earlier detected in humans is the Novel coronavirus (nCoV). The major structural protein, the spike protein S seems to be the highly potent moiety involved with viral fusion and entry into the host cells through ACE receptors. This review thus throws insights into the immuno-biology of the spike protein and its role in the immuno-pathogenesis of CoV.