Online ISSN: 2515-8260

Keywords : Pleomorphic Adenoma


Dr. Shiping Jain, Dr.Sandeep Kumar Jain, Dr. Balwant Singh Patle, Dr. Krithika T

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 11138-11148

Introduction: Major salivary glands pathologies are a significant source of morbidity in
general population. The role of ultrasonography in evaluation of salivary glands masses
is become increasingly important due to availability of high frequency probe which
permit visualization of more subtle anatomical and pathological details.
Objectives: The study was conducted to determine the diagnostic role of real-time
ultrasonography& color Doppler in diagnosis of major salivary gland tumors.
Material and methods: This study was conducted in the Radiodiagnosis,
DepartmentofGajra Raja Medical College andHospitals, Gwalior (M.P.) in USG
Machine SSD4000SV (AlokaTrivitron) from August 2011 to September2012. A total 46
patients was enrolled in study after taking detailed history and relevant clinical
examination. Subsequently the patient was subjected to real time
ultrasonographyfollowed by histological examination by On-site fine needle aspiration
Results: According to the study out of 46 major salivary gland tumors, benign tumors
32(69.57%)were morecommon than malignant 14 (30.43%).The age distribution of the
patients with salivary gland neoplasm ranged from 1-80 years and majority of belongs
to the 30-70 years age group.Male : Female ratio for malignant tumors is 6:1 and equal
in benign tumors.
European Journal of Molecular & Clinical Medicine
ISSN 2515-8260 Volume 9, Issue 3, Winter 2022
Parotid gland was the most common site accounting for 91.30% followed by
submandibular gland (8.7%) of all salivary gland tumors. On USG examination all
tumors were hypoechogenic. Most benign tumors (87.5%) had well defined borders, but
12.5% of malignant tumors also had well defined (sharp) borders. The internal
structure of tumor was not a relevant indicator of malignancy. According to the study
the commonest tumors was pleomorphic adenoma which accounted for 60.87% of all
cases followed by mucoepidermoid carcinoma( 17.4%)of all cases confirmed by
histopathological examination.
Conclusion: Ultrasonography is a highly sensitive, specific,easily available and
affordable imaging modality to assess salivary gland tumors.however it is more sensitive
for detecting benign tumors and more specific for malignant tumors.

Clinical profile of patients with benign parotid disease at a tertiary care hospital

Dr. Arunkumar Tukaram,Dr. Md. Zaheeruddine Ather,Dr. Arunkumar Bhavikatti,Dr sharankumar Jabshetty

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 1, Pages 184-189

The analogue of the parotid gland is the first gland to form in humans. Lesions of the parotid
gland are fairly easy to recognize mainly because of the location and limited number of
structures present here. Tumors of parotid gland are believed to represent approximately 2%
of head and neck tumors. Parotid gland tumors account for 70- 80% of all tumors of salivary
glands. Patients visiting to surgery department with parotid swelling were subjected to careful
history taking, complete clinical examination, and examination of facial nerve integrity.
Clinical diagnosis made was confirmed with USG (ultra sonography) parotid and FNAC (fine
needle aspiration cytology). 14(70%) patients in antegrade group vs. 13(76.47%) patients in
retrograde group had pleomorphic adenoma, 5 (25%) patients in antegrade group vs.2
(11.76%) patients in retrograde group had Warthin’sTumor,1(5%) patients in antegrade group
vs.2 (11.76%) patients in retrograde group had Recurrent Pleomorphic Adenoma.


Hanan Abdulqader Abdullah, Dijwar Salih Ibrahim, Ibrahim Naqid

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 9, Pages 3912-3916

(Background: The salivary glands have an important role in the functions of digestion
by making lubrication fluid, respiration, speech, and overall homeostasis, and they also
contain antibodies. Generally, the salivary gland tumors might be categorized into non
inflammatory, inflammatory, and neoplastic swellings such as calculi, benign tumors
like Warthin tumor, oncocytoma, pleomorphic adenoma, malignant tumors involving
undifferentiated carcinoma, adenoid cystic carcinoma, and adenocarcinoma.
Methodology: This epidemiological study is carried out at the Department of
histopathology, Zakho general hospital, thirty salivary glands cases are involved in this
work in a period of 15-years.
Results: There are 30 patients with major salivary gland tumors, while 26 patients
(86.666) had parotid and 4 patients (13.333) had sub-mandibular major salivary gland
tumors. In the presented work, 26 (86.666) cases from a total of 30 salivary tumor cases
have been benign, while only 4 (13.333) are malignant, from a total of 26 patents of
parotid tumors, overall of 20(76.923) cases have been identified in superficial lobe,
whereas only 6(23.076) cases have been in deep lobe, from a total of 30 salivary gland
tumors, overall of 26(86.666) cases are pleomorphic adenoma and just 3 (11.538%)
cases are mucoepidermoid carcinoma and only single case (3.333%) has been acinic cell
Conclusions: The parotid gland has been defined as the major site of origin which is
related to benign as well as malignant tumors, also the pleomorphic adenoma is the
major benign salivary gland tumor and mucoepidermoid carcinoma is the major
common malignant tumor. The rest of the cases are autoimmune disease and minor
salivary gland tumors.