Online ISSN: 2515-8260

Keywords : antiepileptic drugs

A study of 50 cases of seizures in adults and it’s clinical profile

Dr Bhavikkumar Prajapati, Dr Janak Chokshi, Dr Krunal Talsaniya .

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 3039-3047

: Introduction: Seizure disorder is a one of major health problem in adults mostly in late adulthood in which chances of seizures are increased especially due to comorbidities like cerebrovascular stroke, CNS infection, degenerative disease of brain, and brain tumor. So we study 50 adult patients to identify various etiology of seizures.
Materials and methods: We check for various parameters like complete blood count, blood sugar level, renal function tests with electrolytes, liver function tests, brain imaging and Electroencephalogram. Result: With the help of this study, we identify that most common cause for seizure is idiopathic in less than 50 years of age and post stroke epilepsy in more than 50 years of age. Generalised tonic clonic seizure is most common type of seizure. With the help of newer neuro-imaging modalities and EEG it is possible to find out specific etiology of seizure, so EEG and imaging study should be integral part of investigation work of patient with seizure disorder.
Conclusion: The present study was an effort to find out the various etiology, type of seizures in adults, clinical profile and response to antiepileptic drugs. Every patient should be investigated thoroughly and diagnosed and best suitable drug given depending upon type of seizures to the patient for proper control of seizures and also improve morbidity and mortality due to seizures.

The Modern Approach To The Management Of Pregnancy And Childbirth In Women With Epilepsy

Fotima Khodjaeva Taxirovna

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 3357-3363

The onset of pregnancy in a woman with epilepsy is not only desirable but also a very important stage in life. Therefore, a patient of fertile age needs to explain immediately at her first visit to an epileptologist that this event, like any good impromptu, should be planned. The ability to have children with epilepsy in women is reduced by an average of 2 times compared with the general population. This is due to both social and organic reasons. Pregnancy is contraindicated only for women with severe epilepsy, when the use of AED does not allow avoiding frequent generalized seizures, in addition, the woman has severe mental disorders. Epilepsy is not a contraindication to IVF, although one should not forget that to stimulate the production of an egg, women who are candidates for IVF are massively injected with hormonal drugs. This can sometimes trigger seizures.